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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Spo-108299
UUCD1 version UUC-ScP-00086
Ensembl Protein ID SPBC16C6.13c.1:pep
UniProt Accession O42937; COPB2_SCHPO
Genbank Protein ID CAA16920.1
Protein Name Probable coatomer subunit beta'; Beta'-coat protein
Genbank Nucleotide ID CU329671
Gene Name sec27; SPBC16C6.13c; SPBC244.03
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
SPBC16C6.13c SPBC16C6.13c.1 SPBC16C6.13c.1:pep
Annotation
mRNA Expression
GEO
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-30 101.5 183 221
UBD/Beta-Prp 3.30e-66 221.5 12 303
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvll 36
           H  +v+ +++    d ++l++++dD+ ikvWD+ t  ++
   Q: 183  HDRGVNYVNYypaGDkPYLITAGDDNLIKVWDYQTKACV 221
           88999999988*9778****************9988776 PP
   

   UBD/Beta-Prp
   S: 8    hhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           +h++++++v+f+p +++++++ ++g + +w++ t++l+rs+  ++ +++a+ f+ +++++v gs+D  ++v++++tg+ v  +++h d+++
   Q: 12   SHTERVKAVDFHPTEPWVIASHYNGQVGIWNYNTQTLVRSFDINDVPIRACAFIARKNWFVCGSDDFQVRVYNYNTGEKVTQFEAHPDYIR 102
           69999************************************************************************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsf 188
           +l ++p++ +l++ s+d ti++++++  ++  +t++gh++ v++++++p++ n ++s++lD+tv++W+  +     tl+  h++ v+ +++
   Q: 103  ALVVHPTQPFLLTSSDDMTIKCFNWDMSWKCVQTFEGHSRYVMSLAINPKDtNTFASSCLDGTVKVWSFGSSVANFTLQA-HDRGVNYVNY 192
           **********************88887776666**********************************8877777788887.*********9 PP
   S: 189  dsng..kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgd 277
            + g  ++l+++++d+ +k+wd+qt+ cvr+l+ght+nv+   f+++  +++sgs+Dg+++iW + s  l+k+++ + ++ +++a    +d
   Q: 193  YPAGdkPYLITAGDDNLIKVWDYQTKACVRILEGHTNNVSFAFFHSKFPIIISGSEDGTVKIWHTLSYSLIKSYNFSLDRAWCIAQ--NKD 281
           998888*******************************************************************************9..99* PP
   S: 278  nvlvlgsedskvniwklkknep 299
           n lv++++d+ + +++l ++ep
   Q: 282  NGLVTVGFDNGLITFSLGRDEP 303
           *********9999999877765 PP
   
Organism Schizosaccharomyces pombe
Functional Description
(View)

Functional Description


     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
 The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
Protein Sequence
(Fasta)
MMRLDFQRKL LSHTERVKAV DFHPTEPWVI ASHYNGQVGI WNYNTQTLVR SFDINDVPIR 60
ACAFIARKNW FVCGSDDFQV RVYNYNTGEK VTQFEAHPDY IRALVVHPTQ PFLLTSSDDM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Spo-108299|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGATGCGTAT TTCCTTTCAC TGTGGAATCG ACACTACCAG TTCACTACAC CCTCTGCCAA 60
TACTAAATAG GACCATATAG CCGAAACTGG CATAATAAGG CTTCTGTTAA ATATTTAATA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Spo-108299|E3,WD_repeat;UBD,Beta-Prp|Schizosaccharomyces pombe
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04053--Coatomer_WDAD
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER
KEGG spo:SPBC16C6.13c
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000654 Aegilops tauschii 39.04 0.00e+00 658.00
IUUC-Aml-002154 Ailuropoda melanoleuca 47.66 0.00e+00 837.00
IUUC-Atr-003090 Amborella trichopoda 47.52 0.00e+00 783.00
IUUC-Apl-003976 Anas platyrhynchos 47.41 0.00e+00 833.00
IUUC-Aca-004301 Anolis carolinensis 47.53 0.00e+00 839.00
IUUC-Aly-005643 Arabidopsis lyrata 47.84 0.00e+00 783.00
IUUC-Ath-007635 Arabidopsis thaliana 46.97 0.00e+00 795.00
IUUC-Ago-007914 Ashbya gossypii 45.74 0.00e+00 753.00
IUUC-Acl-008237 Aspergillus clavatus 53.09 0.00e+00 902.00
IUUC-Afl-008535 Aspergillus flavus 52.96 0.00e+00 867.00
IUUC-Afu-008845 Aspergillus fumigatus 53.09 0.00e+00 885.00
IUUC-Ani-009135 Aspergillus nidulans 53.61 0.00e+00 878.00
IUUC-Ang-009654 Aspergillus niger 54.71 0.00e+00 812.00
IUUC-Aor-009939 Aspergillus oryzae 53.09 0.00e+00 916.00
IUUC-Ate-010355 Aspergillus terreus 53.72 0.00e+00 883.00
IUUC-Ame-010922 Astyanax mexicanus 42.84 0.00e+00 721.00
IUUC-Bgr-012249 Blumeria graminis 52.93 0.00e+00 870.00
IUUC-Bta-013579 Bos taurus 47.20 0.00e+00 759.00
IUUC-Bci-013866 Botrytis cinerea 53.59 0.00e+00 850.00
IUUC-Bdi-015046 Brachypodium distachyon 46.20 0.00e+00 785.00
IUUC-Bol-016271 Brassica oleracea 46.72 0.00e+00 801.00
IUUC-Bra-017576 Brassica rapa 46.72 0.00e+00 795.00
IUUC-Cel-018387 Caenorhabditis elegans 44.40 0.00e+00 771.00
IUUC-Cja-019145 Callithrix jacchus 47.66 0.00e+00 838.00
IUUC-Cfa-020564 Canis familiaris 47.66 0.00e+00 838.00
IUUC-Cpo-022201 Cavia porcellus 47.66 0.00e+00 837.00
IUUC-Cre-022938 Chlamydomonas reinhardtii 46.39 0.00e+00 745.00
IUUC-Csa-023383 Chlorocebus sabaeus 49.82 0.00e+00 653.00
IUUC-Cho-024454 Choloepus hoffmanni 44.34 0.00e+00 724.00
IUUC-Cin-025681 Ciona intestinalis 47.16 0.00e+00 776.00
IUUC-Csv-026012 Ciona savignyi 48.39 0.00e+00 777.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 49.81 0.00e+00 784.00
IUUC-Cne-026986 Cryptococcus neoformans 48.29 0.00e+00 832.00
IUUC-Cme-027219 Cyanidioschyzon merolae 41.13 0.00e+00 691.00
IUUC-Dre-027846 Danio rerio 46.65 0.00e+00 828.00
IUUC-Dor-030462 Dipodomys ordii 45.03 0.00e+00 657.00
IUUC-Dse-031268 Dothistroma septosporum 52.32 0.00e+00 899.00
IUUC-Dme-031791 Drosophila melanogaster 43.99 0.00e+00 763.00
IUUC-Ete-033166 Echinops telfairi 44.34 9.00e-158 548.00
IUUC-Eca-034180 Equus caballus 46.09 0.00e+00 791.00
IUUC-Eeu-035086 Erinaceus europaeus 36.53 1.00e-80 292.00
IUUC-Fca-036265 Felis catus 47.66 0.00e+00 837.00
IUUC-Fal-037202 Ficedula albicollis 46.73 0.00e+00 791.00
IUUC-Fox-037711 Fusarium oxysporum 53.97 0.00e+00 823.00
IUUC-Fso-038268 Fusarium solani 53.58 0.00e+00 819.00
IUUC-Gmo-039046 Gadus morhua 46.52 0.00e+00 822.00
IUUC-Ggr-039863 Gaeumannomyces graminis 54.22 0.00e+00 852.00
IUUC-Gga-041112 Gallus gallus 47.41 0.00e+00 833.00
IUUC-Gac-041733 Gasterosteus aculeatus 46.08 0.00e+00 795.00
IUUC-Gma-042910 Glycine max 46.72 0.00e+00 803.00
IUUC-Ggo-044984 Gorilla gorilla 47.66 0.00e+00 837.00
IUUC-Hsa-046698 Homo sapiens 47.53 0.00e+00 837.00
IUUC-Hvu-047669 Hordeum vulgare 53.26 4.00e-124 435.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 47.66 0.00e+00 836.00
IUUC-Kpa-049265 Komagataella pastoris 50.69 0.00e+00 857.00
IUUC-Lch-050473 Latimeria chalumnae 47.16 0.00e+00 831.00
IUUC-Lpe-051579 Leersia perrieri 46.81 0.00e+00 782.00
IUUC-Loc-052675 Lepisosteus oculatus 46.90 0.00e+00 830.00
IUUC-Lma-053218 Leptosphaeria maculans 51.77 0.00e+00 855.00
IUUC-Laf-053757 Loxodonta africana 47.41 0.00e+00 830.00
IUUC-Mcc-054859 Macaca mulatta 47.66 0.00e+00 838.00
IUUC-Meu-056174 Macropus eugenii 39.08 3.00e-70 258.00
IUUC-Mor-057264 Magnaporthe oryzae 54.02 0.00e+00 831.00
IUUC-Mpo-057538 Magnaporthe poae 53.59 0.00e+00 870.00
IUUC-Mtr-058310 Medicago truncatula 46.72 0.00e+00 804.00
IUUC-Mla-058937 Melampsora laricipopulina 49.87 0.00e+00 846.00
IUUC-Mga-059875 Meleagris gallopavo 47.29 0.00e+00 828.00
IUUC-Mvi-060240 Microbotryum violaceum 49.24 0.00e+00 864.00
IUUC-Mmr-061261 Microcebus murinus 47.66 0.00e+00 838.00
IUUC-Mdo-062076 Monodelphis domestica 47.53 0.00e+00 838.00
IUUC-Mmu-063324 Mus musculus 47.53 0.00e+00 836.00
IUUC-Mac-064636 Musa acuminata 45.32 0.00e+00 775.00
IUUC-Mpu-065961 Mustela putorius furo 47.66 0.00e+00 838.00
IUUC-Mlu-067059 Myotis lucifugus 47.28 0.00e+00 808.00
IUUC-Nfi-068277 Neosartorya fischeri 53.29 0.00e+00 880.00
IUUC-Ncr-068659 Neurospora crassa 53.08 0.00e+00 885.00
IUUC-Nle-069034 Nomascus leucogenys 47.66 0.00e+00 838.00
IUUC-Opr-070334 Ochotona princeps 48.02 0.00e+00 786.00
IUUC-Ont-071563 Oreochromis niloticus 46.27 0.00e+00 819.00
IUUC-Oan-073416 Ornithorhynchus anatinus 46.99 0.00e+00 793.00
IUUC-Ocu-074522 Oryctolagus cuniculus 47.66 0.00e+00 835.00
IUUC-Oba-075760 Oryza barthii 44.81 0.00e+00 762.00
IUUC-Obr-076163 Oryza brachyantha 47.09 0.00e+00 788.00
IUUC-Ogl-077450 Oryza glaberrima 45.57 0.00e+00 786.00
IUUC-Ogu-078994 Oryza glumaepatula 44.81 0.00e+00 762.00
IUUC-Oin-079856 Oryza indica 47.07 0.00e+00 777.00
IUUC-Olo-080731 Oryza longistaminata 45.35 0.00e+00 751.00
IUUC-Ome-081762 Oryza meridionalis 42.84 0.00e+00 701.00
IUUC-Oni-082324 Oryza nivara 44.81 0.00e+00 761.00
IUUC-Opu-083400 Oryza punctata 45.40 0.00e+00 764.00
IUUC-Oru-084829 Oryza rufipogon 44.81 0.00e+00 761.00
IUUC-Osa-086026 Oryza sativa 45.82 0.00e+00 791.00
IUUC-Ola-087245 Oryzias latipes 46.52 0.00e+00 823.00
IUUC-Olu-087655 Ostreococcus lucimarinus 45.80 0.00e+00 778.00
IUUC-Oga-088163 Otolemur garnettii 46.66 0.00e+00 799.00
IUUC-Oar-089842 Ovis aries 47.53 0.00e+00 836.00
IUUC-Ptr-090501 Pan troglodytes 47.66 0.00e+00 837.00
IUUC-Pan-092011 Papio anubis 47.66 0.00e+00 838.00
IUUC-Psi-093308 Pelodiscus sinensis 47.41 0.00e+00 834.00
IUUC-Pma-094695 Petromyzon marinus 45.15 0.00e+00 764.00
IUUC-Pno-094785 Phaeosphaeria nodorum 53.79 1.00e-98 352.00
IUUC-Ppa-095638 Physcomitrella patens 46.84 0.00e+00 786.00
IUUC-Pfo-096587 Poecilia formosa 46.27 0.00e+00 823.00
IUUC-Pab-097926 Pongo abelii 46.48 0.00e+00 774.00
IUUC-Pop-099634 Populus trichocarpa 46.28 0.00e+00 791.00
IUUC-Pca-100965 Procavia capensis 46.90 0.00e+00 804.00
IUUC-Ppe-101470 Prunus persica 47.92 0.00e+00 806.00
IUUC-Pva-102451 Pteropus vampyrus 45.03 0.00e+00 667.00
IUUC-Pgr-103453 Puccinia graminis 50.13 0.00e+00 853.00
IUUC-Ptt-103868 Puccinia triticina 50.25 0.00e+00 855.00
IUUC-Pte-104274 Pyrenophora teres 53.03 0.00e+00 893.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 52.77 0.00e+00 846.00
IUUC-Rno-105979 Rattus norvegicus 41.10 0.00e+00 629.00
IUUC-Sce-106269 Saccharomyces cerevisiae 46.16 0.00e+00 766.00
IUUC-Sha-106905 Sarcophilus harrisii 47.53 0.00e+00 837.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 67.93 0.00e+00 1163.00
IUUC-Smo-108828 Selaginella moellendorffii 46.09 0.00e+00 778.00
IUUC-Sit-110239 Setaria italica 46.08 0.00e+00 795.00
IUUC-Sly-111775 Solanum lycopersicum 46.91 0.00e+00 792.00
IUUC-Stu-112906 Solanum tuberosum 45.11 0.00e+00 699.00
IUUC-Sar-113472 Sorex araneus 44.10 6.00e-174 602.00
IUUC-Sbi-113886 Sorghum bicolor 47.16 0.00e+00 788.00
IUUC-Sre-115040 Sporisorium reilianum 49.69 0.00e+00 840.00
IUUC-Ssc-115593 Sus scrofa 47.66 0.00e+00 837.00
IUUC-Tgu-117239 Taeniopygia guttata 47.28 0.00e+00 833.00
IUUC-Tru-118025 Takifugu rubripes 46.09 0.00e+00 816.00
IUUC-Tsy-118824 Tarsius syrichta 44.09 8.00e-178 614.00
IUUC-Tni-120142 Tetraodon nigroviridis 46.02 0.00e+00 812.00
IUUC-Tca-121613 Theobroma cacao 46.84 0.00e+00 802.00
IUUC-Tre-122072 Trichoderma reesei 53.85 0.00e+00 865.00
IUUC-Tvi-122546 Trichoderma virens 53.47 0.00e+00 870.00
IUUC-Tae-125292 Triticum aestivum 45.95 0.00e+00 795.00
IUUC-Tur-126283 Triticum urartu 39.39 0.00e+00 657.00
IUUC-Tme-127041 Tuber melanosporum 54.28 0.00e+00 913.00
IUUC-Tbe-127770 Tupaia belangeri 46.69 0.00e+00 695.00
IUUC-Ttr-129294 Tursiops truncatus 47.66 0.00e+00 836.00
IUUC-Uma-129351 Ustilago maydis 48.50 0.00e+00 831.00
IUUC-Vda-129716 Verticillium dahliae 53.47 0.00e+00 903.00
IUUC-Vpa-130037 Vicugna pacos 39.30 6.00e-91 327.00
IUUC-Vvi-131689 Vitis vinifera 46.84 0.00e+00 792.00
IUUC-Xtr-132633 Xenopus tropicalis 47.41 0.00e+00 834.00
IUUC-Xma-133347 Xiphophorus maculatus 46.40 0.00e+00 824.00
IUUC-Yli-134455 Yarrowia lipolytica 48.37 0.00e+00 797.00
IUUC-Zma-135867 Zea mays 46.84 0.00e+00 801.00
Created Date 25-Jun-2017

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