iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053992

Ensembl Protein ID

ENSLAFP00000011485.4

UniProt Accession

G3TBU9; G3TBU9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013714.4	ENSLAFT00000013721.4	ENSLAFP00000011485.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-27	95.4	153	190
UBD/Beta-Prp	8.60e-54	183.1	495	744

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELLKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           678999*****************************************9988878999************99997788889999****** PP
   S: 98   lslsfspsg.dklvsGshdrtirvwdletgqclee.......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtl 175
           ++++f  ++   ++s ++d+ i     ++ q  ++           ++ +   + ++ ++++++ ++ Dr vr+++    k++k+ +  
   Q: 584  TAIKFAGNRdIQMISCGADKSIYF---RSAQRASDglhfvrtHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGS 669
           ******98857899******9976...444444444444332111222233446677778***************99787888888888 PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           +g +++s  ++ +d++g++l++   d+++ + d+ +gecv ++ gh++ v+ ++f+ +  +l+++s D  ++iW l
   Q: 670  QG-DEGSLLKVHVDPSGTFLATSCSDKSISVMDFYSGECVAKMFGHSEIVTGMKFTYDCRHLITVSGDSCVFIWHL 744
           88.999999999**************************************************************43 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAALGPGGYA RNDAVEKLSS VTAGVPARRG QPSPPPAPPL CLRRRTRLTA APEDTVQSRV 60
SLEKVLGITA QNSSGLTCDP STGHVAYLAG CVVVILDPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TGGGCCCCGG AGGCTACGCG CGGAACGACG CGGTCGAGAA ACTGTCGTCT 60
GTCACCGCGG GGGTTCCGGC GAGGAGAGGC CAGCCCTCCC CGCCCCCCGC CCCACCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002469--Peptidase_S9B_N
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	80.11	0.00e+00	2341.00
IUUC-Atr-003165	Amborella trichopoda	34.33	8.00e-125	441.00
IUUC-Aca-004935	Anolis carolinensis	71.15	0.00e+00	1009.00
IUUC-Ath-007624	Arabidopsis thaliana	31.21	2.00e-94	340.00
IUUC-Afu-008757	Aspergillus fumigatus	22.59	1.00e-28	122.00
IUUC-Bta-013336	Bos taurus	77.11	0.00e+00	2168.00
IUUC-Cel-018592	Caenorhabditis elegans	29.11	9.00e-75	276.00
IUUC-Cja-019094	Callithrix jacchus	76.54	0.00e+00	2218.00
IUUC-Cfa-020529	Canis familiaris	79.61	0.00e+00	2327.00
IUUC-Cpo-021970	Cavia porcellus	83.86	0.00e+00	1616.00
IUUC-Cre-022999	Chlamydomonas reinhardtii	28.38	2.00e-13	71.60
IUUC-Csa-024161	Chlorocebus sabaeus	77.28	0.00e+00	2203.00
IUUC-Cho-024310	Choloepus hoffmanni	81.48	0.00e+00	1128.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	23.14	4.00e-24	107.00
IUUC-Dno-029933	Dasypus novemcinctus	78.22	0.00e+00	2183.00
IUUC-Dor-031147	Dipodomys ordii	74.62	0.00e+00	2023.00
IUUC-Eca-033675	Equus caballus	79.38	0.00e+00	2244.00
IUUC-Fca-035826	Felis catus	79.99	0.00e+00	2355.00
IUUC-Gma-043644	Glycine max	32.09	5.00e-104	372.00
IUUC-Ggo-045152	Gorilla gorilla	78.80	0.00e+00	2221.00
IUUC-Hsa-045891	Homo sapiens	78.99	0.00e+00	2222.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	91.49	0.00e+00	1540.00
IUUC-Lch-049669	Latimeria chalumnae	58.57	0.00e+00	993.00
IUUC-Loc-052488	Lepisosteus oculatus	58.17	0.00e+00	1014.00
IUUC-Mcc-054994	Macaca mulatta	78.55	0.00e+00	2199.00
IUUC-Meu-056815	Macropus eugenii	79.84	0.00e+00	1400.00
IUUC-Mtr-058383	Medicago truncatula	30.54	4.00e-51	195.00
IUUC-Mmr-060693	Microcebus murinus	77.95	0.00e+00	2158.00
IUUC-Mdo-063007	Monodelphis domestica	62.30	0.00e+00	1761.00
IUUC-Mmu-064067	Mus musculus	76.16	0.00e+00	2140.00
IUUC-Mpu-066532	Mustela putorius furo	80.22	0.00e+00	2377.00
IUUC-Mlu-066982	Myotis lucifugus	76.96	0.00e+00	2138.00
IUUC-Nle-070042	Nomascus leucogenys	82.12	0.00e+00	1897.00
IUUC-Opr-070397	Ochotona princeps	75.91	0.00e+00	2207.00
IUUC-Ocu-074274	Oryctolagus cuniculus	78.05	0.00e+00	2161.00
IUUC-Oga-088577	Otolemur garnettii	78.74	0.00e+00	2263.00
IUUC-Oar-090117	Ovis aries	76.09	0.00e+00	2125.00
IUUC-Ptr-090553	Pan troglodytes	78.99	0.00e+00	2252.00
IUUC-Pan-092559	Papio anubis	67.48	0.00e+00	1030.00
IUUC-Psi-093710	Pelodiscus sinensis	62.45	0.00e+00	1369.00
IUUC-Pab-098510	Pongo abelii	78.04	0.00e+00	2160.00
IUUC-Pop-099155	Populus trichocarpa	31.87	1.00e-99	358.00
IUUC-Pca-100323	Procavia capensis	72.79	0.00e+00	1353.00
IUUC-Pva-102895	Pteropus vampyrus	79.48	0.00e+00	2283.00
IUUC-Pte-104373	Pyrenophora teres	23.76	3.00e-27	117.00
IUUC-Pyt-104804	Pyrenophora triticirepentis	23.89	2.00e-27	118.00
IUUC-Rno-105598	Rattus norvegicus	76.08	0.00e+00	2149.00
IUUC-Sha-107013	Sarcophilus harrisii	64.50	0.00e+00	1763.00
IUUC-Smo-109134	Selaginella moellendorffii	36.86	4.00e-134	473.00
IUUC-Sly-110969	Solanum lycopersicum	30.09	3.00e-93	336.00
IUUC-Sar-113261	Sorex araneus	72.92	0.00e+00	2032.00
IUUC-Ssc-115317	Sus scrofa	78.95	0.00e+00	2219.00
IUUC-Tsy-118799	Tarsius syrichta	90.81	0.00e+00	857.00
IUUC-Tni-120316	Tetraodon nigroviridis	56.64	0.00e+00	790.00
IUUC-Tca-121475	Theobroma cacao	30.30	4.00e-96	346.00
IUUC-Tvi-122281	Trichoderma virens	23.56	7.00e-29	122.00
IUUC-Tbe-127555	Tupaia belangeri	92.50	0.00e+00	1007.00
IUUC-Ttr-128722	Tursiops truncatus	77.13	0.00e+00	2197.00
IUUC-Vpa-130392	Vicugna pacos	62.57	4.00e-96	345.00
IUUC-Vvi-131035	Vitis vinifera	33.89	6.00e-108	385.00
IUUC-Xtr-131789	Xenopus tropicalis	58.97	0.00e+00	981.00
IUUC-Yli-134437	Yarrowia lipolytica	26.42	5.00e-17	83.60

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence