iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134455

Ensembl Protein ID

CAG82427

UniProt Accession

Q6CB55; Q6CB55_YARLI

Genbank Protein ID

CAG82427.2

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

CR382129

Gene Name

YALI0_C21802g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_C21802g	CAG82427	CAG82427

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-27	92.8	191	225
UBD/Beta-Prp	1.40e-64	216.6	8	305

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf...sd.tllvsGsdDgtikvWDlrtgvll 36
           v+ +++    d ++l+++sdD+t+kvWD+ t  ++
   Q: 191  VNFVEYypgADkPYLITSSDDKTVKVWDYQTKACV 225
           4555557775679***************9987776 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsps 105
            +++++++++ ++f+p +++l+t+ ++g  ++w+++t+++++s++  + + +a +f+ ++++++ gs+D +++v++++tg     +++h d+++ ++++p+
   Q: 8    HSQTRSDRVKGIDFHPTEPWLLTTLYSGVAQIWNYETQTVVKSIEVADVPLRAGRFIARKNWIIVGSDDFIVRVFNYNTGAKEAQFEAHPDYIRVITVHPT 108
           5788999********************************************************************************************** PP
   S: 106  gdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl....ktgkllrtltgghtdsvyslsfdsng..kelvsgs 199
             +++++++d  ir+w+++t++ +e    gh++ +++v+++p++ n ++s++lDrtv++W+l       +   tl+   t  v+ +++ +    ++l++ s
   Q: 109  LPYVLTAGDDMSIRLWNWDTNWTMERQYLGHSHYIMYVAFNPKDtNTFASACLDRTVKVWSLsgasTVSRPNFTLEAHATAGVNFVEYYPGAdkPYLITSS 209
           *************************999**********************************5444444444556888899******8886677******* PP
   S: 200  ldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkkn 297
           +d+tvk+wd+qt+ cv t++ght+nv+   f+p+   ++sg++D+++++W+  + +l +tl+++ ++ ++v v    +++lv++++d  + ++ l k+
   Q: 210  DDKTVKVWDYQTKACVATMEGHTNNVSFAVFHPDLPVIISGAEDNTVKVWNANTYQLEQTLNYSYERAWCVGV--KRGSNLVAVGFDAGAVVLRLGKE 305
           *************************************************************************..8899*********9999988765 PP

Organism

Yarrowia lipolytica

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MKLEIKRHSQ TRSDRVKGID FHPTEPWLLT TLYSGVAQIW NYETQTVVKS IEVADVPLRA 60
GRFIARKNWI IVGSDDFIVR VFNYNTGAKE AQFEAHPDYI RVITVHPTLP YVLTAGDDMS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGCTCG AAATCAAGGT GAGTAATTGA GCGATTCACG CGGCCATGAC GACGACTAAC 60
ACAGCGACAC TCGCAGACTC GTTCTGACCG AGTCAAGGGA ATCGATTTCC ACCCCACTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0005829--C:cytosol
GO:0000139--C:Golgi membrane
GO:0005634--C:nucleus
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0032511--P:late endosome to vacuole transport via multivesicular body sorting pathway
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG

yli:YALI0C21802g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	42.81	0.00e+00	684.00
IUUC-Aml-002154	Ailuropoda melanoleuca	50.31	0.00e+00	870.00
IUUC-Atr-003090	Amborella trichopoda	49.64	0.00e+00	832.00
IUUC-Apl-003976	Anas platyrhynchos	50.68	0.00e+00	873.00
IUUC-Aca-004301	Anolis carolinensis	48.95	0.00e+00	875.00
IUUC-Aly-005643	Arabidopsis lyrata	48.85	0.00e+00	824.00
IUUC-Ath-007630	Arabidopsis thaliana	49.46	0.00e+00	839.00
IUUC-Ago-007914	Ashbya gossypii	52.18	0.00e+00	857.00
IUUC-Acl-008237	Aspergillus clavatus	59.06	0.00e+00	987.00
IUUC-Afl-008535	Aspergillus flavus	55.16	0.00e+00	943.00
IUUC-Afu-008845	Aspergillus fumigatus	59.31	0.00e+00	967.00
IUUC-Ani-009135	Aspergillus nidulans	59.27	0.00e+00	947.00
IUUC-Ang-009654	Aspergillus niger	60.48	0.00e+00	873.00
IUUC-Aor-009939	Aspergillus oryzae	55.78	0.00e+00	1005.00
IUUC-Ate-010355	Aspergillus terreus	57.19	0.00e+00	953.00
IUUC-Ame-010922	Astyanax mexicanus	46.55	0.00e+00	758.00
IUUC-Bgr-012249	Blumeria graminis	58.25	0.00e+00	958.00
IUUC-Bta-013579	Bos taurus	50.97	0.00e+00	794.00
IUUC-Bci-013866	Botrytis cinerea	58.64	0.00e+00	934.00
IUUC-Bdi-015046	Brachypodium distachyon	49.75	0.00e+00	823.00
IUUC-Bol-016338	Brassica oleracea	50.00	0.00e+00	834.00
IUUC-Bra-017576	Brassica rapa	50.00	0.00e+00	832.00
IUUC-Cel-018387	Caenorhabditis elegans	47.72	0.00e+00	813.00
IUUC-Cja-019145	Callithrix jacchus	50.43	0.00e+00	871.00
IUUC-Cfa-020564	Canis familiaris	50.31	0.00e+00	870.00
IUUC-Cpo-022201	Cavia porcellus	50.43	0.00e+00	872.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	49.82	0.00e+00	769.00
IUUC-Csa-023383	Chlorocebus sabaeus	53.48	0.00e+00	681.00
IUUC-Cho-024454	Choloepus hoffmanni	47.97	0.00e+00	749.00
IUUC-Cin-025681	Ciona intestinalis	50.86	0.00e+00	830.00
IUUC-Csv-026012	Ciona savignyi	50.95	0.00e+00	818.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	54.57	0.00e+00	848.00
IUUC-Cne-026986	Cryptococcus neoformans	51.14	0.00e+00	859.00
IUUC-Cme-027219	Cyanidioschyzon merolae	44.27	0.00e+00	738.00
IUUC-Dre-027846	Danio rerio	50.56	0.00e+00	873.00
IUUC-Dor-030462	Dipodomys ordii	49.70	0.00e+00	706.00
IUUC-Dse-031268	Dothistroma septosporum	55.67	0.00e+00	943.00
IUUC-Dme-031791	Drosophila melanogaster	47.60	0.00e+00	801.00
IUUC-Ete-033166	Echinops telfairi	48.58	2.00e-165	574.00
IUUC-Eca-034180	Equus caballus	49.14	0.00e+00	830.00
IUUC-Eeu-035086	Erinaceus europaeus	42.63	2.00e-93	335.00
IUUC-Fca-036265	Felis catus	50.31	0.00e+00	868.00
IUUC-Fal-037202	Ficedula albicollis	50.26	0.00e+00	835.00
IUUC-Fox-037711	Fusarium oxysporum	58.77	0.00e+00	887.00
IUUC-Fso-038268	Fusarium solani	58.85	0.00e+00	892.00
IUUC-Gmo-039046	Gadus morhua	50.68	0.00e+00	872.00
IUUC-Ggr-039863	Gaeumannomyces graminis	58.77	0.00e+00	913.00
IUUC-Gga-041112	Gallus gallus	50.80	0.00e+00	876.00
IUUC-Gac-041733	Gasterosteus aculeatus	50.56	0.00e+00	846.00
IUUC-Gma-042910	Glycine max	50.86	0.00e+00	843.00
IUUC-Ggo-044984	Gorilla gorilla	50.43	0.00e+00	868.00
IUUC-Hsa-046698	Homo sapiens	50.43	0.00e+00	868.00
IUUC-Hvu-047669	Hordeum vulgare	53.91	5.00e-126	441.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	50.31	0.00e+00	868.00
IUUC-Kpa-049265	Komagataella pastoris	58.20	0.00e+00	983.00
IUUC-Lch-050473	Latimeria chalumnae	50.80	0.00e+00	874.00
IUUC-Lpe-051579	Leersia perrieri	50.12	0.00e+00	819.00
IUUC-Loc-052675	Lepisosteus oculatus	50.56	0.00e+00	874.00
IUUC-Lma-053218	Leptosphaeria maculans	55.23	0.00e+00	905.00
IUUC-Laf-053757	Loxodonta africana	50.31	0.00e+00	865.00
IUUC-Mcc-054859	Macaca mulatta	50.43	0.00e+00	870.00
IUUC-Meu-056174	Macropus eugenii	44.35	2.00e-79	288.00
IUUC-Mor-057264	Magnaporthe oryzae	59.06	0.00e+00	907.00
IUUC-Mpo-057538	Magnaporthe poae	58.40	0.00e+00	927.00
IUUC-Mtr-058310	Medicago truncatula	49.59	0.00e+00	850.00
IUUC-Mla-058937	Melampsora laricipopulina	50.73	0.00e+00	854.00
IUUC-Mga-059875	Meleagris gallopavo	50.55	0.00e+00	870.00
IUUC-Mvi-060240	Microbotryum violaceum	51.91	0.00e+00	874.00
IUUC-Mmr-061261	Microcebus murinus	50.31	0.00e+00	869.00
IUUC-Mdo-062076	Monodelphis domestica	50.56	0.00e+00	875.00
IUUC-Mmu-063324	Mus musculus	50.43	0.00e+00	871.00
IUUC-Mac-064636	Musa acuminata	50.06	0.00e+00	825.00
IUUC-Mpu-065961	Mustela putorius furo	50.31	0.00e+00	868.00
IUUC-Mlu-067059	Myotis lucifugus	49.57	0.00e+00	851.00
IUUC-Nfi-068277	Neosartorya fischeri	59.55	0.00e+00	961.00
IUUC-Ncr-068659	Neurospora crassa	56.78	0.00e+00	964.00
IUUC-Nle-069034	Nomascus leucogenys	50.43	0.00e+00	870.00
IUUC-Opr-070334	Ochotona princeps	52.03	0.00e+00	823.00
IUUC-Ont-071563	Oreochromis niloticus	50.43	0.00e+00	869.00
IUUC-Oan-073416	Ornithorhynchus anatinus	50.26	0.00e+00	833.00
IUUC-Ocu-074522	Oryctolagus cuniculus	50.31	0.00e+00	867.00
IUUC-Oba-075760	Oryza barthii	49.14	0.00e+00	813.00
IUUC-Obr-076163	Oryza brachyantha	49.39	0.00e+00	823.00
IUUC-Ogl-077450	Oryza glaberrima	49.88	0.00e+00	838.00
IUUC-Ogu-078994	Oryza glumaepatula	49.14	0.00e+00	812.00
IUUC-Oin-079856	Oryza indica	48.24	0.00e+00	808.00
IUUC-Olo-080731	Oryza longistaminata	49.55	0.00e+00	800.00
IUUC-Ome-081554	Oryza meridionalis	46.79	0.00e+00	743.00
IUUC-Oni-082324	Oryza nivara	49.14	0.00e+00	812.00
IUUC-Opu-083400	Oryza punctata	48.26	0.00e+00	789.00
IUUC-Oru-084829	Oryza rufipogon	49.14	0.00e+00	812.00
IUUC-Osa-086026	Oryza sativa	50.00	0.00e+00	840.00
IUUC-Ola-087245	Oryzias latipes	50.68	0.00e+00	872.00
IUUC-Olu-087655	Ostreococcus lucimarinus	47.90	0.00e+00	787.00
IUUC-Oga-088163	Otolemur garnettii	48.83	0.00e+00	836.00
IUUC-Oar-089842	Ovis aries	50.43	0.00e+00	870.00
IUUC-Ptr-090501	Pan troglodytes	50.43	0.00e+00	869.00
IUUC-Pan-092011	Papio anubis	50.43	0.00e+00	870.00
IUUC-Psi-093308	Pelodiscus sinensis	50.68	0.00e+00	873.00
IUUC-Pma-094695	Petromyzon marinus	49.17	0.00e+00	792.00
IUUC-Pno-094785	Phaeosphaeria nodorum	62.59	1.00e-110	391.00
IUUC-Ppa-095412	Physcomitrella patens	50.72	0.00e+00	863.00
IUUC-Pfo-096587	Poecilia formosa	50.93	0.00e+00	875.00
IUUC-Pab-097926	Pongo abelii	49.02	0.00e+00	797.00
IUUC-Pop-099634	Populus trichocarpa	50.12	0.00e+00	832.00
IUUC-Pca-100965	Procavia capensis	49.20	0.00e+00	834.00
IUUC-Ppe-101470	Prunus persica	50.36	0.00e+00	845.00
IUUC-Pva-102451	Pteropus vampyrus	49.70	0.00e+00	705.00
IUUC-Pgr-103453	Puccinia graminis	51.11	0.00e+00	865.00
IUUC-Ptt-103868	Puccinia triticina	49.65	0.00e+00	863.00
IUUC-Pte-104274	Pyrenophora teres	56.88	0.00e+00	935.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	54.89	0.00e+00	889.00
IUUC-Rno-105979	Rattus norvegicus	44.84	0.00e+00	672.00
IUUC-Sce-106269	Saccharomyces cerevisiae	51.05	0.00e+00	881.00
IUUC-Sha-106905	Sarcophilus harrisii	50.56	0.00e+00	875.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	49.06	0.00e+00	797.00
IUUC-Spo-108299	Schizosaccharomyces pombe	48.81	0.00e+00	815.00
IUUC-Smo-108695	Selaginella moellendorffii	51.17	0.00e+00	843.00
IUUC-Sit-110239	Setaria italica	49.75	0.00e+00	832.00
IUUC-Sly-111775	Solanum lycopersicum	50.49	0.00e+00	840.00
IUUC-Stu-112906	Solanum tuberosum	49.02	0.00e+00	742.00
IUUC-Sar-113472	Sorex araneus	48.96	0.00e+00	641.00
IUUC-Sbi-114052	Sorghum bicolor	50.74	0.00e+00	841.00
IUUC-Sre-115040	Sporisorium reilianum	50.88	0.00e+00	857.00
IUUC-Ssc-115593	Sus scrofa	50.31	0.00e+00	869.00
IUUC-Tgu-117239	Taeniopygia guttata	50.68	0.00e+00	876.00
IUUC-Tru-118025	Takifugu rubripes	50.49	0.00e+00	865.00
IUUC-Tsy-118824	Tarsius syrichta	47.87	0.00e+00	638.00
IUUC-Tni-120142	Tetraodon nigroviridis	50.80	0.00e+00	868.00
IUUC-Tca-121613	Theobroma cacao	48.78	0.00e+00	838.00
IUUC-Tre-122072	Trichoderma reesei	58.22	0.00e+00	947.00
IUUC-Tvi-122546	Trichoderma virens	57.60	0.00e+00	938.00
IUUC-Tae-125385	Triticum aestivum	49.38	0.00e+00	819.00
IUUC-Tur-126283	Triticum urartu	43.06	0.00e+00	683.00
IUUC-Tme-127041	Tuber melanosporum	58.40	0.00e+00	979.00
IUUC-Tbe-127770	Tupaia belangeri	50.15	0.00e+00	718.00
IUUC-Ttr-129294	Tursiops truncatus	50.31	0.00e+00	866.00
IUUC-Uma-129351	Ustilago maydis	51.41	0.00e+00	862.00
IUUC-Vda-129716	Verticillium dahliae	58.40	0.00e+00	964.00
IUUC-Vvi-131689	Vitis vinifera	49.42	0.00e+00	845.00
IUUC-Xtr-132633	Xenopus tropicalis	50.06	0.00e+00	868.00
IUUC-Xma-133347	Xiphophorus maculatus	51.17	0.00e+00	876.00
IUUC-Zma-135706	Zea mays	50.12	0.00e+00	828.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence