iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA
DNA & RNA Element
miRTarBase	TRANSFAC	miRcode	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	HINT
Mentha	InWeb_IM
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-19	70.2	192	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDl 30
           gH+d+++++a+ sdt  vsGs+Dgt+ +W++
   Q: 192  GHKDWIFAVAWlSDTVAVSGSRDGTVALWRM 222
           8***********99***************96 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MAQQQTGSRK RKAPAVEAGA GSSSSQGLAA ADGEGPLLPK KQKRPATRRR LVHYLKGREV 60
GARGPAGLQG FEGELRGYAV QRLPELLTER QLDLGTLNKV FASQWLNARQ VVCGTKCNTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCGCACCAGC TTCTTGGTCT TAGAGATCCT GAGCTCTCGG CTGACGCGGA AGCGCAGCCA 60
TCCCCACCAC CGCCGCCACG GCCAACACGG GTGCCACGCG CCGCCACCGC CGCCGGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

KEGG

hsa:340578

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001665	Ailuropoda melanoleuca	90.14	0.00e+00	712.00
IUUC-Cja-019567	Callithrix jacchus	94.38	0.00e+00	843.00
IUUC-Cfa-021077	Canis familiaris	88.12	0.00e+00	719.00
IUUC-Cpo-022378	Cavia porcellus	81.75	0.00e+00	675.00
IUUC-Dno-029097	Dasypus novemcinctus	83.01	0.00e+00	744.00
IUUC-Dor-030162	Dipodomys ordii	79.58	0.00e+00	665.00
IUUC-Fca-035737	Felis catus	88.44	0.00e+00	676.00
IUUC-Ggo-044768	Gorilla gorilla	99.57	0.00e+00	880.00
IUUC-Itr-049055	Ictidomys tridecemlineatus	85.56	0.00e+00	734.00
IUUC-Laf-054329	Loxodonta africana	83.80	0.00e+00	733.00
IUUC-Mcc-055186	Macaca mulatta	98.92	0.00e+00	875.00
IUUC-Mmr-060825	Microcebus murinus	85.75	0.00e+00	754.00
IUUC-Mmu-063116	Mus musculus	81.24	0.00e+00	733.00
IUUC-Mpu-066373	Mustela putorius furo	90.41	0.00e+00	720.00
IUUC-Mlu-067830	Myotis lucifugus	85.03	0.00e+00	751.00
IUUC-Ocu-074250	Oryctolagus cuniculus	80.70	0.00e+00	734.00
IUUC-Oga-088793	Otolemur garnettii	90.73	0.00e+00	756.00
IUUC-Oar-089810	Ovis aries	87.04	0.00e+00	788.00
IUUC-Ptr-091017	Pan troglodytes	99.57	0.00e+00	880.00
IUUC-Pca-100731	Procavia capensis	75.80	0.00e+00	690.00
IUUC-Pva-102699	Pteropus vampyrus	89.53	0.00e+00	783.00
IUUC-Rno-105773	Rattus norvegicus	79.36	0.00e+00	694.00
IUUC-Ssc-115607	Sus scrofa	86.42	0.00e+00	760.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence