iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028595

Ensembl Protein ID

ENSDARP00000109120.2

UniProt Accession

Q98TH2; Q98TH2_DANRE

Genbank Protein ID

AAI62571.1; BAB40698.1

Protein Name

Groucho 1; Groucho-related gene 3 protein; Transducin-like enhancer of split 3b

Genbank Nucleotide ID

AL954672; AB040707

Gene Name

tle3b; grg3; gro1; gro3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000069006.6	ENSDART00000130553.3	ENSDARP00000109120.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-21	77.0	615	653

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 615  GHTDGASCIDIsHDgTKLWTGGLDNTVRSWDLREGRQLQ 653
           8**********9888*********************998 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MYPQGRHPAP HQPGQPGFKF TVAESCDRIK DEFQFLQAQY HSLKVEYDKL ANEKTEMQRH 60
YVMYYEMSYG LNIEMHKQTE IAKRLNAILA QIMPFLSQEH QQQVAQAVER AKQVTMTELN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TACGAGGCAA ACTTTTCACC ATCAAACCAT TTTTAAACAA GCAATCAAAT AGGGATTGGG 60
AGAATTTATC AACACCCTGA GAACTGTGTT CAAGCAAGTC TTAACAGAGG AAAACAATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR027295--Quinoprotein_ADH-like_fam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

dre:100007463

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002200	Ailuropoda melanoleuca	90.71	0.00e+00	1261.00
IUUC-Apl-003594	Anas platyrhynchos	78.35	0.00e+00	1021.00
IUUC-Aca-005074	Anolis carolinensis	88.61	0.00e+00	976.00
IUUC-Ame-010724	Astyanax mexicanus	94.40	0.00e+00	1349.00
IUUC-Bta-013189	Bos taurus	90.26	0.00e+00	1257.00
IUUC-Cel-018361	Caenorhabditis elegans	58.71	3.00e-120	426.00
IUUC-Cja-018781	Callithrix jacchus	89.90	0.00e+00	1257.00
IUUC-Cfa-021016	Canis familiaris	88.10	0.00e+00	1152.00
IUUC-Cpo-021793	Cavia porcellus	90.45	0.00e+00	1254.00
IUUC-Csa-023928	Chlorocebus sabaeus	90.13	0.00e+00	1257.00
IUUC-Cho-024590	Choloepus hoffmanni	71.65	0.00e+00	991.00
IUUC-Cin-025282	Ciona intestinalis	72.80	1.00e-154	540.00
IUUC-Dno-029736	Dasypus novemcinctus	85.79	0.00e+00	955.00
IUUC-Dor-030533	Dipodomys ordii	77.52	0.00e+00	961.00
IUUC-Ete-032685	Echinops telfairi	87.28	0.00e+00	1169.00
IUUC-Eca-033249	Equus caballus	90.24	0.00e+00	1249.00
IUUC-Eeu-035237	Erinaceus europaeus	68.14	0.00e+00	947.00
IUUC-Fca-036239	Felis catus	88.46	0.00e+00	1125.00
IUUC-Fal-037460	Ficedula albicollis	80.18	0.00e+00	1109.00
IUUC-Gmo-039000	Gadus morhua	86.21	0.00e+00	1160.00
IUUC-Gga-040416	Gallus gallus	80.38	0.00e+00	1124.00
IUUC-Ggo-044458	Gorilla gorilla	89.99	0.00e+00	1286.00
IUUC-Hsa-046549	Homo sapiens	90.03	0.00e+00	1259.00
IUUC-Itr-048974	Ictidomys tridecemlineatus	80.51	0.00e+00	1129.00
IUUC-Lch-050110	Latimeria chalumnae	91.48	0.00e+00	1210.00
IUUC-Loc-052165	Lepisosteus oculatus	94.19	0.00e+00	1295.00
IUUC-Laf-053817	Loxodonta africana	89.00	0.00e+00	1260.00
IUUC-Mcc-055673	Macaca mulatta	90.41	0.00e+00	1274.00
IUUC-Meu-056601	Macropus eugenii	89.49	0.00e+00	1264.00
IUUC-Mga-059792	Meleagris gallopavo	81.16	0.00e+00	963.00
IUUC-Mmr-060904	Microcebus murinus	90.80	0.00e+00	1274.00
IUUC-Mdo-061897	Monodelphis domestica	88.11	0.00e+00	1244.00
IUUC-Mmu-063702	Mus musculus	90.55	0.00e+00	1242.00
IUUC-Mpu-066618	Mustela putorius furo	90.00	0.00e+00	1254.00
IUUC-Mlu-067934	Myotis lucifugus	90.19	0.00e+00	1254.00
IUUC-Nle-069452	Nomascus leucogenys	90.13	0.00e+00	1258.00
IUUC-Oan-072842	Ornithorhynchus anatinus	78.65	0.00e+00	1116.00
IUUC-Ocu-074091	Oryctolagus cuniculus	89.83	0.00e+00	1219.00
IUUC-Ola-086719	Oryzias latipes	90.93	0.00e+00	1283.00
IUUC-Oga-088548	Otolemur garnettii	89.54	0.00e+00	1266.00
IUUC-Oar-089856	Ovis aries	89.68	0.00e+00	1254.00
IUUC-Ptr-090848	Pan troglodytes	90.13	0.00e+00	1256.00
IUUC-Pan-092288	Papio anubis	90.71	0.00e+00	1264.00
IUUC-Psi-093427	Pelodiscus sinensis	90.48	0.00e+00	1238.00
IUUC-Pma-094452	Petromyzon marinus	79.39	0.00e+00	916.00
IUUC-Pfo-096880	Poecilia formosa	92.52	0.00e+00	1278.00
IUUC-Pab-098175	Pongo abelii	90.26	0.00e+00	1259.00
IUUC-Pca-100321	Procavia capensis	89.66	0.00e+00	1258.00
IUUC-Pva-102741	Pteropus vampyrus	83.27	0.00e+00	1135.00
IUUC-Rno-104864	Rattus norvegicus	90.58	0.00e+00	1250.00
IUUC-Sha-106568	Sarcophilus harrisii	92.13	0.00e+00	1267.00
IUUC-Sar-113414	Sorex araneus	92.97	5.00e-180	624.00
IUUC-Ssc-116160	Sus scrofa	89.39	0.00e+00	1253.00
IUUC-Tgu-117068	Taeniopygia guttata	80.45	0.00e+00	1120.00
IUUC-Tru-117982	Takifugu rubripes	89.70	0.00e+00	1295.00
IUUC-Tsy-118884	Tarsius syrichta	68.63	0.00e+00	899.00
IUUC-Ttr-128845	Tursiops truncatus	89.39	0.00e+00	1268.00
IUUC-Vpa-130577	Vicugna pacos	64.40	3.00e-136	479.00
IUUC-Xtr-132974	Xenopus tropicalis	79.05	0.00e+00	1079.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence