iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053728

Ensembl Protein ID

ENSLAFP00000008888.3

UniProt Accession

G3T5Y8; G3T5Y8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

IFT122

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010612.3	ENSLAFT00000030570.1	ENSLAFP00000018949.1
ENSLAFG00000010612.3	ENSLAFT00000010616.3	ENSLAFP00000008888.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-16	58.7	52	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvW 28
           H+d v+c+a+  d ++++sGs D+++ +W
   Q: 52   HKDTVYCVAYaKDgKRFASGSADKSVIIW 80
           ***********777*************** PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MRAVLTWRDK AEQCVYDLAF KPDGTQLILA AGNRLLVYDT SDGTLLQPLK AHKDTVYCVA 60
YAKDGKRFAS GSADKSVIIW TSKLEGILKY THSDSIQCVS YNPVTHQLAS CSSNDFGLWS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCGGAGT GGGGCCTGTT GCTGAGGCGG GGAGGAGGGG CCCGAGGCGA GAGGGAAGCC 60
GCGATGAGGG CCGTGTTGAC GTGGAGAGAT AAAGCCGAGC AGTGGTGAGG AGAGGGGCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0036064--C:ciliary basal body
GO:0097546--C:ciliary base
GO:0005829--C:cytosol
GO:0030991--C:intraciliary transport particle A
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0032391--C:photoreceptor connecting cilium
GO:0048593--P:camera-type eye morphogenesis
GO:0060830--P:ciliary receptor clustering involved in smoothened signaling pathway
GO:0010172--P:embryonic body morphogenesis
GO:0042733--P:embryonic digit morphogenesis
GO:0035115--P:embryonic forelimb morphogenesis
GO:0060971--P:embryonic heart tube left/right pattern formation
GO:0072594--P:establishment of protein localization to organelle
GO:0035720--P:intraciliary anterograde transport
GO:0035721--P:intraciliary retrograde transport
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0021914--P:negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0001843--P:neural tube closure
GO:1905515--P:non-motile cilium assembly
GO:0061512--P:protein localization to cilium
GO:0007227--P:signal transduction downstream of smoothened
GO:0060831--P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001933	Ailuropoda melanoleuca	96.22	0.00e+00	2363.00
IUUC-Apl-003504	Anas platyrhynchos	90.26	0.00e+00	1868.00
IUUC-Aca-004767	Anolis carolinensis	85.82	0.00e+00	2167.00
IUUC-Ame-011642	Astyanax mexicanus	75.48	0.00e+00	1932.00
IUUC-Bta-012969	Bos taurus	94.29	0.00e+00	2303.00
IUUC-Cel-018670	Caenorhabditis elegans	38.38	0.00e+00	890.00
IUUC-Cja-019249	Callithrix jacchus	86.66	0.00e+00	2127.00
IUUC-Cfa-020915	Canis familiaris	96.06	0.00e+00	2316.00
IUUC-Cpo-021888	Cavia porcellus	77.92	0.00e+00	1937.00
IUUC-Cre-022789	Chlamydomonas reinhardtii	48.74	0.00e+00	1120.00
IUUC-Csa-023533	Chlorocebus sabaeus	91.79	0.00e+00	2271.00
IUUC-Cin-025121	Ciona intestinalis	58.45	0.00e+00	1511.00
IUUC-Csv-026240	Ciona savignyi	59.47	0.00e+00	1460.00
IUUC-Dno-029685	Dasypus novemcinctus	90.35	0.00e+00	2216.00
IUUC-Dme-032005	Drosophila melanogaster	25.86	7.00e-08	53.10
IUUC-Ete-032682	Echinops telfairi	86.73	0.00e+00	1717.00
IUUC-Eca-033831	Equus caballus	96.38	0.00e+00	2404.00
IUUC-Eeu-034919	Erinaceus europaeus	86.87	0.00e+00	1025.00
IUUC-Fca-036559	Felis catus	95.25	0.00e+00	2365.00
IUUC-Fal-037340	Ficedula albicollis	87.53	0.00e+00	1775.00
IUUC-Gga-040595	Gallus gallus	76.11	0.00e+00	1902.00
IUUC-Ggo-045356	Gorilla gorilla	87.93	0.00e+00	2235.00
IUUC-Hsa-046135	Homo sapiens	87.79	0.00e+00	2234.00
IUUC-Itr-048228	Ictidomys tridecemlineatus	82.59	0.00e+00	1972.00
IUUC-Lch-050183	Latimeria chalumnae	83.36	0.00e+00	1196.00
IUUC-Loc-052049	Lepisosteus oculatus	80.18	0.00e+00	2033.00
IUUC-Mcc-054971	Macaca mulatta	88.79	0.00e+00	2251.00
IUUC-Meu-056446	Macropus eugenii	85.75	0.00e+00	2185.00
IUUC-Mga-059296	Meleagris gallopavo	81.37	0.00e+00	2110.00
IUUC-Mmr-061232	Microcebus murinus	91.77	0.00e+00	2278.00
IUUC-Mdo-062115	Monodelphis domestica	93.40	0.00e+00	2334.00
IUUC-Mmu-063664	Mus musculus	93.32	0.00e+00	2367.00
IUUC-Mpu-066136	Mustela putorius furo	92.37	0.00e+00	2286.00
IUUC-Mlu-068238	Myotis lucifugus	91.55	0.00e+00	2298.00
IUUC-Nle-069003	Nomascus leucogenys	88.11	0.00e+00	2157.00
IUUC-Ont-072080	Oreochromis niloticus	76.22	0.00e+00	1960.00
IUUC-Oan-072891	Ornithorhynchus anatinus	82.82	0.00e+00	910.00
IUUC-Ocu-074262	Oryctolagus cuniculus	92.28	0.00e+00	2269.00
IUUC-Ola-086538	Oryzias latipes	72.35	0.00e+00	1841.00
IUUC-Oga-088722	Otolemur garnettii	90.48	0.00e+00	2234.00
IUUC-Oar-089249	Ovis aries	89.06	0.00e+00	2192.00
IUUC-Ptr-090752	Pan troglodytes	91.06	0.00e+00	2074.00
IUUC-Pan-092472	Papio anubis	91.80	0.00e+00	2275.00
IUUC-Psi-093335	Pelodiscus sinensis	84.31	0.00e+00	2121.00
IUUC-Pma-094520	Petromyzon marinus	65.17	0.00e+00	1508.00
IUUC-Ppa-095600	Physcomitrella patens	61.06	4.00e-39	153.00
IUUC-Pfo-096526	Poecilia formosa	72.56	0.00e+00	1812.00
IUUC-Pab-098428	Pongo abelii	89.31	0.00e+00	1100.00
IUUC-Pca-100233	Procavia capensis	72.33	0.00e+00	971.00
IUUC-Pva-103064	Pteropus vampyrus	82.53	0.00e+00	2005.00
IUUC-Rno-105764	Rattus norvegicus	93.97	0.00e+00	2348.00
IUUC-Sha-106649	Sarcophilus harrisii	93.50	0.00e+00	2321.00
IUUC-Smo-109287	Selaginella moellendorffii	39.31	0.00e+00	870.00
IUUC-Tgu-116870	Taeniopygia guttata	84.19	0.00e+00	2058.00
IUUC-Tru-118661	Takifugu rubripes	71.24	0.00e+00	1814.00
IUUC-Tsy-119640	Tarsius syrichta	75.98	0.00e+00	658.00
IUUC-Tni-120812	Tetraodon nigroviridis	72.94	0.00e+00	1830.00
IUUC-Ttr-128862	Tursiops truncatus	91.94	0.00e+00	2345.00
IUUC-Vpa-130049	Vicugna pacos	86.79	1.00e-153	537.00
IUUC-Xtr-131914	Xenopus tropicalis	79.36	0.00e+00	2009.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence