iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097518

Ensembl Protein ID

ENSPFOP00000011480.2

UniProt Accession

A0A087Y0C7; A0A087Y0C7_POEFO

Genbank Protein ID

ENSPFOP00000011480

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01007188

Gene Name

TLE4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000011027.2	ENSPFOT00000011496.2	ENSPFOP00000011480.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-22	78.5	618	656
UBD/Beta-Prp	3.70e-40	138.5	486	655

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 618  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 656
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.t 132
           +h + v av++s+ +   v ++  + +kvwd+s   + ++v+ l   + +++++s+++ p+g +l++G++ +t+ +wdl t +   +  
   Q: 486  SHGEVVCAVTISNPTR-HVYTGGKGCVKVWDIShpgNKTPVSQLDclNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLATPTPRIKaE 573
           4555788899999985.555555579*******999888888888889*********************************99877658 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
           l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 574  LTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQL 655
           888888888999********************************9.********************************99754 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MYPPARHPVE VPHQPGQPFK FTVTESCDRI KEEFQFLQAQ YHSLKLECEK LASEKTEMQR 60
HYVMYYEMSY GLNIEMHKQA EIVKRLNAIC AQVIPFLSQE HQQQVVQAVE RAKQVTMAEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTACCCCC CGGCGCGGCA TCCGGTAAGT GGAGAACAGA AGCAGAAAGT GTCAAAACAG 60
CGCAGATTAA CTGCAGCGCG CCTGATGCGT AATCAGTTTA GATACAGTTT CCGTGCCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005279	Anolis carolinensis	87.80	0.00e+00	1177.00
IUUC-Bta-012646	Bos taurus	86.52	0.00e+00	1195.00
IUUC-Cel-018361	Caenorhabditis elegans	58.43	8.00e-121	427.00
IUUC-Cja-019079	Callithrix jacchus	87.29	0.00e+00	1220.00
IUUC-Cfa-020987	Canis familiaris	87.65	0.00e+00	1199.00
IUUC-Cpo-021606	Cavia porcellus	85.88	0.00e+00	1175.00
IUUC-Csa-023445	Chlorocebus sabaeus	87.29	0.00e+00	1199.00
IUUC-Cho-024590	Choloepus hoffmanni	78.36	0.00e+00	1043.00
IUUC-Dor-030533	Dipodomys ordii	82.38	0.00e+00	1021.00
IUUC-Dme-031576	Drosophila melanogaster	86.59	0.00e+00	668.00
IUUC-Ete-032887	Echinops telfairi	75.84	0.00e+00	1070.00
IUUC-Eeu-035237	Erinaceus europaeus	74.58	0.00e+00	1004.00
IUUC-Fca-036030	Felis catus	87.39	0.00e+00	1214.00
IUUC-Fal-037460	Ficedula albicollis	87.65	0.00e+00	1195.00
IUUC-Gga-040416	Gallus gallus	87.55	0.00e+00	1204.00
IUUC-Gac-041739	Gasterosteus aculeatus	80.62	0.00e+00	1093.00
IUUC-Ggo-045633	Gorilla gorilla	84.02	0.00e+00	1187.00
IUUC-Hsa-046461	Homo sapiens	83.85	0.00e+00	1197.00
IUUC-Itr-048974	Ictidomys tridecemlineatus	87.42	0.00e+00	1206.00
IUUC-Lch-049943	Latimeria chalumnae	86.04	0.00e+00	1133.00
IUUC-Loc-052835	Lepisosteus oculatus	88.44	0.00e+00	1178.00
IUUC-Laf-053425	Loxodonta africana	87.52	0.00e+00	1211.00
IUUC-Mcc-055766	Macaca mulatta	83.85	0.00e+00	1197.00
IUUC-Meu-056209	Macropus eugenii	82.57	0.00e+00	1184.00
IUUC-Mmr-061317	Microcebus murinus	84.26	0.00e+00	1198.00
IUUC-Mdo-062956	Monodelphis domestica	87.03	0.00e+00	1202.00
IUUC-Mmu-063576	Mus musculus	87.16	0.00e+00	1192.00
IUUC-Mlu-067456	Myotis lucifugus	84.69	0.00e+00	1140.00
IUUC-Nle-069495	Nomascus leucogenys	87.65	0.00e+00	1192.00
IUUC-Ont-071419	Oreochromis niloticus	95.22	0.00e+00	1246.00
IUUC-Oan-072842	Ornithorhynchus anatinus	84.62	0.00e+00	1177.00
IUUC-Ocu-074453	Oryctolagus cuniculus	86.39	0.00e+00	1184.00
IUUC-Ola-087090	Oryzias latipes	94.06	0.00e+00	1239.00
IUUC-Oga-087939	Otolemur garnettii	87.55	0.00e+00	1207.00
IUUC-Ptr-091048	Pan troglodytes	87.29	0.00e+00	1199.00
IUUC-Pva-103037	Pteropus vampyrus	80.37	0.00e+00	1192.00
IUUC-Sar-113585	Sorex araneus	78.80	0.00e+00	659.00
IUUC-Ssc-116408	Sus scrofa	86.83	0.00e+00	1215.00
IUUC-Tgu-117068	Taeniopygia guttata	87.52	0.00e+00	1198.00
IUUC-Tru-118782	Takifugu rubripes	89.02	0.00e+00	1147.00
IUUC-Tsy-118884	Tarsius syrichta	76.11	0.00e+00	970.00
IUUC-Tni-120404	Tetraodon nigroviridis	87.79	0.00e+00	1191.00
IUUC-Ttr-129285	Tursiops truncatus	82.77	0.00e+00	1198.00
IUUC-Vpa-130577	Vicugna pacos	71.96	8.00e-152	531.00
IUUC-Xtr-132974	Xenopus tropicalis	86.91	0.00e+00	1153.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence