iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050489

Ensembl Protein ID

ENSLACP00000002182.1

UniProt Accession

H2ZXR1; H2ZXR1_LATCH

Genbank Protein ID

ENSLACP00000002182

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01044389

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000001950.1	ENSLACT00000002199.1	ENSLACP00000002182.1
ENSLACG00000001950.1	ENSLACT00000002198.1	ENSLACP00000002181.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.20e-32	108.3	5	41
UBD/Beta-Prp	1.30e-48	165.9	2	151

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf......sdtllvsGsdDgtikvWDlrt 32
           gHt++v+++ f      + +l +++sdDgt+kvWD+ t
   Q: 5    GHTERVSGFTFsphlgqP-DLCATCSDDGTVKVWDVQT 41
           8***********998644.899*************976 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkgh.edsvlslsfsp.sgdklvsGshdrtirvwdletgqcle 130
           +l gh++ v+  +fsp+     + +t+s+D+t+kvwd++t   +   + h +++ ++l++sp  +d +vsG++  ++ ++ ++++ + +
   Q: 2    ELIGHTERVSGFTFSPHLGqpdLCATCSDDGTVKVWDVQTKAVINEHRVHqTNTMTALHWSPlVKDLVVSGDEKGIVICY-WSNRNETQ 89
           5789************987788**********************9999651677889*****888**************9.88888888 PP
   S: 131  etlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfdsng 192
             + ++ + v c++ +p   ++++ G +D+++ + d+ + g+++++l+g h+d ++s++++++ 
   Q: 90   -HFFPEPRNVFCLSCSPHHeDYIAVGYKDGMIVIIDIsRKGEVIHRLRG-HDDEIHSIAWSPQP 151
           .8888888999999999999*****************999********9.*********99975 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

GELIGHTERV SGFTFSPHLG QPDLCATCSD DGTVKVWDVQ TKAVINEHRV HQTNTMTALH 60
WSPLVKDLVV SGDEKGIVIC YWSNRNETQH FFPEPRNVFC LSCSPHHEDY IAVGYKDGMI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGAGCTGA TAGGACACAC TGAGCGTGTT TCTGGATTTA CCTTTTCTCC CCACCTTGGT 60
CAGCCAGACC TCTGTGCTAC CTGCTCCGAT GATGGAACTG TGAAGGTTTG GGATGTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016021--C:integral component of membrane

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	51.53	0.00e+00	910.00
IUUC-Apl-003586	Anas platyrhynchos	57.34	0.00e+00	680.00
IUUC-Aca-004956	Anolis carolinensis	55.90	0.00e+00	673.00
IUUC-Ame-010753	Astyanax mexicanus	46.45	4.00e-169	589.00
IUUC-Bta-012315	Bos taurus	57.32	0.00e+00	665.00
IUUC-Cja-019334	Callithrix jacchus	56.77	0.00e+00	669.00
IUUC-Cfa-021254	Canis familiaris	51.43	0.00e+00	922.00
IUUC-Cpo-021984	Cavia porcellus	53.85	0.00e+00	648.00
IUUC-Csa-023650	Chlorocebus sabaeus	56.46	0.00e+00	675.00
IUUC-Cho-024860	Choloepus hoffmanni	49.71	0.00e+00	876.00
IUUC-Cin-025778	Ciona intestinalis	36.73	3.00e-110	393.00
IUUC-Csv-026313	Ciona savignyi	35.10	3.00e-104	372.00
IUUC-Dre-028096	Danio rerio	46.57	4.00e-171	595.00
IUUC-Dno-029799	Dasypus novemcinctus	50.57	0.00e+00	904.00
IUUC-Dor-030885	Dipodomys ordii	55.24	2.00e-73	271.00
IUUC-Dme-031744	Drosophila melanogaster	29.17	9.00e-11	63.20
IUUC-Ete-032918	Echinops telfairi	48.76	0.00e+00	839.00
IUUC-Eca-034144	Equus caballus	50.95	0.00e+00	895.00
IUUC-Eeu-034843	Erinaceus europaeus	57.39	0.00e+00	650.00
IUUC-Fca-035948	Felis catus	57.43	0.00e+00	679.00
IUUC-Fal-037303	Ficedula albicollis	49.95	0.00e+00	902.00
IUUC-Gmo-039591	Gadus morhua	46.07	2.00e-86	313.00
IUUC-Gga-040570	Gallus gallus	58.40	0.00e+00	698.00
IUUC-Gac-042646	Gasterosteus aculeatus	43.70	0.00e+00	789.00
IUUC-Ggo-045605	Gorilla gorilla	43.73	0.00e+00	671.00
IUUC-Hsa-046122	Homo sapiens	57.21	0.00e+00	671.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	56.37	0.00e+00	656.00
IUUC-Loc-052259	Lepisosteus oculatus	46.50	1.00e-169	590.00
IUUC-Laf-053338	Loxodonta africana	51.62	0.00e+00	912.00
IUUC-Mcc-055442	Macaca mulatta	56.77	0.00e+00	677.00
IUUC-Meu-056245	Macropus eugenii	46.05	2.00e-97	351.00
IUUC-Mga-060202	Meleagris gallopavo	44.88	0.00e+00	782.00
IUUC-Mmr-061730	Microcebus murinus	46.83	0.00e+00	844.00
IUUC-Mdo-062880	Monodelphis domestica	51.38	0.00e+00	930.00
IUUC-Mmu-063930	Mus musculus	49.79	0.00e+00	640.00
IUUC-Mpu-066605	Mustela putorius furo	51.34	0.00e+00	914.00
IUUC-Mlu-067765	Myotis lucifugus	57.98	0.00e+00	685.00
IUUC-Nle-069183	Nomascus leucogenys	56.46	0.00e+00	671.00
IUUC-Opr-070659	Ochotona princeps	54.76	1.00e-102	368.00
IUUC-Ont-072356	Oreochromis niloticus	40.38	0.00e+00	741.00
IUUC-Oan-073056	Ornithorhynchus anatinus	56.90	0.00e+00	657.00
IUUC-Ocu-073881	Oryctolagus cuniculus	49.86	0.00e+00	899.00
IUUC-Ola-087120	Oryzias latipes	55.97	4.00e-55	207.00
IUUC-Oga-088343	Otolemur garnettii	50.57	0.00e+00	914.00
IUUC-Oar-089257	Ovis aries	47.38	0.00e+00	876.00
IUUC-Ptr-090497	Pan troglodytes	57.36	0.00e+00	669.00
IUUC-Pan-092638	Papio anubis	56.39	0.00e+00	660.00
IUUC-Psi-093096	Pelodiscus sinensis	60.03	0.00e+00	707.00
IUUC-Pma-094571	Petromyzon marinus	37.58	6.00e-61	228.00
IUUC-Pfo-096742	Poecilia formosa	44.71	0.00e+00	791.00
IUUC-Pab-098153	Pongo abelii	56.59	0.00e+00	679.00
IUUC-Pca-100957	Procavia capensis	55.90	0.00e+00	659.00
IUUC-Pva-102439	Pteropus vampyrus	47.74	0.00e+00	878.00
IUUC-Rno-105891	Rattus norvegicus	47.60	0.00e+00	846.00
IUUC-Sha-107181	Sarcophilus harrisii	50.69	0.00e+00	664.00
IUUC-Ssc-115413	Sus scrofa	49.95	0.00e+00	905.00
IUUC-Tgu-117082	Taeniopygia guttata	50.19	0.00e+00	880.00
IUUC-Tru-118491	Takifugu rubripes	56.07	3.00e-95	343.00
IUUC-Tsy-119629	Tarsius syrichta	53.01	5.00e-75	276.00
IUUC-Tni-120240	Tetraodon nigroviridis	43.31	2.00e-154	540.00
IUUC-Tbe-127673	Tupaia belangeri	53.85	1.00e-163	571.00
IUUC-Ttr-128562	Tursiops truncatus	48.81	0.00e+00	824.00
IUUC-Vpa-130596	Vicugna pacos	45.36	0.00e+00	760.00
IUUC-Xtr-132469	Xenopus tropicalis	54.84	0.00e+00	642.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence