iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027681

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 23

Genbank Nucleotide ID

BX321905

Gene Name

klhl23

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000078475.3	ENSDART00000114463.2	ENSDARP00000099374.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.00e-12	49.1	37	100
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.00e-06	27.1	136	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           D+ l+   g+ f++hk+vL+a+Ss+F+ +f+ +++e+  ++++++  v+ e + al+ ++Yt k+
   Q: 37   DIALQSSsGQLFHCHKAVLSARSSYFKVMFTLDMRERA-NDTINLPCVDGEILGALVTYVYTAKI 100
           77777778****************************98.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclg+ +fA+l+ c+ L  aal+ il+ F
   Q: 136  VDNCLGMHSFAELHVCSALERAALRIILSRF 166
           69**********************9888888 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MSGNAQSGYS YDFYDASHPS EVLEALHEFH NSGLFTDIAL QSSSGQLFHC HKAVLSARSS 60
YFKVMFTLDM RERANDTINL PCVDGEILGA LVTYVYTAKI GITQNNVQRL LEAADLLQFN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTAAAACGTG TACACTAGCT AGTATTGTGT CTCAGTTCAG TCGGAAAGCG GTAAAATTGT 60
GTCTTATTAA TGCTGGGATG CTCGACTGGT CACATAGGCT GAAAGACGCG GCTGTGTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

dre:559613

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001639	Ailuropoda melanoleuca	59.71	0.00e+00	734.00
IUUC-Apl-003948	Anas platyrhynchos	65.11	0.00e+00	722.00
IUUC-Aca-005045	Anolis carolinensis	59.46	0.00e+00	733.00
IUUC-Ame-011013	Astyanax mexicanus	73.52	0.00e+00	864.00
IUUC-Bta-013159	Bos taurus	59.71	0.00e+00	732.00
IUUC-Cja-018886	Callithrix jacchus	59.46	0.00e+00	736.00
IUUC-Cfa-020205	Canis familiaris	59.82	0.00e+00	739.00
IUUC-Cpo-022295	Cavia porcellus	59.64	0.00e+00	738.00
IUUC-Cho-025089	Choloepus hoffmanni	56.89	4.00e-163	567.00
IUUC-Dno-029078	Dasypus novemcinctus	56.24	1.00e-162	566.00
IUUC-Ete-033011	Echinops telfairi	53.83	4.00e-179	621.00
IUUC-Eca-033213	Equus caballus	59.82	0.00e+00	740.00
IUUC-Fca-035884	Felis catus	59.64	0.00e+00	738.00
IUUC-Fal-036897	Ficedula albicollis	61.94	0.00e+00	748.00
IUUC-Gmo-038594	Gadus morhua	62.68	0.00e+00	754.00
IUUC-Ggr-039827	Gaeumannomyces graminis	30.95	2.00e-06	45.80
IUUC-Gga-040791	Gallus gallus	62.21	0.00e+00	756.00
IUUC-Gac-042512	Gasterosteus aculeatus	65.30	0.00e+00	785.00
IUUC-Ggo-044837	Gorilla gorilla	60.18	0.00e+00	740.00
IUUC-Hsa-046231	Homo sapiens	60.18	0.00e+00	741.00
IUUC-Itr-048084	Ictidomys tridecemlineatus	60.00	0.00e+00	740.00
IUUC-Lch-050412	Latimeria chalumnae	65.48	0.00e+00	793.00
IUUC-Loc-052033	Lepisosteus oculatus	68.97	0.00e+00	831.00
IUUC-Laf-053908	Loxodonta africana	60.18	0.00e+00	741.00
IUUC-Mcc-054734	Macaca mulatta	60.18	0.00e+00	741.00
IUUC-Meu-055982	Macropus eugenii	61.07	0.00e+00	749.00
IUUC-Mga-059670	Meleagris gallopavo	61.03	0.00e+00	746.00
IUUC-Mmr-060692	Microcebus murinus	60.18	0.00e+00	742.00
IUUC-Mdo-062419	Monodelphis domestica	61.07	0.00e+00	748.00
IUUC-Mmu-063752	Mus musculus	60.71	0.00e+00	745.00
IUUC-Mpu-066515	Mustela putorius furo	59.64	0.00e+00	738.00
IUUC-Mlu-068004	Myotis lucifugus	58.96	0.00e+00	723.00
IUUC-Nle-069163	Nomascus leucogenys	60.18	0.00e+00	741.00
IUUC-Opr-070823	Ochotona princeps	55.14	9.00e-159	553.00
IUUC-Ont-071629	Oreochromis niloticus	66.67	0.00e+00	803.00
IUUC-Oan-072841	Ornithorhynchus anatinus	60.00	0.00e+00	738.00
IUUC-Ocu-074300	Oryctolagus cuniculus	59.82	0.00e+00	740.00
IUUC-Ola-087025	Oryzias latipes	61.92	0.00e+00	756.00
IUUC-Oga-088442	Otolemur garnettii	59.56	0.00e+00	713.00
IUUC-Oar-089237	Ovis aries	59.36	0.00e+00	729.00
IUUC-Ptr-091541	Pan troglodytes	60.18	0.00e+00	741.00
IUUC-Psi-093748	Pelodiscus sinensis	61.07	0.00e+00	751.00
IUUC-Pma-094302	Petromyzon marinus	44.06	1.00e-96	347.00
IUUC-Pfo-097039	Poecilia formosa	66.25	0.00e+00	768.00
IUUC-Pab-098280	Pongo abelii	60.18	0.00e+00	741.00
IUUC-Pca-100840	Procavia capensis	53.39	0.00e+00	635.00
IUUC-Pva-102152	Pteropus vampyrus	60.00	0.00e+00	740.00
IUUC-Rno-105710	Rattus norvegicus	60.36	0.00e+00	739.00
IUUC-Sha-106991	Sarcophilus harrisii	60.71	0.00e+00	747.00
IUUC-Sar-112931	Sorex araneus	59.82	0.00e+00	741.00
IUUC-Ssc-116016	Sus scrofa	59.18	0.00e+00	730.00
IUUC-Tgu-116999	Taeniopygia guttata	61.85	0.00e+00	749.00
IUUC-Tsy-119071	Tarsius syrichta	60.00	0.00e+00	737.00
IUUC-Tni-120149	Tetraodon nigroviridis	61.92	0.00e+00	720.00
IUUC-Tbe-127651	Tupaia belangeri	60.00	0.00e+00	741.00
IUUC-Ttr-128402	Tursiops truncatus	60.00	0.00e+00	740.00
IUUC-Vpa-130186	Vicugna pacos	58.39	0.00e+00	722.00
IUUC-Xtr-132379	Xenopus tropicalis	59.64	0.00e+00	738.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence