iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004229

UUCD1 version

UUC-AnC-00465

Ensembl Protein ID

ENSACAP00000001164.1

UniProt Accession

G1K983; G1K983_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TAF5L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000001237.2	ENSACAT00000001197.2	ENSACAP00000001164.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-41	137.8	508	540
UBD/Beta-Prp	2.20e-67	227.3	271	560

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gHtd +t+l f +d  l++s+s D++++vWD+r
   Q: 508  GHTDNITSLTFsPDsSLVASASMDNSVRVWDIR 540
           8***********9999***************76 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +spd++lla+g++++++k+w+++++kl                                ++ l gh ++v++++f +d++ l++
   Q: 271  LNTAEISPDSKLLASGFDNSCVKLWSLRSKKLksephlvdvsrihlacdvldeedeeddnvgteMKILRGHCGPVYSTRFLSDSSGLLS 359
           5667889********************************************************************************** PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v++l++sp + +++sGshdrt+r+w  +  + l+ + +gh + v c+++hp++n+l++Gs+D
   Q: 360  CSEDASIRYWDLGSFTNTVLYQGHAYPVWDLDISPCSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCIKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v sl+f++ngk+l+s+++d+++klwdl +g+  ++l+ghtdn++s+ fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSTQQGNTVRLFTG-HRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSSLVASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhnssvisvav 272
           +Wd+r+  ++    ++ s ++ v +
   Q: 536  VWDIRNTYCNAPADGSSSELVGVYT 560
           *****99999988888866666655 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MKRVRTEQIQ VAVSCYLKRR QYVDSEGPLK QGLRLCQTAE EMAANLTVQS ESGCANIISA 60
APCLAEPQQY EVQFGRLCSF LTDSDSQHSH EVMPLLYPLF VYLHLNMVQN GLKSTVDSFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCATGAAAC GTGTACGCAC AGAACAGATT CAGGTGGCAG TTTCCTGCTA CCTCAAACGC 60
AGGCAGTATG TAGATTCGGA AGGTCCTCTG AAGCAAGGGT TGCGCTTATG CCAGACTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0016607--C:nuclear speck
GO:0000932--C:P-body
GO:0030914--C:STAGA complex
GO:0033276--C:transcription factor TFTC complex
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0043966--P:histone H3 acetylation

KEGG

acs:100567115

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	91.34	0.00e+00	1056.00
IUUC-Apl-003636	Anas platyrhynchos	93.40	0.00e+00	1145.00
IUUC-Ame-010599	Astyanax mexicanus	67.22	0.00e+00	830.00
IUUC-Bta-013404	Bos taurus	88.12	0.00e+00	1009.00
IUUC-Cja-019643	Callithrix jacchus	91.68	0.00e+00	1078.00
IUUC-Cfa-020913	Canis familiaris	91.85	0.00e+00	1076.00
IUUC-Cpo-021777	Cavia porcellus	89.64	0.00e+00	1035.00
IUUC-Csa-024184	Chlorocebus sabaeus	91.68	0.00e+00	1079.00
IUUC-Cho-024638	Choloepus hoffmanni	91.85	0.00e+00	1051.00
IUUC-Cin-025618	Ciona intestinalis	34.96	9.00e-91	327.00
IUUC-Csv-025874	Ciona savignyi	34.69	2.00e-90	326.00
IUUC-Cne-026876	Cryptococcus neoformans	46.96	6.00e-69	255.00
IUUC-Dre-028817	Danio rerio	66.94	0.00e+00	811.00
IUUC-Dno-029969	Dasypus novemcinctus	84.38	0.00e+00	1010.00
IUUC-Dor-031117	Dipodomys ordii	89.98	0.00e+00	1065.00
IUUC-Ete-032712	Echinops telfairi	85.06	0.00e+00	958.00
IUUC-Eca-033742	Equus caballus	91.85	0.00e+00	1077.00
IUUC-Eeu-035096	Erinaceus europaeus	89.49	0.00e+00	1081.00
IUUC-Fca-035769	Felis catus	91.03	0.00e+00	1095.00
IUUC-Fal-036645	Ficedula albicollis	93.53	0.00e+00	1082.00
IUUC-Gmo-038636	Gadus morhua	64.33	0.00e+00	786.00
IUUC-Gga-040144	Gallus gallus	93.04	0.00e+00	1115.00
IUUC-Gac-041716	Gasterosteus aculeatus	68.23	0.00e+00	817.00
IUUC-Ggo-044568	Gorilla gorilla	91.85	0.00e+00	1079.00
IUUC-Hsa-046178	Homo sapiens	91.85	0.00e+00	1079.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	85.23	0.00e+00	1041.00
IUUC-Lch-050501	Latimeria chalumnae	79.43	0.00e+00	892.00
IUUC-Loc-052895	Lepisosteus oculatus	79.49	0.00e+00	652.00
IUUC-Laf-053950	Loxodonta africana	88.79	0.00e+00	1034.00
IUUC-Mcc-055450	Macaca mulatta	91.68	0.00e+00	1075.00
IUUC-Meu-056182	Macropus eugenii	88.79	0.00e+00	1029.00
IUUC-Mga-059619	Meleagris gallopavo	93.21	0.00e+00	1118.00
IUUC-Mmr-061074	Microcebus murinus	90.86	0.00e+00	1085.00
IUUC-Mdo-062307	Monodelphis domestica	93.12	0.00e+00	898.00
IUUC-Mmu-063226	Mus musculus	88.29	0.00e+00	1030.00
IUUC-Mpu-066016	Mustela putorius furo	91.51	0.00e+00	1052.00
IUUC-Mlu-067257	Myotis lucifugus	83.31	0.00e+00	1028.00
IUUC-Nle-070139	Nomascus leucogenys	92.02	0.00e+00	1081.00
IUUC-Opr-070243	Ochotona princeps	86.93	0.00e+00	1034.00
IUUC-Ont-072686	Oreochromis niloticus	69.38	0.00e+00	845.00
IUUC-Oan-073670	Ornithorhynchus anatinus	83.90	0.00e+00	858.00
IUUC-Ocu-074525	Oryctolagus cuniculus	90.83	0.00e+00	1072.00
IUUC-Ola-086524	Oryzias latipes	68.72	0.00e+00	868.00
IUUC-Oga-088540	Otolemur garnettii	91.00	0.00e+00	1069.00
IUUC-Oar-089793	Ovis aries	85.06	0.00e+00	947.00
IUUC-Ptr-091154	Pan troglodytes	91.85	0.00e+00	1079.00
IUUC-Pan-092759	Papio anubis	91.68	0.00e+00	1075.00
IUUC-Psi-094008	Pelodiscus sinensis	91.85	0.00e+00	1113.00
IUUC-Pma-094593	Petromyzon marinus	45.90	4.00e-133	468.00
IUUC-Pfo-097409	Poecilia formosa	67.05	0.00e+00	815.00
IUUC-Pab-097946	Pongo abelii	81.66	0.00e+00	935.00
IUUC-Pca-100727	Procavia capensis	86.08	0.00e+00	971.00
IUUC-Pva-103211	Pteropus vampyrus	80.65	0.00e+00	966.00
IUUC-Ptt-103995	Puccinia triticina	46.93	1.00e-68	254.00
IUUC-Rno-105236	Rattus norvegicus	88.96	0.00e+00	1012.00
IUUC-Sha-106833	Sarcophilus harrisii	92.57	0.00e+00	1091.00
IUUC-Sar-113381	Sorex araneus	91.68	0.00e+00	1105.00
IUUC-Ssc-116421	Sus scrofa	89.98	0.00e+00	1091.00
IUUC-Tgu-117143	Taeniopygia guttata	94.40	0.00e+00	1153.00
IUUC-Tru-118680	Takifugu rubripes	68.04	0.00e+00	856.00
IUUC-Tsy-119622	Tarsius syrichta	77.25	0.00e+00	824.00
IUUC-Tni-120131	Tetraodon nigroviridis	66.78	0.00e+00	845.00
IUUC-Ttr-129171	Tursiops truncatus	88.62	0.00e+00	1022.00
IUUC-Xtr-132241	Xenopus tropicalis	81.69	0.00e+00	970.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence