iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048228

Ensembl Protein ID

ENSSTOP00000003929.2

UniProt Accession

I3M445; I3M445_ICTTR

Genbank Protein ID

ENSSTOP00000003929

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01073290

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004353.2	ENSSTOT00000004379.2	ENSSTOP00000003929.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-16	59.0	51	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvW 28
           gH+dsv+c+a+  d ++++sGs D+++ +W
   Q: 51   GHKDSVYCVAYaKDgKRFASGSADKSVIIW 80
           8***********777*************** PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MRSVLTWKDK IDQCVYDLAF KPDGTQLILA AGNRLLVYDT SDGTLVQPLK GHKDSVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY TPPQVPLSPH LASSNALPQG MAPCPSVTSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGGTCCG TGCTGACGTG GAAAGATAAA ATCGATCAGT GGTGAGAAGC GGGGCAGTTG 60
GGGAGGAGCG GGAGGCCGAG CCCGGGAGGG GATGGCGGGA GCCACTCCTG TGAGCCCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	83.43	0.00e+00	2025.00
IUUC-Apl-003504	Anas platyrhynchos	74.41	0.00e+00	1808.00
IUUC-Aca-004767	Anolis carolinensis	75.49	0.00e+00	1854.00
IUUC-Ame-011642	Astyanax mexicanus	65.86	0.00e+00	1593.00
IUUC-Bta-012969	Bos taurus	81.68	0.00e+00	1949.00
IUUC-Cel-018670	Caenorhabditis elegans	38.29	0.00e+00	734.00
IUUC-Cja-019249	Callithrix jacchus	75.72	0.00e+00	1807.00
IUUC-Cfa-020915	Canis familiaris	83.18	0.00e+00	1962.00
IUUC-Cpo-021888	Cavia porcellus	74.84	0.00e+00	1620.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	49.45	0.00e+00	964.00
IUUC-Csa-023533	Chlorocebus sabaeus	81.33	0.00e+00	1955.00
IUUC-Cin-025121	Ciona intestinalis	54.67	0.00e+00	1220.00
IUUC-Csv-026240	Ciona savignyi	54.07	0.00e+00	1279.00
IUUC-Dno-029685	Dasypus novemcinctus	87.01	0.00e+00	1647.00
IUUC-Dme-032005	Drosophila melanogaster	25.23	3.00e-08	54.30
IUUC-Ete-032682	Echinops telfairi	80.35	0.00e+00	1499.00
IUUC-Eca-033831	Equus caballus	83.13	0.00e+00	2013.00
IUUC-Eeu-034919	Erinaceus europaeus	78.11	0.00e+00	766.00
IUUC-Fca-036559	Felis catus	82.34	0.00e+00	2001.00
IUUC-Fal-037340	Ficedula albicollis	73.08	0.00e+00	1800.00
IUUC-Gga-040595	Gallus gallus	73.86	0.00e+00	1819.00
IUUC-Ggo-045356	Gorilla gorilla	82.84	0.00e+00	2019.00
IUUC-Hsa-046135	Homo sapiens	82.94	0.00e+00	2019.00
IUUC-Lch-050183	Latimeria chalumnae	74.96	0.00e+00	937.00
IUUC-Loc-052049	Lepisosteus oculatus	70.06	0.00e+00	1724.00
IUUC-Laf-053728	Loxodonta africana	82.86	0.00e+00	2032.00
IUUC-Mcc-054971	Macaca mulatta	83.21	0.00e+00	2019.00
IUUC-Meu-056446	Macropus eugenii	78.75	0.00e+00	1899.00
IUUC-Mga-059296	Meleagris gallopavo	75.81	0.00e+00	1875.00
IUUC-Mmr-061232	Microcebus murinus	83.33	0.00e+00	2009.00
IUUC-Mdo-062115	Monodelphis domestica	81.60	0.00e+00	1985.00
IUUC-Mmu-063664	Mus musculus	81.75	0.00e+00	2003.00
IUUC-Mpu-066136	Mustela putorius furo	79.45	0.00e+00	1912.00
IUUC-Mlu-068238	Myotis lucifugus	79.25	0.00e+00	1914.00
IUUC-Nle-069003	Nomascus leucogenys	77.19	0.00e+00	1845.00
IUUC-Ont-072080	Oreochromis niloticus	67.52	0.00e+00	1678.00
IUUC-Oan-072891	Ornithorhynchus anatinus	78.14	0.00e+00	856.00
IUUC-Ocu-074262	Oryctolagus cuniculus	80.47	0.00e+00	1966.00
IUUC-Ola-086538	Oryzias latipes	66.13	0.00e+00	1647.00
IUUC-Oga-088722	Otolemur garnettii	84.67	0.00e+00	1997.00
IUUC-Oar-089249	Ovis aries	86.69	0.00e+00	1641.00
IUUC-Ptr-090752	Pan troglodytes	81.28	0.00e+00	1965.00
IUUC-Pan-092472	Papio anubis	81.26	0.00e+00	1961.00
IUUC-Psi-093335	Pelodiscus sinensis	75.00	0.00e+00	1837.00
IUUC-Pma-094520	Petromyzon marinus	65.11	0.00e+00	1459.00
IUUC-Ppa-095600	Physcomitrella patens	57.73	3.00e-31	126.00
IUUC-Pfo-096526	Poecilia formosa	62.92	0.00e+00	1552.00
IUUC-Pab-098428	Pongo abelii	73.79	0.00e+00	1524.00
IUUC-Pca-100233	Procavia capensis	68.61	0.00e+00	974.00
IUUC-Pva-103064	Pteropus vampyrus	74.05	0.00e+00	1735.00
IUUC-Rno-105764	Rattus norvegicus	82.02	0.00e+00	2023.00
IUUC-Sha-106649	Sarcophilus harrisii	81.10	0.00e+00	1965.00
IUUC-Smo-109478	Selaginella moellendorffii	40.63	0.00e+00	666.00
IUUC-Tgu-116870	Taeniopygia guttata	73.04	0.00e+00	1748.00
IUUC-Tru-118661	Takifugu rubripes	65.64	0.00e+00	1627.00
IUUC-Tsy-119640	Tarsius syrichta	88.06	3.00e-106	379.00
IUUC-Tni-120812	Tetraodon nigroviridis	63.09	0.00e+00	1524.00
IUUC-Ttr-128862	Tursiops truncatus	83.77	0.00e+00	2021.00
IUUC-Vpa-130049	Vicugna pacos	72.13	0.00e+00	1024.00
IUUC-Xtr-131914	Xenopus tropicalis	72.66	0.00e+00	1589.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence