iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Vda-129912

Ensembl Protein ID

EGY23176

UniProt Accession

G2X3M7; G2X3M7_VERDV

Genbank Protein ID

EGY23176.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

DS572702

Gene Name

VDAG_04614

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
VDAG_04614	EGY23176	EGY23176

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	2.00e-57	194.1	4	269

Active Site

Position(s)	Description	Evidence
87	Nucleophile	{ECO:0000256\|PIRSR:PIRSR038120-1}
163	Proton donor	{ECO:0000256\|PIRSR:PIRSR038120-1}

Domain Profile

DUB/UCH

   S: 7    ewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCatyAllsv 107
           +w ++esd+g+ft l+e++gvk++ q+eel  L p+ l+ + +pv+g+++lF++ ++    r +       e+ ded+ + +ffa q+i+N+C+t+Allsv
   Q: 4    GWNTIESDAGVFTYLLENLGVKGV-QFEELLTLSPDDLAPL-QPVYGIIFLFRYPSEGLPPRPK-------ESYDEDAAERLFFARQTIQNACGTQALLSV 95
           8***********************.****************.9***********9999999844.......699*************************** PP
   S: 108  llncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrlyeldglkpfPldlgkkke 208
           + n +++ +d+G+ l +++e+  a  pe +++al+n++ ++ +hns+a++ ++  +++++++     ++afhfv+y  i+g+lyeldgl+p+P+ +g ++ 
   Q: 96   VMNKNNE-VDIGDRLGEFREFAMALPPEFRGEALSNSELIREVHNSFAKSSPFVDETQRGDE---GGEDAFHFVAYSSIGGKLYELDGLQPAPISHGDCTP 192
           ****999.6*******************************************9887766444...3899*****************************776 PP
   S: 209  teelkdklkvvraflerikllesdeirfnllaivadrrviktlrlnvlkidkeLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifi 309
           + e+  k++ +    +r+  + s eirfn+la+v d r++                      + e   +++++ e ekr+++  ++  R++n+++f  + +
   Q: 193  D-EFPVKISGIL--SDRVATYASSEIRFNVLAMVRDPRIA----------------------AAEIGDQETIARESEKRRQWQWENALRRHNFVGFAGEVM 268
           5.5678899998..9*********************9973......................333344566777888888888888888888888766655 PP
   S: 310  k 310
           k
   Q: 269  K 269
           5 PP

Organism

Verticillium dahliae

Protein Sequence
(Fasta)

MSGGWNTIES DAGVFTYLLE NLGVKGVQFE ELLTLSPDDL APLQPVYGII FLFRYPSEGL 60
PPRPKESYDE DAAERLFFAR QTIQNACGTQ ALLSVVMNKN NEVDIGDRLG EFREFAMALP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGGCG GATGGAACAC GAGTATGCCA CAGTCGTTCG CTTTTCTCCT CCAATATTTC 60
GCTGACATAG TACCTCCTCG CAGTCGAGTC GGACGCCGGC GTCTTCACGT ACCTCCTCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR017390--Ubiquitinyl_hydrolase_UCH37

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0034399--C:nuclear periphery
GO:0031595--C:nuclear proteasome complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

vda:VDAG_04614

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000936	Aegilops tauschii	38.29	2.00e-57	214.00
IUUC-Aml-001866	Ailuropoda melanoleuca	37.05	4.00e-54	202.00
IUUC-Atr-002966	Amborella trichopoda	35.33	9.00e-49	185.00
IUUC-Apl-003306	Anas platyrhynchos	34.46	7.00e-47	179.00
IUUC-Aca-004763	Anolis carolinensis	37.38	4.00e-55	206.00
IUUC-Aly-005581	Arabidopsis lyrata	37.78	2.00e-51	194.00
IUUC-Ath-007283	Arabidopsis thaliana	37.14	1.00e-53	201.00
IUUC-Ago-007999	Ashbya gossypii	38.85	2.00e-43	167.00
IUUC-Acl-008231	Aspergillus clavatus	55.70	1.00e-87	314.00
IUUC-Afl-008557	Aspergillus flavus	56.57	7.00e-89	318.00
IUUC-Afu-008988	Aspergillus fumigatus	55.23	1.00e-85	307.00
IUUC-Ani-009420	Aspergillus nidulans	52.10	6.00e-87	311.00
IUUC-Ang-009859	Aspergillus niger	54.66	6.00e-85	305.00
IUUC-Aor-010145	Aspergillus oryzae	56.57	7.00e-89	318.00
IUUC-Ate-010347	Aspergillus terreus	50.62	6.00e-82	295.00
IUUC-Ame-010791	Astyanax mexicanus	36.18	2.00e-54	204.00
IUUC-Bgr-012298	Blumeria graminis	58.00	2.00e-98	350.00
IUUC-Bta-013251	Bos taurus	37.17	4.00e-54	203.00
IUUC-Bci-013786	Botrytis cinerea	63.07	3.00e-109	386.00
IUUC-Bdi-014132	Brachypodium distachyon	43.20	2.00e-53	200.00
IUUC-Bol-015611	Brassica oleracea	37.58	1.00e-52	198.00
IUUC-Bra-017769	Brassica rapa	38.22	1.00e-52	198.00
IUUC-Cel-018604	Caenorhabditis elegans	38.04	7.00e-52	195.00
IUUC-Cja-019768	Callithrix jacchus	34.64	5.00e-49	186.00
IUUC-Cfa-020207	Canis familiaris	37.05	4.00e-54	202.00
IUUC-Cpo-021925	Cavia porcellus	35.74	4.00e-49	186.00
IUUC-Cre-022919	Chlamydomonas reinhardtii	41.04	1.00e-58	218.00
IUUC-Csa-023958	Chlorocebus sabaeus	36.96	2.00e-54	204.00
IUUC-Cho-024928	Choloepus hoffmanni	42.31	4.00e-12	63.50
IUUC-Cin-025771	Ciona intestinalis	33.55	2.00e-49	187.00
IUUC-Csv-026149	Ciona savignyi	34.42	9.00e-50	188.00
IUUC-Cgl-026424	Colletotrichum gloeosporioides	73.91	3.00e-129	452.00
IUUC-Cne-026955	Cryptococcus neoformans	36.96	1.00e-45	175.00
IUUC-Cme-027104	Cyanidioschyzon merolae	36.64	5.00e-47	179.00
IUUC-Dre-027409	Danio rerio	36.39	3.00e-53	199.00
IUUC-Dno-028921	Dasypus novemcinctus	37.05	7.00e-54	202.00
IUUC-Dor-030891	Dipodomys ordii	39.61	7.00e-23	100.00
IUUC-Dse-031170	Dothistroma septosporum	54.43	2.00e-92	330.00
IUUC-Dme-031677	Drosophila melanogaster	36.86	8.00e-51	192.00
IUUC-Ete-032646	Echinops telfairi	36.68	1.00e-26	113.00
IUUC-Eca-033776	Equus caballus	36.27	8.00e-48	182.00
IUUC-Eeu-035305	Erinaceus europaeus	37.63	2.00e-29	120.00
IUUC-Fca-035846	Felis catus	34.04	1.00e-49	188.00
IUUC-Fal-037597	Ficedula albicollis	35.92	8.00e-48	182.00
IUUC-Fox-037670	Fusarium oxysporum	66.67	4.00e-107	379.00
IUUC-Fso-038243	Fusarium solani	65.90	7.00e-105	371.00
IUUC-Gmo-038499	Gadus morhua	35.53	1.00e-48	185.00
IUUC-Ggr-039975	Gaeumannomyces graminis	64.75	2.00e-94	337.00
IUUC-Gga-040904	Gallus gallus	37.70	8.00e-55	205.00
IUUC-Gac-042058	Gasterosteus aculeatus	37.50	2.00e-55	207.00
IUUC-Gma-043030	Glycine max	37.96	5.00e-54	202.00
IUUC-Ggo-044699	Gorilla gorilla	42.61	3.00e-52	196.00
IUUC-Hsa-046227	Homo sapiens	36.84	1.00e-54	204.00
IUUC-Hvu-047359	Hordeum vulgare	37.97	3.00e-57	213.00
IUUC-Itr-048989	Ictidomys tridecemlineatus	33.63	6.00e-49	186.00
IUUC-Lch-049829	Latimeria chalumnae	36.84	5.00e-55	206.00
IUUC-Lpe-050899	Leersia perrieri	38.46	5.00e-53	199.00
IUUC-Loc-052264	Lepisosteus oculatus	36.72	9.00e-54	201.00
IUUC-Lma-053110	Leptosphaeria maculans	64.71	6.00e-97	345.00
IUUC-Laf-053639	Loxodonta africana	37.05	4.00e-54	202.00
IUUC-Mcc-055506	Macaca mulatta	36.96	2.00e-54	204.00
IUUC-Meu-056267	Macropus eugenii	37.45	3.00e-34	138.00
IUUC-Mor-057001	Magnaporthe oryzae	62.05	2.00e-99	353.00
IUUC-Mpo-057608	Magnaporthe poae	65.59	4.00e-61	225.00
IUUC-Mtr-057731	Medicago truncatula	44.00	3.00e-55	206.00
IUUC-Mla-059016	Melampsora laricipopulina	45.10	2.00e-43	167.00
IUUC-Mga-060178	Meleagris gallopavo	36.97	2.00e-48	184.00
IUUC-Mvi-060353	Microbotryum violaceum	37.10	3.00e-51	193.00
IUUC-Mmr-060738	Microcebus murinus	37.05	4.00e-54	202.00
IUUC-Mdo-062266	Monodelphis domestica	43.00	1.00e-44	171.00
IUUC-Mmu-063619	Mus musculus	37.17	1.00e-54	204.00
IUUC-Mac-065301	Musa acuminata	40.40	6.00e-57	212.00
IUUC-Mpu-066058	Mustela putorius furo	37.05	4.00e-54	202.00
IUUC-Mlu-067292	Myotis lucifugus	36.63	4.00e-54	202.00
IUUC-Nfi-068275	Neosartorya fischeri	55.23	1.00e-93	333.00
IUUC-Ncr-068713	Neurospora crassa	62.89	6.00e-113	398.00
IUUC-Nle-069013	Nomascus leucogenys	36.96	5.00e-54	202.00
IUUC-Opr-070628	Ochotona princeps	32.42	2.00e-45	174.00
IUUC-Ont-072688	Oreochromis niloticus	37.05	7.00e-54	202.00
IUUC-Oan-073004	Ornithorhynchus anatinus	42.86	7.00e-46	175.00
IUUC-Ocu-074303	Oryctolagus cuniculus	36.72	3.00e-53	201.00
IUUC-Oba-075002	Oryza barthii	36.68	5.00e-54	202.00
IUUC-Obr-076392	Oryza brachyantha	35.74	3.00e-52	196.00
IUUC-Ogl-077271	Oryza glaberrima	36.68	5.00e-54	202.00
IUUC-Ogu-078493	Oryza glumaepatula	36.68	8.00e-54	202.00
IUUC-Oin-080084	Oryza indica	36.68	8.00e-54	202.00
IUUC-Olo-080803	Oryza longistaminata	36.68	9.00e-54	201.00
IUUC-Ome-081146	Oryza meridionalis	36.68	1.00e-53	201.00
IUUC-Oni-082146	Oryza nivara	36.68	8.00e-54	202.00
IUUC-Opu-083633	Oryza punctata	36.68	2.00e-53	201.00
IUUC-Oru-084789	Oryza rufipogon	36.68	8.00e-54	202.00
IUUC-Osa-086196	Oryza sativa	36.68	8.00e-54	202.00
IUUC-Ola-087126	Oryzias latipes	37.17	3.00e-55	206.00
IUUC-Olu-087665	Ostreococcus lucimarinus	39.93	2.00e-53	201.00
IUUC-Oga-089140	Otolemur garnettii	34.14	3.00e-50	190.00
IUUC-Oar-090296	Ovis aries	36.72	2.00e-52	197.00
IUUC-Ptr-090566	Pan troglodytes	36.84	1.00e-54	204.00
IUUC-Pan-092052	Papio anubis	36.96	2.00e-54	204.00
IUUC-Psi-093723	Pelodiscus sinensis	35.69	1.00e-48	184.00
IUUC-Pma-094568	Petromyzon marinus	40.76	4.00e-41	159.00
IUUC-Pno-095120	Phaeosphaeria nodorum	62.38	1.00e-102	363.00
IUUC-Ppa-095761	Physcomitrella patens	42.23	4.00e-51	193.00
IUUC-Pfo-096210	Poecilia formosa	37.50	4.00e-55	206.00
IUUC-Pab-098463	Pongo abelii	36.84	3.00e-54	203.00
IUUC-Pop-099423	Populus trichocarpa	37.54	6.00e-54	202.00
IUUC-Pca-100108	Procavia capensis	42.06	3.00e-49	187.00
IUUC-Ppe-101176	Prunus persica	38.27	1.00e-52	198.00
IUUC-Pva-102629	Pteropus vampyrus	42.67	5.00e-50	189.00
IUUC-Pgr-103419	Puccinia graminis	41.13	4.00e-46	176.00
IUUC-Pte-104207	Pyrenophora teres	65.48	1.00e-55	207.00
IUUC-Pyt-104471	Pyrenophora triticirepentis	61.39	6.00e-105	371.00
IUUC-Rno-105579	Rattus norvegicus	32.49	9.00e-44	168.00
IUUC-Sha-106894	Sarcophilus harrisii	35.71	3.00e-42	163.00
IUUC-Sja-107732	Schizosaccharomyces japonicus	44.78	3.00e-71	259.00
IUUC-Spo-108371	Schizosaccharomyces pombe	48.03	2.00e-77	280.00
IUUC-Ssl-108467	Sclerotinia sclerotiorum	64.62	5.00e-94	335.00
IUUC-Smo-109396	Selaginella moellendorffii	38.10	5.00e-52	196.00
IUUC-Sit-110630	Setaria italica	43.28	1.00e-53	201.00
IUUC-Sly-110972	Solanum lycopersicum	35.95	6.00e-50	189.00
IUUC-Stu-112185	Solanum tuberosum	37.96	2.00e-57	214.00
IUUC-Sar-113294	Sorex araneus	32.83	3.00e-44	170.00
IUUC-Sbi-113951	Sorghum bicolor	43.20	7.00e-54	202.00
IUUC-Ssc-115501	Sus scrofa	35.84	3.00e-49	186.00
IUUC-Tgu-117152	Taeniopygia guttata	35.92	8.00e-48	182.00
IUUC-Tru-118388	Takifugu rubripes	37.17	1.00e-54	205.00
IUUC-Tsy-119109	Tarsius syrichta	37.05	4.00e-54	202.00
IUUC-Tni-120048	Tetraodon nigroviridis	37.17	6.00e-55	205.00
IUUC-Tca-121750	Theobroma cacao	37.23	4.00e-55	206.00
IUUC-Tre-122130	Trichoderma reesei	63.75	4.00e-110	389.00
IUUC-Tvi-122284	Trichoderma virens	65.32	9.00e-103	364.00
IUUC-Tae-124082	Triticum aestivum	38.29	2.00e-57	214.00
IUUC-Tur-126366	Triticum urartu	38.99	2.00e-36	144.00
IUUC-Tme-127187	Tuber melanosporum	59.60	6.00e-103	365.00
IUUC-Tbe-127705	Tupaia belangeri	39.09	3.00e-33	134.00
IUUC-Ttr-128867	Tursiops truncatus	37.71	9.00e-41	158.00
IUUC-Vpa-130552	Vicugna pacos	42.86	2.00e-45	174.00
IUUC-Vvi-130881	Vitis vinifera	37.96	3.00e-51	193.00
IUUC-Xtr-131934	Xenopus tropicalis	36.84	5.00e-53	199.00
IUUC-Xma-133312	Xiphophorus maculatus	37.50	3.00e-55	206.00
IUUC-Yli-134487	Yarrowia lipolytica	45.48	2.00e-70	257.00
IUUC-Zma-135462	Zea mays	39.04	1.00e-42	164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence