iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-002493

Ensembl Protein ID

ERM96351

UniProt Accession

W1NLI2; W1NLI2_AMBTC

Genbank Protein ID

ERM96351.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KI397142

Gene Name

AMTR_s00001p00220200

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00001p00220200	ERM96351	ERM96351

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.80e-40	134.2	50	86
UBD/Beta-Prp	9.70e-77	258.5	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++ +++l
   Q: 50   HDGPVRGVHFhKTqPLFVSGGDDYKIKVWNYKMHRCL 86
           99*********4459***************9999887 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           t +++++++++ + f+ ++++++++  +g i++wd+++g+l+ ++ +h+++v+ v f+++++++v+g++D+ ikvw+++   c+ tl gh d++++++f+ 
   Q: 3    TKFETKSNRVKGLSFHSKRPWILASLHSGVIQLWDYRMGTLIDRFDEHDGPVRGVHFHKTQPLFVSGGDDYKIKVWNYKMHRCLFTLLGHLDYIRTVQFHN 103
           67889999********************************************************************************************* PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl..........................ktgkllrtl.... 175
           +  ++vs+s+d+tir+w++++++c++ +l+gh++ v+c+++hp+++l+vs+slD+tvr+Wd+                                       
   Q: 104  EYPWIVSASDDQTIRIWNWQSRTCIS-VLTGHNHYVMCASFHPKEDLVVSASLDQTVRVWDIgalrkktvspaddilrltqmntelfgG-------Vdavv 196
           **************************.**************************************************666666666662.......04444 PP
   S: 176  ....tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisv 270
               +g h++ v++ +f+++ + +vsg++d++vklw +  ++   v+tl+ght+nv++v f+ +++++vs s+D+sir+Wd+++++ ++t+ +++++++  
   Q: 197  kyvlEG-HDRGVNWAAFHPSLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHTNNVSCVMFHARQDIIVSNSEDKSIRVWDVTKRTGVQTFRREHDRFWIL 296
           444265.********************************777668******************************************************** PP
   S: 271  avlsfgdnvlvlgsedskvniwklkknep 299
           a+ +++ n l++g  ds   ++kl++++p
   Q: 297  AA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           **.6666655555.689999999988765 PP

Organism

Amborella trichopoda

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLSFHSK RPWILASLHS GVIQLWDYRM GTLIDRFDEH DGPVRGVHFH 60
KTQPLFVSGG DDYKIKVWNY KMHRCLFTLL GHLDYIRTVQ FHNEYPWIVS ASDDQTIRIW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCTGACGA AATTCGAAAC AAAGAGTAAT AGGGTTAAGG GTCTGAGCTT TCACAGTAAG 60
CGGCCATGGA TTCTGGCTAG TCTTCACAGT GGCGTGATTC AGCTATGGGA TTATCGCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

atr:18424283

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	79.08	0.00e+00	1979.00
IUUC-Aml-001758	Ailuropoda melanoleuca	54.98	0.00e+00	1348.00
IUUC-Apl-003385	Anas platyrhynchos	50.51	0.00e+00	1039.00
IUUC-Aca-005154	Anolis carolinensis	78.92	2.00e-95	340.00
IUUC-Aly-006020	Arabidopsis lyrata	79.31	0.00e+00	1965.00
IUUC-Ath-007058	Arabidopsis thaliana	80.51	0.00e+00	1980.00
IUUC-Ago-007992	Ashbya gossypii	42.86	0.00e+00	951.00
IUUC-Acl-008027	Aspergillus clavatus	55.49	0.00e+00	970.00
IUUC-Afl-008644	Aspergillus flavus	55.35	0.00e+00	970.00
IUUC-Afu-008964	Aspergillus fumigatus	47.93	0.00e+00	1113.00
IUUC-Ani-009379	Aspergillus nidulans	55.83	0.00e+00	985.00
IUUC-Ang-009756	Aspergillus niger	55.56	0.00e+00	976.00
IUUC-Aor-010174	Aspergillus oryzae	55.35	0.00e+00	971.00
IUUC-Ate-010302	Aspergillus terreus	47.72	0.00e+00	1139.00
IUUC-Ame-011229	Astyanax mexicanus	54.98	0.00e+00	1332.00
IUUC-Bgr-012300	Blumeria graminis	46.89	0.00e+00	1058.00
IUUC-Bta-012524	Bos taurus	55.46	0.00e+00	1342.00
IUUC-Bci-013781	Botrytis cinerea	47.64	0.00e+00	1115.00
IUUC-Bdi-014549	Brachypodium distachyon	79.66	0.00e+00	2033.00
IUUC-Bol-015925	Brassica oleracea	77.89	0.00e+00	1917.00
IUUC-Bra-016978	Brassica rapa	79.10	0.00e+00	1952.00
IUUC-Cel-018115	Caenorhabditis elegans	55.33	0.00e+00	945.00
IUUC-Cja-019107	Callithrix jacchus	54.38	0.00e+00	1325.00
IUUC-Cfa-020675	Canis familiaris	54.65	0.00e+00	1320.00
IUUC-Cpo-021813	Cavia porcellus	55.54	0.00e+00	1357.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	72.48	0.00e+00	1286.00
IUUC-Csa-023523	Chlorocebus sabaeus	55.78	0.00e+00	1362.00
IUUC-Cho-024704	Choloepus hoffmanni	41.90	4.00e-169	587.00
IUUC-Cin-025572	Ciona intestinalis	52.05	0.00e+00	1255.00
IUUC-Csv-025864	Ciona savignyi	59.64	0.00e+00	1013.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	55.72	0.00e+00	977.00
IUUC-Cne-027053	Cryptococcus neoformans	50.93	0.00e+00	1177.00
IUUC-Cme-027222	Cyanidioschyzon merolae	41.99	4.00e-146	511.00
IUUC-Dre-027421	Danio rerio	55.58	0.00e+00	1342.00
IUUC-Dno-029303	Dasypus novemcinctus	55.50	0.00e+00	1364.00
IUUC-Dor-030290	Dipodomys ordii	54.13	3.00e-166	578.00
IUUC-Dse-031543	Dothistroma septosporum	45.29	0.00e+00	1034.00
IUUC-Dme-031945	Drosophila melanogaster	62.09	0.00e+00	1045.00
IUUC-Ete-032873	Echinops telfairi	61.67	0.00e+00	1061.00
IUUC-Eca-033773	Equus caballus	54.58	0.00e+00	1319.00
IUUC-Fca-035739	Felis catus	54.47	0.00e+00	1319.00
IUUC-Fal-037263	Ficedula albicollis	51.83	0.00e+00	1200.00
IUUC-Fox-037738	Fusarium oxysporum	46.74	0.00e+00	1108.00
IUUC-Fso-038153	Fusarium solani	47.27	0.00e+00	1101.00
IUUC-Gmo-039602	Gadus morhua	52.54	0.00e+00	1232.00
IUUC-Ggr-039931	Gaeumannomyces graminis	55.10	0.00e+00	962.00
IUUC-Gga-040590	Gallus gallus	55.42	0.00e+00	1363.00
IUUC-Gac-041318	Gasterosteus aculeatus	55.82	0.00e+00	1354.00
IUUC-Gma-043257	Glycine max	80.77	0.00e+00	2008.00
IUUC-Ggo-045029	Gorilla gorilla	55.30	0.00e+00	1352.00
IUUC-Hsa-046078	Homo sapiens	55.30	0.00e+00	1353.00
IUUC-Hvu-047556	Hordeum vulgare	79.46	0.00e+00	2037.00
IUUC-Kpa-049256	Komagataella pastoris	53.12	0.00e+00	901.00
IUUC-Lch-049706	Latimeria chalumnae	55.19	0.00e+00	1352.00
IUUC-Lpe-051316	Leersia perrieri	80.07	0.00e+00	1996.00
IUUC-Loc-051867	Lepisosteus oculatus	50.93	0.00e+00	831.00
IUUC-Lma-053138	Leptosphaeria maculans	55.60	0.00e+00	978.00
IUUC-Laf-053510	Loxodonta africana	56.16	0.00e+00	1380.00
IUUC-Mcc-055836	Macaca mulatta	55.39	0.00e+00	1352.00
IUUC-Meu-056238	Macropus eugenii	57.90	0.00e+00	785.00
IUUC-Mor-057172	Magnaporthe oryzae	46.70	0.00e+00	1092.00
IUUC-Mpo-057300	Magnaporthe poae	47.47	0.00e+00	1085.00
IUUC-Mtr-058248	Medicago truncatula	79.80	0.00e+00	2008.00
IUUC-Mla-059019	Melampsora laricipopulina	50.00	0.00e+00	1225.00
IUUC-Mga-059499	Meleagris gallopavo	55.33	0.00e+00	1359.00
IUUC-Mvi-060336	Microbotryum violaceum	59.45	0.00e+00	1066.00
IUUC-Mmr-061102	Microcebus murinus	54.90	0.00e+00	1335.00
IUUC-Mdo-062594	Monodelphis domestica	55.99	0.00e+00	1380.00
IUUC-Mmu-063736	Mus musculus	55.06	0.00e+00	1347.00
IUUC-Mac-065398	Musa acuminata	75.33	0.00e+00	1884.00
IUUC-Mpu-066701	Mustela putorius furo	55.35	0.00e+00	1361.00
IUUC-Mlu-067392	Myotis lucifugus	55.58	0.00e+00	1351.00
IUUC-Nfi-068270	Neosartorya fischeri	55.73	0.00e+00	974.00
IUUC-Ncr-068892	Neurospora crassa	55.84	0.00e+00	974.00
IUUC-Nle-069634	Nomascus leucogenys	67.56	0.00e+00	955.00
IUUC-Ont-072488	Oreochromis niloticus	55.26	0.00e+00	1342.00
IUUC-Ocu-074211	Oryctolagus cuniculus	55.46	0.00e+00	1353.00
IUUC-Oba-075761	Oryza barthii	85.97	0.00e+00	1536.00
IUUC-Obr-076429	Oryza brachyantha	79.75	0.00e+00	1996.00
IUUC-Ogl-077364	Oryza glaberrima	85.97	0.00e+00	1536.00
IUUC-Ogu-078257	Oryza glumaepatula	85.85	0.00e+00	1535.00
IUUC-Oin-079274	Oryza indica	85.85	0.00e+00	1535.00
IUUC-Olo-080466	Oryza longistaminata	85.80	0.00e+00	1514.00
IUUC-Ome-081993	Oryza meridionalis	86.64	0.00e+00	1384.00
IUUC-Oni-082874	Oryza nivara	85.97	0.00e+00	1534.00
IUUC-Opu-083885	Oryza punctata	80.64	0.00e+00	2012.00
IUUC-Oru-084274	Oryza rufipogon	85.97	0.00e+00	1536.00
IUUC-Osa-085565	Oryza sativa	85.97	0.00e+00	1536.00
IUUC-Ola-086921	Oryzias latipes	55.14	0.00e+00	1330.00
IUUC-Olu-087639	Ostreococcus lucimarinus	62.51	0.00e+00	1573.00
IUUC-Oga-087991	Otolemur garnettii	52.59	0.00e+00	1263.00
IUUC-Oar-089590	Ovis aries	55.38	0.00e+00	1357.00
IUUC-Ptr-090808	Pan troglodytes	55.38	0.00e+00	1353.00
IUUC-Pan-092475	Papio anubis	55.65	0.00e+00	1356.00
IUUC-Psi-093044	Pelodiscus sinensis	55.01	0.00e+00	896.00
IUUC-Pno-094839	Phaeosphaeria nodorum	54.42	0.00e+00	910.00
IUUC-Ppa-095254	Physcomitrella patens	71.86	0.00e+00	1823.00
IUUC-Pfo-097493	Poecilia formosa	55.83	0.00e+00	1341.00
IUUC-Pab-098497	Pongo abelii	55.70	0.00e+00	1361.00
IUUC-Pop-099992	Populus trichocarpa	84.32	0.00e+00	2038.00
IUUC-Pca-100413	Procavia capensis	61.69	0.00e+00	702.00
IUUC-Ppe-101899	Prunus persica	82.18	0.00e+00	2039.00
IUUC-Pva-102126	Pteropus vampyrus	52.97	0.00e+00	1280.00
IUUC-Pgr-103376	Puccinia graminis	58.87	0.00e+00	1045.00
IUUC-Ptt-103978	Puccinia triticina	52.67	0.00e+00	811.00
IUUC-Pte-104126	Pyrenophora teres	54.90	0.00e+00	936.00
IUUC-Rno-105428	Rattus norvegicus	55.30	0.00e+00	1352.00
IUUC-Sce-106464	Saccharomyces cerevisiae	48.98	0.00e+00	827.00
IUUC-Sha-107301	Sarcophilus harrisii	55.15	0.00e+00	1336.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	45.37	0.00e+00	1054.00
IUUC-Spo-108217	Schizosaccharomyces pombe	44.10	0.00e+00	1030.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	47.00	0.00e+00	1110.00
IUUC-Smo-109582	Selaginella moellendorffii	77.87	0.00e+00	1397.00
IUUC-Sit-109697	Setaria italica	80.90	0.00e+00	2016.00
IUUC-Sly-111759	Solanum lycopersicum	81.53	0.00e+00	2060.00
IUUC-Stu-112564	Solanum tuberosum	81.53	0.00e+00	2055.00
IUUC-Sbi-114388	Sorghum bicolor	85.97	0.00e+00	1537.00
IUUC-Sre-115209	Sporisorium reilianum	54.86	0.00e+00	994.00
IUUC-Ssc-115933	Sus scrofa	55.46	0.00e+00	1356.00
IUUC-Tgu-117109	Taeniopygia guttata	44.57	2.00e-111	395.00
IUUC-Tru-117772	Takifugu rubripes	55.06	0.00e+00	1308.00
IUUC-Tsy-119105	Tarsius syrichta	53.38	0.00e+00	1053.00
IUUC-Tni-120556	Tetraodon nigroviridis	42.63	0.00e+00	882.00
IUUC-Tca-121545	Theobroma cacao	82.85	0.00e+00	2079.00
IUUC-Tre-121951	Trichoderma reesei	58.22	0.00e+00	974.00
IUUC-Tvi-122359	Trichoderma virens	56.18	0.00e+00	979.00
IUUC-Tae-123688	Triticum aestivum	79.62	0.00e+00	2037.00
IUUC-Tur-126754	Triticum urartu	77.44	0.00e+00	1932.00
IUUC-Tme-127170	Tuber melanosporum	47.64	0.00e+00	1138.00
IUUC-Tbe-127882	Tupaia belangeri	69.35	2.00e-128	452.00
IUUC-Ttr-128217	Tursiops truncatus	53.21	0.00e+00	1283.00
IUUC-Uma-129337	Ustilago maydis	55.33	0.00e+00	994.00
IUUC-Vda-129828	Verticillium dahliae	47.00	0.00e+00	1095.00
IUUC-Vpa-130537	Vicugna pacos	54.98	0.00e+00	1334.00
IUUC-Vvi-130958	Vitis vinifera	83.09	0.00e+00	2066.00
IUUC-Xtr-132857	Xenopus tropicalis	53.30	0.00e+00	1262.00
IUUC-Xma-133138	Xiphophorus maculatus	55.83	0.00e+00	1342.00
IUUC-Yli-134399	Yarrowia lipolytica	49.59	0.00e+00	844.00
IUUC-Zma-135612	Zea mays	78.42	0.00e+00	1996.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence