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Tag Content
UUCD2 ID IUUC-Mga-059875
UUCD1 version UUC-MeG-00219
Ensembl Protein ID ENSMGAP00000004213.2
UniProt Accession G1MYZ2; G1MYZ2_MELGA
Protein Name Coatomer subunit beta'
Gene Name COPB2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMGAG00000004383.2 ENSMGAT00000004926.2 ENSMGAP00000004213.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.80e-34 115.4 185 226
UBD/Beta-Prp 1.10e-70 238.0 13 294
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 185  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 226
           8*********9999778****************999988875 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgheds 96
           ++++++++v+ +p +++++++ ++g++ vw+ +t++l+++++ ++ +v+a kf  ++++ vtg++D+ i+v++++t + vh +++h+d+
   Q: 13   ARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDY 101
           67899************************************************************************************ PP
   S: 97   vlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpd..g.nllvsGslDrtvrlWdlktgkllrtltgghtds 182
           +++++++p++ ++++ s+d  i++wd+++++  +++++gh++ v+ +v++p+  + n ++s+slDrt+++W+l + +   tl+g h++ 
   Q: 102  IRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKxkDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKG 189
           *******************************9999**************98533349**************************9.**** PP
   S: 183  vyslsfdsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           v+++++ s g  ++l+sg++d+ vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++
   Q: 190  VNCIDYYSGGdkPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWC 278
           *****8887777***************************************************************************** PP
   S: 270  vavlsfgdnvlvlgse 285
           va l+ ++nv +  +e
   Q: 279  VASLRGSNNVALGYDE 294
           ***9999998755544 PP
   
Organism Meleagris gallopavo
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKRK LTARSDRVKS VDLHPTEPWM LASLYNGSVC VWNHETQTLV KTFEVCDLPV 60
RAAKFVARKN WVVTGADDMQ IRVFNYNTLE RVHMFEAHSD YIRCIAVHPT QPFILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mga-059875|E3,WD_repeat;UBD,Beta-Prp|Meleagris gallopavo
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGCTGCCGG GCCTGGGACA CCTCAGCAGC GGGGCTCCTG CGGGGTGACG CCGCGCCATG 60
GTGAGTGAGT GCGGGAGCGC GGCGTCCGCG AAGAGCGGAG TGGGCCGTGT GACGCGGTGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mga-059875|E3,WD_repeat;UBD,Beta-Prp|Meleagris gallopavo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:1901998--P:toxin transport
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 52.53 0.00e+00 943.00
IUUC-Aml-002154 Ailuropoda melanoleuca 93.00 0.00e+00 1734.00
IUUC-Atr-003090 Amborella trichopoda 59.31 0.00e+00 1081.00
IUUC-Apl-003976 Anas platyrhynchos 98.30 0.00e+00 1810.00
IUUC-Aca-004301 Anolis carolinensis 95.61 0.00e+00 1724.00
IUUC-Aly-006508 Arabidopsis lyrata 60.57 0.00e+00 1095.00
IUUC-Ath-007630 Arabidopsis thaliana 61.79 0.00e+00 1105.00
IUUC-Ago-007914 Ashbya gossypii 46.20 0.00e+00 755.00
IUUC-Acl-008237 Aspergillus clavatus 54.49 0.00e+00 963.00
IUUC-Afl-008535 Aspergillus flavus 55.67 0.00e+00 910.00
IUUC-Afu-008845 Aspergillus fumigatus 54.04 0.00e+00 937.00
IUUC-Ani-009135 Aspergillus nidulans 55.81 0.00e+00 913.00
IUUC-Ang-009654 Aspergillus niger 56.02 0.00e+00 858.00
IUUC-Aor-009939 Aspergillus oryzae 53.29 0.00e+00 968.00
IUUC-Ate-010355 Aspergillus terreus 54.08 0.00e+00 915.00
IUUC-Ame-010922 Astyanax mexicanus 85.68 0.00e+00 1506.00
IUUC-Bgr-012249 Blumeria graminis 53.37 0.00e+00 932.00
IUUC-Bta-013579 Bos taurus 97.76 0.00e+00 1466.00
IUUC-Bci-013866 Botrytis cinerea 55.34 0.00e+00 929.00
IUUC-Bdi-015046 Brachypodium distachyon 61.54 0.00e+00 1112.00
IUUC-Bol-016271 Brassica oleracea 60.57 0.00e+00 1112.00
IUUC-Bra-016617 Brassica rapa 61.07 0.00e+00 1080.00
IUUC-Cel-018387 Caenorhabditis elegans 66.79 0.00e+00 1181.00
IUUC-Cja-019145 Callithrix jacchus 93.33 0.00e+00 1741.00
IUUC-Cfa-020564 Canis familiaris 93.33 0.00e+00 1736.00
IUUC-Cpo-022201 Cavia porcellus 94.63 0.00e+00 1727.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 58.65 0.00e+00 986.00
IUUC-Csa-023383 Chlorocebus sabaeus 97.01 0.00e+00 1167.00
IUUC-Cho-024454 Choloepus hoffmanni 91.04 0.00e+00 1390.00
IUUC-Cin-025681 Ciona intestinalis 76.71 0.00e+00 1370.00
IUUC-Csv-026012 Ciona savignyi 76.71 0.00e+00 1341.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 52.33 0.00e+00 850.00
IUUC-Cne-026986 Cryptococcus neoformans 51.20 0.00e+00 912.00
IUUC-Cme-027219 Cyanidioschyzon merolae 48.33 0.00e+00 847.00
IUUC-Dre-027846 Danio rerio 94.02 0.00e+00 1695.00
IUUC-Dor-030462 Dipodomys ordii 91.75 0.00e+00 1260.00
IUUC-Dse-031268 Dothistroma septosporum 54.96 0.00e+00 950.00
IUUC-Dme-031791 Drosophila melanogaster 69.67 0.00e+00 1274.00
IUUC-Ete-033166 Echinops telfairi 87.50 0.00e+00 1003.00
IUUC-Eca-034180 Equus caballus 92.74 0.00e+00 1670.00
IUUC-Eeu-035086 Erinaceus europaeus 82.48 0.00e+00 852.00
IUUC-Fca-036265 Felis catus 93.01 0.00e+00 1738.00
IUUC-Fal-037202 Ficedula albicollis 97.78 0.00e+00 1742.00
IUUC-Fox-037711 Fusarium oxysporum 56.32 0.00e+00 884.00
IUUC-Fso-038268 Fusarium solani 56.06 0.00e+00 884.00
IUUC-Gmo-039046 Gadus morhua 93.26 0.00e+00 1666.00
IUUC-Ggr-039863 Gaeumannomyces graminis 55.47 0.00e+00 906.00
IUUC-Gga-041112 Gallus gallus 99.10 0.00e+00 1826.00
IUUC-Gac-041733 Gasterosteus aculeatus 93.40 0.00e+00 1629.00
IUUC-Gma-044333 Glycine max 62.80 0.00e+00 1120.00
IUUC-Ggo-044984 Gorilla gorilla 93.01 0.00e+00 1736.00
IUUC-Hsa-046698 Homo sapiens 93.01 0.00e+00 1737.00
IUUC-Hvu-047669 Hordeum vulgare 70.79 5.00e-168 583.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 93.01 0.00e+00 1729.00
IUUC-Kpa-049265 Komagataella pastoris 49.32 0.00e+00 862.00
IUUC-Lch-050473 Latimeria chalumnae 91.64 0.00e+00 1730.00
IUUC-Lpe-051579 Leersia perrieri 61.38 0.00e+00 1102.00
IUUC-Loc-052675 Lepisosteus oculatus 94.09 0.00e+00 1709.00
IUUC-Lma-053218 Leptosphaeria maculans 54.16 0.00e+00 920.00
IUUC-Laf-053757 Loxodonta africana 92.90 0.00e+00 1731.00
IUUC-Mcc-054859 Macaca mulatta 93.44 0.00e+00 1743.00
IUUC-Meu-056174 Macropus eugenii 94.74 0.00e+00 743.00
IUUC-Mor-057264 Magnaporthe oryzae 55.53 0.00e+00 885.00
IUUC-Mpo-057538 Magnaporthe poae 55.84 0.00e+00 920.00
IUUC-Mtr-058310 Medicago truncatula 62.80 0.00e+00 1130.00
IUUC-Mla-058937 Melampsora laricipopulina 53.55 0.00e+00 913.00
IUUC-Mvi-060240 Microbotryum violaceum 49.30 0.00e+00 908.00
IUUC-Mmr-061261 Microcebus murinus 93.66 0.00e+00 1750.00
IUUC-Mdo-062076 Monodelphis domestica 95.11 0.00e+00 1751.00
IUUC-Mmu-063324 Mus musculus 93.11 0.00e+00 1739.00
IUUC-Mac-064636 Musa acuminata 60.51 0.00e+00 1091.00
IUUC-Mpu-065961 Mustela putorius furo 93.22 0.00e+00 1738.00
IUUC-Mlu-067059 Myotis lucifugus 94.05 0.00e+00 1673.00
IUUC-Nfi-068277 Neosartorya fischeri 54.62 0.00e+00 926.00
IUUC-Ncr-068659 Neurospora crassa 52.82 0.00e+00 912.00
IUUC-Nle-069034 Nomascus leucogenys 93.33 0.00e+00 1743.00
IUUC-Opr-070334 Ochotona princeps 97.15 0.00e+00 1503.00
IUUC-Ont-071563 Oreochromis niloticus 93.76 0.00e+00 1682.00
IUUC-Oan-073416 Ornithorhynchus anatinus 97.21 0.00e+00 1652.00
IUUC-Ocu-074522 Oryctolagus cuniculus 93.55 0.00e+00 1741.00
IUUC-Oba-075760 Oryza barthii 59.05 0.00e+00 1084.00
IUUC-Obr-076201 Oryza brachyantha 61.47 0.00e+00 1108.00
IUUC-Ogl-077450 Oryza glaberrima 60.21 0.00e+00 1112.00
IUUC-Ogu-078994 Oryza glumaepatula 59.05 0.00e+00 1083.00
IUUC-Oin-079856 Oryza indica 60.50 0.00e+00 1084.00
IUUC-Olo-080731 Oryza longistaminata 58.38 0.00e+00 1068.00
IUUC-Ome-081762 Oryza meridionalis 56.89 0.00e+00 1004.00
IUUC-Oni-082324 Oryza nivara 59.05 0.00e+00 1084.00
IUUC-Opu-083400 Oryza punctata 59.10 0.00e+00 1073.00
IUUC-Oru-084829 Oryza rufipogon 59.05 0.00e+00 1084.00
IUUC-Osa-086026 Oryza sativa 60.21 0.00e+00 1115.00
IUUC-Ola-087245 Oryzias latipes 91.63 0.00e+00 1681.00
IUUC-Olu-087655 Ostreococcus lucimarinus 59.95 0.00e+00 1053.00
IUUC-Oga-088163 Otolemur garnettii 90.28 0.00e+00 1670.00
IUUC-Oar-089842 Ovis aries 94.29 0.00e+00 1725.00
IUUC-Ptr-090501 Pan troglodytes 93.22 0.00e+00 1739.00
IUUC-Pan-092011 Papio anubis 93.44 0.00e+00 1743.00
IUUC-Psi-093308 Pelodiscus sinensis 95.37 0.00e+00 1745.00
IUUC-Pma-094695 Petromyzon marinus 80.97 0.00e+00 1443.00
IUUC-Pno-094785 Phaeosphaeria nodorum 61.64 8.00e-111 394.00
IUUC-Ppa-095911 Physcomitrella patens 62.12 0.00e+00 1132.00
IUUC-Pfo-096587 Poecilia formosa 90.43 0.00e+00 1687.00
IUUC-Pab-097926 Pongo abelii 90.65 0.00e+00 1645.00
IUUC-Pop-099634 Populus trichocarpa 62.20 0.00e+00 1107.00
IUUC-Pca-100965 Procavia capensis 91.90 0.00e+00 1690.00
IUUC-Ppe-101470 Prunus persica 62.68 0.00e+00 1120.00
IUUC-Pva-102451 Pteropus vampyrus 90.85 0.00e+00 1251.00
IUUC-Pgr-103453 Puccinia graminis 53.71 0.00e+00 928.00
IUUC-Ptt-103868 Puccinia triticina 54.42 0.00e+00 924.00
IUUC-Pte-104274 Pyrenophora teres 54.95 0.00e+00 952.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 54.39 0.00e+00 901.00
IUUC-Rno-105979 Rattus norvegicus 83.22 0.00e+00 1246.00
IUUC-Sce-106269 Saccharomyces cerevisiae 47.18 0.00e+00 778.00
IUUC-Sha-106905 Sarcophilus harrisii 95.74 0.00e+00 1740.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 47.22 0.00e+00 828.00
IUUC-Spo-108299 Schizosaccharomyces pombe 47.29 0.00e+00 828.00
IUUC-Smo-108695 Selaginella moellendorffii 61.81 0.00e+00 1078.00
IUUC-Sit-110692 Setaria italica 62.56 0.00e+00 1108.00
IUUC-Sly-111775 Solanum lycopersicum 60.52 0.00e+00 1096.00
IUUC-Stu-112906 Solanum tuberosum 60.40 0.00e+00 991.00
IUUC-Sar-113472 Sorex araneus 89.68 0.00e+00 1141.00
IUUC-Sbi-113801 Sorghum bicolor 60.39 0.00e+00 1110.00
IUUC-Sre-115040 Sporisorium reilianum 52.28 0.00e+00 915.00
IUUC-Ssc-115593 Sus scrofa 93.55 0.00e+00 1744.00
IUUC-Tgu-117239 Taeniopygia guttata 97.73 0.00e+00 1799.00
IUUC-Tru-118025 Takifugu rubripes 93.53 0.00e+00 1673.00
IUUC-Tsy-118824 Tarsius syrichta 89.21 0.00e+00 1154.00
IUUC-Tni-120142 Tetraodon nigroviridis 91.77 0.00e+00 1673.00
IUUC-Tca-121613 Theobroma cacao 61.84 0.00e+00 1110.00
IUUC-Tre-122072 Trichoderma reesei 55.35 0.00e+00 933.00
IUUC-Tvi-122546 Trichoderma virens 54.86 0.00e+00 919.00
IUUC-Tae-125292 Triticum aestivum 60.66 0.00e+00 1103.00
IUUC-Tur-126283 Triticum urartu 53.36 0.00e+00 942.00
IUUC-Tme-127041 Tuber melanosporum 55.49 0.00e+00 974.00
IUUC-Tbe-127770 Tupaia belangeri 90.99 0.00e+00 1256.00
IUUC-Ttr-129294 Tursiops truncatus 93.33 0.00e+00 1739.00
IUUC-Uma-129351 Ustilago maydis 50.71 0.00e+00 905.00
IUUC-Vda-129716 Verticillium dahliae 55.35 0.00e+00 952.00
IUUC-Vpa-130037 Vicugna pacos 82.94 0.00e+00 877.00
IUUC-Vvi-131689 Vitis vinifera 61.47 0.00e+00 1114.00
IUUC-Xtr-132633 Xenopus tropicalis 93.03 0.00e+00 1693.00
IUUC-Xma-133347 Xiphophorus maculatus 92.05 0.00e+00 1687.00
IUUC-Yli-134455 Yarrowia lipolytica 50.51 0.00e+00 838.00
IUUC-Zma-135706 Zea mays 60.96 0.00e+00 1130.00
Created Date 25-Jun-2017

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