iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004682

Ensembl Protein ID

ENSACAP00000022842.1

UniProt Accession

R4GBZ4; R4GBZ4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

UBE2U

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000029076.1	ENSACAT00000030260.1	ENSACAP00000022842.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.00e-34	117.3	10	145

Active Site

Position(s)	Description	Evidence
90	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyen.GkvClsilkee 89
           l+ke++e e+++  gis++pv + +l+ew ++i+G +d+ +eg   +l+++++e+Y+  PP+v+f t  fhPnv+++ G+ C+++l+++
   Q: 10   LEKEYMEYEESNIFGISITPVGD-NLMEWIAEIEGLKDSLWEGAELQLSLQYNENYNKIPPQVNFNTIPFHPNVDPQsGRPCVDFLDDP 97
           689********************.9****************************************************9*********** PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           +kW+p++++ s+llsiq +l++p  ++++n eaa+++++n ++y+++v
   Q: 98   SKWNPKYTMLSILLSIQVMLSKPVLNNAVNLEAAKMMQNNYRQYRQRV 145
           *********************************************998 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MMHTRAFLLL EKEYMEYEES NIFGISITPV GDNLMEWIAE IEGLKDSLWE GAELQLSLQY 60
NENYNKIPPQ VNFNTIPFHP NVDPQSGRPC VDFLDDPSKW NPKYTMLSIL LSIQVMLSKP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAACAAATT GTATACAGCT TTCTGTTGCT AGGTTACATT TGAGACACTG AGTATTCTAG 60
TCTCCTTGCT TTGCGTTTCC TGTGGATGCT GAGGCTGTAT AGGAAGAAAC AATGGATCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0033503--C:HULC complex
GO:0000790--C:nuclear chromatin
GO:0005524--F:ATP binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0006281--P:DNA repair
GO:0016574--P:histone ubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002211	Ailuropoda melanoleuca	39.17	4.00e-38	150.00
IUUC-Bta-013054	Bos taurus	40.00	1.00e-53	202.00
IUUC-Cja-018784	Callithrix jacchus	39.75	1.00e-49	189.00
IUUC-Cfa-020877	Canis familiaris	45.19	1.00e-54	205.00
IUUC-Cpo-022462	Cavia porcellus	41.05	1.00e-40	158.00
IUUC-Csa-023486	Chlorocebus sabaeus	43.10	3.00e-56	211.00
IUUC-Cho-024685	Choloepus hoffmanni	31.75	3.00e-19	89.00
IUUC-Dno-029061	Dasypus novemcinctus	42.29	3.00e-47	181.00
IUUC-Ete-032233	Echinops telfairi	35.84	2.00e-39	155.00
IUUC-Eca-033400	Equus caballus	53.42	1.00e-34	138.00
IUUC-Fca-035778	Felis catus	45.00	2.00e-55	208.00
IUUC-Ggo-044718	Gorilla gorilla	42.68	1.00e-55	209.00
IUUC-Hsa-046798	Homo sapiens	42.68	2.00e-55	209.00
IUUC-Lch-050337	Latimeria chalumnae	50.00	1.00e-62	233.00
IUUC-Loc-051819	Lepisosteus oculatus	48.02	2.00e-54	206.00
IUUC-Laf-054536	Loxodonta africana	43.75	4.00e-54	203.00
IUUC-Mcc-055028	Macaca mulatta	42.68	1.00e-54	206.00
IUUC-Mmr-061623	Microcebus murinus	42.04	4.00e-44	171.00
IUUC-Mdo-062614	Monodelphis domestica	40.66	3.00e-45	175.00
IUUC-Mmu-063194	Mus musculus	45.58	2.00e-47	182.00
IUUC-Mpu-066467	Mustela putorius furo	42.68	1.00e-48	186.00
IUUC-Mlu-067976	Myotis lucifugus	39.75	7.00e-45	173.00
IUUC-Nle-069407	Nomascus leucogenys	41.00	6.00e-52	197.00
IUUC-Opr-070526	Ochotona princeps	41.14	4.00e-28	117.00
IUUC-Oan-073005	Ornithorhynchus anatinus	51.05	3.00e-58	217.00
IUUC-Ocu-074953	Oryctolagus cuniculus	45.58	2.00e-51	196.00
IUUC-Oga-089061	Otolemur garnettii	43.15	3.00e-56	211.00
IUUC-Oar-090147	Ovis aries	42.52	2.00e-50	192.00
IUUC-Ptr-090873	Pan troglodytes	42.68	6.00e-55	207.00
IUUC-Pan-091873	Papio anubis	42.68	6.00e-55	206.00
IUUC-Psi-093780	Pelodiscus sinensis	55.03	9.00e-43	166.00
IUUC-Pab-098662	Pongo abelii	42.68	3.00e-56	211.00
IUUC-Pca-100167	Procavia capensis	34.08	5.00e-33	134.00
IUUC-Rno-105522	Rattus norvegicus	37.78	2.00e-41	162.00
IUUC-Sar-113070	Sorex araneus	37.33	4.00e-37	147.00
IUUC-Ssc-115890	Sus scrofa	42.04	4.00e-56	211.00
IUUC-Tsy-119341	Tarsius syrichta	40.49	3.00e-41	161.00
IUUC-Tbe-127433	Tupaia belangeri	31.28	5.00e-24	104.00
IUUC-Ttr-128614	Tursiops truncatus	36.55	7.00e-42	164.00
IUUC-Vpa-130777	Vicugna pacos	43.19	1.00e-47	182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence