iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004935

Ensembl Protein ID

ENSACAP00000002528.2

UniProt Accession

H9G6G4; H9G6G4_ANOCA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000002481.2	ENSACAT00000002593.2	ENSACAP00000002528.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-30	102.7	95	134
UBD/Beta-Prp	7.80e-50	169.7	440	665

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvll 36
           gH+ +v c+af ++ ++lvs +  +D ++ vWD+++g+l+
   Q: 95   GHKHGVACVAFsPSmKYLVSVGypHDMVVNVWDWKKGTLI 134
           8***********777*******************999876 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqcleetlsg 135
           + +++v  ++ spdg+ l++g + +++++ +l+    v++l++h+++vlsl++s+  +g + l+s+s+dr i+v ++e++++le+tl+ 
   Q: 440  DAKSGVHVMSVSPDGQHLASGDRAGNLRIHELRCMGEVMKLEAHDSEVLSLEYSKpeTGmSLLASASRDRLIHVLNVEKNYKLEQTLDD 528
           44556889999999999999999999999999999999999999999999999988777889999999999999999999999999999 PP
   S: 136  hdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl......tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
           h+++++ v++ ++g   ++s+++D+ +  ++ +++  l  l        + +   y +++d ++k+++ + +d+ v+++++ +g+ +  
   Q: 529  HSSAITAVKFTGSGdVKMISCGADKSIY-FRNAQKVSLMGLtfvrthHVAGKTTLYDMDIDITQKYVAVACQDRNVRIYNIASGKLLWG 616
           9999999999999988899999999998.555444444444335333333466677777888889999999999999999999999888 PP
   S: 218  lnght...dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           ++g +      + v+f+p +++l++  sD+si+i d  +g+++ ++ +h
   Q: 617  YKGSQgddGYLLKVQFDPSGTFLATSCSDKSISIIDFHTGECVAKMFGH 665
           8776655577888999999999999999999999999999998766554 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

QVLLEKVLGI TTQTSSGFAC DPNTGQVAYP TGCVVVILNP RKNKQRHIFN TSRKTVSALS 60
FSPDGKYIVT GESGHHPAVR VWEVEDKTQV SELHGHKHGV ACVAFSPSMK YLVSVGYPHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGTGCTGC TTGAAAAAGT GTTGGGCATC ACCACTCAGA CCAGCAGTGG CTTTGCTTGT 60
GACCCAAATA CAGGGCAAGT GGCATATCCA ACAGGGTAAG ACCTTATCTG TAGCTGGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	71.00	0.00e+00	991.00
IUUC-Acl-008257	Aspergillus clavatus	22.39	7.00e-23	102.00
IUUC-Bta-013336	Bos taurus	70.40	0.00e+00	983.00
IUUC-Cja-019094	Callithrix jacchus	71.51	0.00e+00	983.00
IUUC-Cfa-020529	Canis familiaris	70.70	0.00e+00	987.00
IUUC-Cpo-021970	Cavia porcellus	69.55	0.00e+00	957.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	40.66	5.00e-15	76.30
IUUC-Csa-024161	Chlorocebus sabaeus	71.60	0.00e+00	976.00
IUUC-Cho-024310	Choloepus hoffmanni	64.79	1.00e-172	600.00
IUUC-Cin-025412	Ciona intestinalis	56.02	4.00e-53	200.00
IUUC-Csv-026079	Ciona savignyi	40.88	2.00e-74	272.00
IUUC-Dno-029933	Dasypus novemcinctus	66.92	0.00e+00	917.00
IUUC-Dor-031147	Dipodomys ordii	66.87	0.00e+00	915.00
IUUC-Eca-033675	Equus caballus	70.70	0.00e+00	979.00
IUUC-Fca-035826	Felis catus	69.51	0.00e+00	969.00
IUUC-Ggo-045152	Gorilla gorilla	71.45	0.00e+00	975.00
IUUC-Hsa-045891	Homo sapiens	71.60	0.00e+00	977.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	70.25	0.00e+00	989.00
IUUC-Laf-053992	Loxodonta africana	71.15	0.00e+00	988.00
IUUC-Mcc-054994	Macaca mulatta	71.60	0.00e+00	977.00
IUUC-Meu-056815	Macropus eugenii	69.51	0.00e+00	952.00
IUUC-Mtr-058383	Medicago truncatula	29.86	3.00e-41	162.00
IUUC-Mmr-060693	Microcebus murinus	71.45	0.00e+00	994.00
IUUC-Mdo-063007	Monodelphis domestica	72.94	0.00e+00	1019.00
IUUC-Mmu-064067	Mus musculus	71.19	0.00e+00	984.00
IUUC-Mpu-066532	Mustela putorius furo	70.85	0.00e+00	986.00
IUUC-Mlu-066982	Myotis lucifugus	68.41	0.00e+00	959.00
IUUC-Nle-070042	Nomascus leucogenys	70.85	0.00e+00	965.00
IUUC-Opr-070397	Ochotona princeps	71.30	0.00e+00	982.00
IUUC-Ocu-074274	Oryctolagus cuniculus	70.10	0.00e+00	978.00
IUUC-Oga-088577	Otolemur garnettii	69.51	0.00e+00	966.00
IUUC-Oar-090117	Ovis aries	65.17	0.00e+00	912.00
IUUC-Ptr-090553	Pan troglodytes	71.45	0.00e+00	973.00
IUUC-Psi-093710	Pelodiscus sinensis	79.40	0.00e+00	1112.00
IUUC-Pab-098510	Pongo abelii	71.45	0.00e+00	975.00
IUUC-Pva-102895	Pteropus vampyrus	70.85	0.00e+00	986.00
IUUC-Rno-105598	Rattus norvegicus	71.00	0.00e+00	983.00
IUUC-Sha-107013	Sarcophilus harrisii	72.35	0.00e+00	1010.00
IUUC-Sar-113261	Sorex araneus	69.96	0.00e+00	967.00
IUUC-Ssc-115317	Sus scrofa	70.55	0.00e+00	985.00
IUUC-Tsy-118799	Tarsius syrichta	63.25	1.00e-174	607.00
IUUC-Tme-127128	Tuber melanosporum	25.30	2.00e-31	131.00
IUUC-Ttr-128722	Tursiops truncatus	67.12	0.00e+00	914.00
IUUC-Vda-129957	Verticillium dahliae	23.19	6.00e-26	113.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence