iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053587

UUCD1 version

UUC-LoA-00331

Ensembl Protein ID

ENSLAFP00000008237.3

UniProt Accession

G3T4F7; G3T4F7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009831.3	ENSLAFT00000009827.3	ENSLAFP00000008237.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-38	128.9	11	43
E3 activity/RING/U-box	1.40e-23	83.1	404	475
UBD/Beta-Prp	7.10e-53	180.1	7	219

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrtgv 34
           H d+v+c+afs+ ll+++s D+ti++++l+++ 
   Q: 11   HGDDVNCCAFSSSLLATCSLDKTIRLYSLSDFS 43
           9*********548***************98875 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+ef+CpI+ elM++Pv++++G++y+++++e w+ ++++t+P+t+  l +  l+Pn tl+  i++w+e+++
   Q: 404  IPDEFICPITRELMKEPVIASDGYSYEKEAMENWIGKKKRTSPMTNLILPSVVLTPNRTLKMAIDRWLETHQ 475
           8********************************************************************997 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtl 90
           tl +h ++v +c +f  ++sllat s d+ti+++++++ +    + l+ h+ +v  ++fsp+g +l+++s+D+t  +w++++g+++ ++
   Q: 7    TLADHGDDV-NCCAF--SSSLLATCSLDKTIRLYSLSDFSElpHSPLKFHTYAVHWCCFSPSGHLLASCSTDGTTVLWNMQNGQTLAVM 92
           555666655.55888..999999999999999999999776666778999999999999999999999999999999999999999999 PP
   S: 91   kghe.dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgg 178
           ++ + + v+ ++fsp++  lvsG +d t+ +w++++++  + + s++dg+    +++p+g+l+v+Gs  + + +Wd   +++l+  +  
   Q: 93   EQPSgSPVRVCRFSPDSTCLVSGAADGTVVLWNTQSYKLHR-CGSVKDGSLVACAFSPSGDLFVTGSSCGDLTVWDD-KMRCLHSEKA- 178
           96552679999999999999999999999999999988888.99999999999999999999999999999999998.5678888776. PP
   S: 179  htdsvyslsfdsng..........kelvsgsldgtvklwdl 209
           h+  +++ +f+s+           ++l+s+++d ++k+w +
   Q: 179  HDLGITCCDFSSQPvsdgaqdlqfFRLASCGQDCQIKIWIV 219
           99999999999988999999999999999999999999966 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MVKLIHTLAD HGDDVNCCAF SSSLLATCSL DKTIRLYSLS DFSELPHSPL KFHTYAVHWC 60
CFSPSGHLLA SCSTDGTTVL WNMQNGQTLA VMEQPSGSPV RVCRFSPDST CLVSGAADGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGAAAC TAATTCACAC ATTAGCCGAT CATGGTGACG ATGTCAATTG TTGTGCCTTC 60
TCCTCCTCCC TCTTGGCTAC TTGCTCCTTG GACAAAACAA TCCGCCTGTA CTCTTTAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

lav:100653906

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000612	Aegilops tauschii	52.24	5.00e-17	83.20
IUUC-Aml-001614	Ailuropoda melanoleuca	92.02	0.00e+00	919.00
IUUC-Apl-003529	Anas platyrhynchos	75.00	0.00e+00	754.00
IUUC-Aca-004257	Anolis carolinensis	70.64	0.00e+00	700.00
IUUC-Ame-011357	Astyanax mexicanus	52.19	2.00e-116	412.00
IUUC-Bta-013032	Bos taurus	88.05	0.00e+00	878.00
IUUC-Cja-018743	Callithrix jacchus	91.18	0.00e+00	910.00
IUUC-Cfa-021197	Canis familiaris	90.34	0.00e+00	907.00
IUUC-Cpo-022279	Cavia porcellus	89.08	0.00e+00	895.00
IUUC-Csa-023954	Chlorocebus sabaeus	92.44	0.00e+00	916.00
IUUC-Cho-025083	Choloepus hoffmanni	74.60	5.00e-160	556.00
IUUC-Cin-025786	Ciona intestinalis	34.21	1.00e-78	287.00
IUUC-Dre-028087	Danio rerio	56.79	5.00e-143	501.00
IUUC-Dno-028919	Dasypus novemcinctus	92.65	0.00e+00	924.00
IUUC-Dor-031112	Dipodomys ordii	88.03	0.00e+00	877.00
IUUC-Ete-032405	Echinops telfairi	90.67	0.00e+00	650.00
IUUC-Eca-033254	Equus caballus	89.92	0.00e+00	896.00
IUUC-Eeu-034545	Erinaceus europaeus	84.87	0.00e+00	822.00
IUUC-Fca-035482	Felis catus	91.60	0.00e+00	914.00
IUUC-Fal-036976	Ficedula albicollis	60.08	7.00e-160	556.00
IUUC-Gmo-039213	Gadus morhua	55.67	4.00e-138	484.00
IUUC-Gga-040561	Gallus gallus	73.17	0.00e+00	735.00
IUUC-Gac-041471	Gasterosteus aculeatus	58.61	3.00e-143	501.00
IUUC-Ggo-045503	Gorilla gorilla	92.44	0.00e+00	919.00
IUUC-Hsa-045910	Homo sapiens	92.65	0.00e+00	920.00
IUUC-Hvu-047519	Hordeum vulgare	51.52	2.00e-16	80.90
IUUC-Itr-048214	Ictidomys tridecemlineatus	89.12	0.00e+00	703.00
IUUC-Loc-052307	Lepisosteus oculatus	59.52	1.00e-167	582.00
IUUC-Mcc-055679	Macaca mulatta	92.44	0.00e+00	920.00
IUUC-Meu-055962	Macropus eugenii	71.64	0.00e+00	660.00
IUUC-Mga-059652	Meleagris gallopavo	72.96	0.00e+00	740.00
IUUC-Mmr-060943	Microcebus murinus	89.33	0.00e+00	890.00
IUUC-Mdo-062592	Monodelphis domestica	82.67	0.00e+00	822.00
IUUC-Mmu-063577	Mus musculus	80.88	0.00e+00	803.00
IUUC-Mpu-066422	Mustela putorius furo	90.55	0.00e+00	904.00
IUUC-Mlu-067250	Myotis lucifugus	90.13	0.00e+00	894.00
IUUC-Nle-069517	Nomascus leucogenys	92.23	0.00e+00	918.00
IUUC-Opr-070776	Ochotona princeps	89.71	0.00e+00	881.00
IUUC-Ont-071821	Oreochromis niloticus	57.95	1.00e-151	529.00
IUUC-Oan-073706	Ornithorhynchus anatinus	82.95	0.00e+00	831.00
IUUC-Ocu-074766	Oryctolagus cuniculus	82.71	0.00e+00	802.00
IUUC-Ola-086531	Oryzias latipes	58.11	4.00e-149	521.00
IUUC-Oga-088388	Otolemur garnettii	88.45	0.00e+00	891.00
IUUC-Oar-089748	Ovis aries	88.26	0.00e+00	876.00
IUUC-Ptr-090616	Pan troglodytes	92.18	0.00e+00	911.00
IUUC-Pan-091769	Papio anubis	92.73	0.00e+00	664.00
IUUC-Psi-093334	Pelodiscus sinensis	78.57	0.00e+00	729.00
IUUC-Pma-094383	Petromyzon marinus	48.14	2.00e-131	462.00
IUUC-Pfo-096801	Poecilia formosa	56.16	5.00e-146	510.00
IUUC-Pab-098139	Pongo abelii	92.27	0.00e+00	747.00
IUUC-Pca-100523	Procavia capensis	78.99	0.00e+00	756.00
IUUC-Pva-102286	Pteropus vampyrus	88.87	0.00e+00	859.00
IUUC-Rno-104831	Rattus norvegicus	82.56	0.00e+00	820.00
IUUC-Sha-107499	Sarcophilus harrisii	82.98	0.00e+00	832.00
IUUC-Sar-113389	Sorex araneus	85.08	0.00e+00	827.00
IUUC-Tgu-116769	Taeniopygia guttata	71.01	0.00e+00	709.00
IUUC-Tru-118774	Takifugu rubripes	54.71	5.00e-140	491.00
IUUC-Tsy-119595	Tarsius syrichta	79.61	0.00e+00	643.00
IUUC-Tni-119850	Tetraodon nigroviridis	57.42	3.00e-147	514.00
IUUC-Tur-126683	Triticum urartu	51.52	7.00e-17	82.80
IUUC-Tbe-127938	Tupaia belangeri	81.64	5.00e-146	509.00
IUUC-Ttr-128193	Tursiops truncatus	89.62	0.00e+00	754.00
IUUC-Vpa-130275	Vicugna pacos	90.76	0.00e+00	900.00
IUUC-Xtr-131982	Xenopus tropicalis	61.26	2.00e-171	595.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence