iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004625

Ensembl Protein ID

ENSACAP00000001260.3

UniProt Accession

G1K9C2; G1K9C2_ANOCA

Protein Name

Uncharacterized protein

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000001364.3	ENSACAT00000001293.3	ENSACAP00000001260.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.70e-20	72.6	434	490

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           +ee letv vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q+  l+ + ++ +  +
   Q: 434  QEEELETVAVLRAQMEVYCSDFHAERAAREKIHEEKEQLAVQLTYLLTEKQQHEGPG 490
           6999*******************************************9988877655 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSSRPLNGLA ENGQHQETEV GNGHPNVPPP VPGAATVEEM VQQMKELITE NNELKEAVRQ 60
HNQAMKDRFE NLSEWSEKLK EEREFYEIKF KEARQCLASK CVENETLKKQ LQTFEEKGED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACATGGGTTC TTTCTCCCAC CCGGGAAATT CCAGATATAT ACACACCCCA CTGGCCTCGT 60
TTCCAATAGA CCTCTCTGAG GATGCCTGCC ATAGATGCAG GTGAAACGTC AGGGGAGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0070530--F:K63-linked polyubiquitin binding
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling

KEGG

acs:100560322

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	51.83	1.00e-132	466.00
IUUC-Apl-003812	Anas platyrhynchos	59.79	6.00e-168	583.00
IUUC-Ame-011116	Astyanax mexicanus	45.39	2.00e-52	199.00
IUUC-Bta-013240	Bos taurus	53.53	3.00e-153	535.00
IUUC-Cja-019911	Callithrix jacchus	54.33	2.00e-142	499.00
IUUC-Cfa-020330	Canis familiaris	54.12	5.00e-141	494.00
IUUC-Cpo-021753	Cavia porcellus	53.55	3.00e-140	491.00
IUUC-Csa-023662	Chlorocebus sabaeus	54.84	2.00e-144	505.00
IUUC-Cho-024574	Choloepus hoffmanni	44.30	4.00e-68	251.00
IUUC-Dre-027720	Danio rerio	41.97	2.00e-96	346.00
IUUC-Dno-029079	Dasypus novemcinctus	52.33	9.00e-124	437.00
IUUC-Dor-030890	Dipodomys ordii	51.56	8.00e-144	503.00
IUUC-Ete-032568	Echinops telfairi	53.73	9.00e-127	446.00
IUUC-Eca-033528	Equus caballus	53.48	1.00e-142	499.00
IUUC-Eeu-035219	Erinaceus europaeus	49.13	3.00e-129	455.00
IUUC-Fca-035852	Felis catus	53.37	2.00e-143	502.00
IUUC-Fal-036862	Ficedula albicollis	61.10	2.00e-166	578.00
IUUC-Gmo-038735	Gadus morhua	38.01	2.00e-73	269.00
IUUC-Gga-040939	Gallus gallus	63.06	1.00e-174	606.00
IUUC-Gac-041580	Gasterosteus aculeatus	42.63	1.00e-91	330.00
IUUC-Ggo-045034	Gorilla gorilla	50.35	2.00e-129	455.00
IUUC-Hsa-046624	Homo sapiens	56.13	5.00e-148	517.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	48.81	5.00e-129	454.00
IUUC-Lch-049720	Latimeria chalumnae	46.04	2.00e-73	269.00
IUUC-Loc-052185	Lepisosteus oculatus	42.36	3.00e-97	348.00
IUUC-Laf-054079	Loxodonta africana	54.56	9.00e-141	493.00
IUUC-Mcc-055674	Macaca mulatta	55.00	2.00e-144	505.00
IUUC-Meu-056769	Macropus eugenii	66.07	2.00e-56	213.00
IUUC-Mga-060203	Meleagris gallopavo	63.01	3.00e-163	567.00
IUUC-Mmr-061492	Microcebus murinus	55.02	1.00e-138	486.00
IUUC-Mdo-063051	Monodelphis domestica	55.31	1.00e-155	543.00
IUUC-Mmu-063409	Mus musculus	52.70	7.00e-149	520.00
IUUC-Mpu-065907	Mustela putorius furo	51.01	3.00e-136	478.00
IUUC-Mlu-066957	Myotis lucifugus	54.59	4.00e-133	468.00
IUUC-Nle-069973	Nomascus leucogenys	55.71	4.00e-146	511.00
IUUC-Opr-071049	Ochotona princeps	51.65	2.00e-126	446.00
IUUC-Ont-071915	Oreochromis niloticus	42.99	1.00e-93	336.00
IUUC-Oan-072965	Ornithorhynchus anatinus	54.40	7.00e-151	526.00
IUUC-Ocu-074029	Oryctolagus cuniculus	52.17	4.00e-122	431.00
IUUC-Ola-087019	Oryzias latipes	40.83	5.00e-86	311.00
IUUC-Oga-088613	Otolemur garnettii	53.82	3.00e-145	508.00
IUUC-Oar-090386	Ovis aries	53.57	5.00e-152	530.00
IUUC-Ptr-091619	Pan troglodytes	55.96	9.00e-147	513.00
IUUC-Pan-092178	Papio anubis	54.91	3.00e-145	508.00
IUUC-Psi-093214	Pelodiscus sinensis	63.46	1.00e-170	592.00
IUUC-Pfo-096901	Poecilia formosa	41.08	9.00e-88	317.00
IUUC-Pab-097560	Pongo abelii	49.38	1.00e-112	400.00
IUUC-Pca-100853	Procavia capensis	47.29	5.00e-64	238.00
IUUC-Pva-102255	Pteropus vampyrus	53.39	4.00e-129	454.00
IUUC-Rno-105812	Rattus norvegicus	51.79	2.00e-142	499.00
IUUC-Sha-107225	Sarcophilus harrisii	61.08	2.00e-108	385.00
IUUC-Sar-113736	Sorex araneus	52.43	3.00e-78	286.00
IUUC-Ssc-115422	Sus scrofa	53.09	2.00e-148	519.00
IUUC-Tgu-116924	Taeniopygia guttata	60.62	2.00e-155	542.00
IUUC-Tru-117695	Takifugu rubripes	40.43	6.00e-85	308.00
IUUC-Tsy-119090	Tarsius syrichta	48.18	1.00e-71	263.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.45	3.00e-85	308.00
IUUC-Tbe-127970	Tupaia belangeri	63.03	7.00e-89	321.00
IUUC-Ttr-129244	Tursiops truncatus	53.06	5.00e-141	494.00
IUUC-Vpa-130313	Vicugna pacos	53.91	5.00e-136	478.00
IUUC-Xtr-132115	Xenopus tropicalis	44.51	2.00e-99	356.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence