iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052705

Ensembl Protein ID

ENSLOCP00000012373.1

UniProt Accession

W5MVG4; W5MVG4_LEPOC

Genbank Protein ID

ENSLOCP00000012373

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01034623

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000010114.1	ENSLOCT00000012394.1	ENSLOCP00000012373.1
ENSLOCG00000010114.1	ENSLOCT00000012403.1	ENSLOCP00000012382.1
ENSLOCG00000010114.1	ENSLOCT00000012411.1	ENSLOCP00000012390.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.90e-75	253.7	43	480

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re l++  +e+l   ++k++ +     +  +lq+lf+ l+  +++a s+ +l+++++++++e  +
   Q: 43   GIRNQGGTCYLNSLLQTLLFTPEFREVLFSLGPEELGYLSDKDKPEakvrVIPLELQRLFAYLLLVDQQAASTADLTDSFGWTSNE--E 129
           9*****************************88888877655443334555899*******************************98..9 PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++qqD+qE+ ++l+++le++l                            ++++++is+l++g++ +qi+c+ec+nvs+r+e+ ldl+++
   Q: 130  TSQQDVQELNRILFSALESSL--------------------------VGTSGSDIISRLYHGTVVNQIVCKECGNVSERQEDILDLTVS 192
           *********************..........................7899************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v+g +      l ++L ++f++ee +eg+n y c+ c ++++a k+ kl+klP++L++ L Rfsf+ +++ r k + +++fp +++l+p
   Q: 193  VKGLS-----GLLEALwSMFVEEEFFEGNNLYRCSCCGNLVTAAKSAKLRKLPPFLTISLLRFSFDFTKCERYKETGRYTFPVRMNLRP 276
           *****.....677777699********************************************************************** PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc++ e++++ +++YeL++v++H+G++ +GHY++y+k+                                                   
   Q: 277  FCEQAERADS-EYEYELFSVIIHKGGCYGGHYHVYIKDldqlgnwespeeeakpklpkkdvkapdselevedplavlkailsqeeskti 364
           ****888875.9***************************************************************************** PP
   S: 302  ..............................................................................ekgkWllfdDs 312
                                                                                         ++++W+ ++D+
   Q: 365  lvdqlgqklldkigvswnkkfrkqhgpigkflqshadvfllvsngtqvqlkpngleavepsqkadpvtpertevpvpgDEHHWFDLNDT 453
           ************************************************************9999999999999999888888******* PP
   S: 313  kVtevkeeevleetg..staYvlfYkr 337
           +V++++e++++++ +  ++aY+lfY++
   Q: 454  SVQPIREQDIEKQFQgkESAYMLFYRK 480
           ************9889*********97 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MFGNLFEEDD AAFVPQSTSS DGRKCQGKNS EPPPPRGMVN LSGIRNQGGT CYLNSLLQTL 60
LFTPEFREVL FSLGPEELGY LSDKDKPEAK VRVIPLELQR LFAYLLLVDQ QAASTADLTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGCCGTCC GCTTCTGCTT AAAAAACATG GCCGCACACA CGATGGGTAT TTTTATTTAC 60
GTTCTGTGCT TCGTTTCAGT GGAAATGAAA GTAGTTGAGA TTTGTTTCGT CTAGGAACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	54.97	0.00e+00	1182.00
IUUC-Apl-004105	Anas platyrhynchos	55.78	0.00e+00	1332.00
IUUC-Aca-004715	Anolis carolinensis	54.45	0.00e+00	1261.00
IUUC-Ame-011073	Astyanax mexicanus	56.91	0.00e+00	1314.00
IUUC-Bta-012487	Bos taurus	54.28	0.00e+00	1236.00
IUUC-Cja-018937	Callithrix jacchus	54.55	0.00e+00	1261.00
IUUC-Cfa-020645	Canis familiaris	46.09	0.00e+00	629.00
IUUC-Cpo-022160	Cavia porcellus	53.66	0.00e+00	1241.00
IUUC-Csa-023078	Chlorocebus sabaeus	54.07	0.00e+00	1273.00
IUUC-Cho-025013	Choloepus hoffmanni	38.46	4.00e-116	412.00
IUUC-Csv-026193	Ciona savignyi	54.51	4.00e-56	211.00
IUUC-Dre-027416	Danio rerio	61.66	0.00e+00	1485.00
IUUC-Dno-029639	Dasypus novemcinctus	50.19	0.00e+00	966.00
IUUC-Dor-030624	Dipodomys ordii	71.71	6.00e-120	425.00
IUUC-Ete-032626	Echinops telfairi	42.17	7.00e-122	431.00
IUUC-Eca-034208	Equus caballus	54.17	0.00e+00	1259.00
IUUC-Fca-036006	Felis catus	70.03	5.00e-154	536.00
IUUC-Fal-036925	Ficedula albicollis	55.81	0.00e+00	1244.00
IUUC-Gmo-038597	Gadus morhua	56.18	0.00e+00	1163.00
IUUC-Gga-041171	Gallus gallus	54.88	0.00e+00	1285.00
IUUC-Gac-041362	Gasterosteus aculeatus	58.88	0.00e+00	1269.00
IUUC-Ggo-045069	Gorilla gorilla	53.04	0.00e+00	1114.00
IUUC-Hsa-046715	Homo sapiens	54.47	0.00e+00	1248.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	52.55	0.00e+00	1185.00
IUUC-Lch-050182	Latimeria chalumnae	53.68	0.00e+00	1205.00
IUUC-Laf-054132	Loxodonta africana	54.70	0.00e+00	1280.00
IUUC-Mcc-055734	Macaca mulatta	54.57	0.00e+00	1269.00
IUUC-Meu-056135	Macropus eugenii	78.79	8.00e-104	372.00
IUUC-Mga-060092	Meleagris gallopavo	54.99	0.00e+00	1278.00
IUUC-Mmr-061546	Microcebus murinus	53.02	0.00e+00	1157.00
IUUC-Mdo-061935	Monodelphis domestica	52.16	0.00e+00	1231.00
IUUC-Mmu-063630	Mus musculus	53.64	0.00e+00	1249.00
IUUC-Mpu-066579	Mustela putorius furo	53.85	0.00e+00	1263.00
IUUC-Mlu-068034	Myotis lucifugus	53.88	0.00e+00	1199.00
IUUC-Nle-069082	Nomascus leucogenys	50.05	0.00e+00	967.00
IUUC-Opr-070953	Ochotona princeps	44.18	7.00e-152	531.00
IUUC-Ont-072435	Oreochromis niloticus	60.20	0.00e+00	1460.00
IUUC-Oan-073339	Ornithorhynchus anatinus	54.74	0.00e+00	1249.00
IUUC-Ocu-073760	Oryctolagus cuniculus	54.86	0.00e+00	1253.00
IUUC-Ola-087015	Oryzias latipes	58.87	0.00e+00	1216.00
IUUC-Oga-088960	Otolemur garnettii	53.99	0.00e+00	1243.00
IUUC-Oar-089853	Ovis aries	53.71	0.00e+00	1242.00
IUUC-Ptr-091093	Pan troglodytes	54.47	0.00e+00	1244.00
IUUC-Pan-091962	Papio anubis	53.59	0.00e+00	1259.00
IUUC-Psi-093691	Pelodiscus sinensis	56.43	0.00e+00	1338.00
IUUC-Pma-094428	Petromyzon marinus	65.12	2.00e-91	328.00
IUUC-Pfo-096983	Poecilia formosa	58.95	0.00e+00	1312.00
IUUC-Pab-097860	Pongo abelii	53.55	0.00e+00	1145.00
IUUC-Pca-100514	Procavia capensis	56.35	5.00e-126	445.00
IUUC-Pva-102771	Pteropus vampyrus	53.02	0.00e+00	1147.00
IUUC-Rno-105405	Rattus norvegicus	53.06	0.00e+00	1239.00
IUUC-Sha-107376	Sarcophilus harrisii	53.16	0.00e+00	1184.00
IUUC-Ssc-115819	Sus scrofa	47.74	0.00e+00	760.00
IUUC-Tgu-117262	Taeniopygia guttata	55.44	0.00e+00	1322.00
IUUC-Tru-117601	Takifugu rubripes	60.33	0.00e+00	1446.00
IUUC-Tsy-118996	Tarsius syrichta	45.72	0.00e+00	899.00
IUUC-Tni-120682	Tetraodon nigroviridis	51.38	0.00e+00	1106.00
IUUC-Tbe-127616	Tupaia belangeri	42.60	0.00e+00	630.00
IUUC-Ttr-129075	Tursiops truncatus	51.73	0.00e+00	1128.00
IUUC-Vpa-130108	Vicugna pacos	54.57	0.00e+00	1109.00
IUUC-Xtr-132623	Xenopus tropicalis	50.48	0.00e+00	1179.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence