iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019243

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACFV01139445

Gene Name

TRAF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000015047.2	ENSCJAT00000029309.2	ENSCJAP00000027736.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-27	95.1	394	424
UBD/Beta-Prp	1.20e-54	186.5	427	650

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDl 30
           gH+++v+cl+  s + l+sGs D+tikvWD+
   Q: 394  GHQGPVWCLCVySMGDLLSGSSDKTIKVWDT 424
           8********97677889*************6 PP

UBD/Beta-Prp

   S: 41   tgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdl.etgqc 128
           t k+ ++l+gh++ v a++++     l +gs D ti vwd+++ + v t+++h++ v++l +s   + l sGs  + i+vwd+  t+ +
   Q: 427  TYKCQKTLEGHDGIVLALCIQGC--KLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELK 510
           568899***************99..6*********************************99999..9******.9*******7368888 PP
   S: 129  leetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrt 217
           l++ l+g +++v+ +v  +  ++l sGs+ +t+++Wd++t ++++ l+    +svys++++    ++v g + + + +wd++++e vrt
   Q: 511  LKKELTGLNHWVRALVAAQ--SYLYSGSY-QTIKIWDIRTLDCIHVLQT-SGGSVYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRT 593
           888**************99..*******9.79***************99.***********9..8************************ PP
   S: 218  lnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav 272
           l+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv++ av
   Q: 594  LTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAV 650
           ***********99888************************************99987 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSSGKSARYN RFSGGSTNLP TQDITTGSRM ETTFGPSFSA VTTVTKADGT STYKQHCRTP 60
SSSSTLAYSP RDEEDSMPPI STPRRSDSAI SVRSLHSESS MSLRSTFSLP EEEEEPEPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCCCGGC CGGCGGCCGA GGGGGCATCA TGAAGCGGGC CGGCGGCGCT ACGGCTCCCA 60
GGTGGCCGCG GGCGGGTGAG TGTCCCCGCG ACGCGCCCGG CCCGGGGCCG CGCGGTGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	96.04	0.00e+00	1212.00
IUUC-Apl-004098	Anas platyrhynchos	93.92	0.00e+00	1153.00
IUUC-Aca-004852	Anolis carolinensis	87.65	0.00e+00	969.00
IUUC-Ame-011275	Astyanax mexicanus	82.60	0.00e+00	926.00
IUUC-Bta-013153	Bos taurus	96.48	0.00e+00	1221.00
IUUC-Cfa-020036	Canis familiaris	96.94	0.00e+00	1239.00
IUUC-Cpo-022194	Cavia porcellus	96.33	0.00e+00	1231.00
IUUC-Csa-023363	Chlorocebus sabaeus	97.86	0.00e+00	1251.00
IUUC-Cin-025279	Ciona intestinalis	58.39	0.00e+00	767.00
IUUC-Csv-026163	Ciona savignyi	64.18	0.00e+00	742.00
IUUC-Dre-027998	Danio rerio	90.24	0.00e+00	1071.00
IUUC-Dno-029356	Dasypus novemcinctus	94.20	4.00e-128	449.00
IUUC-Dor-030750	Dipodomys ordii	93.88	0.00e+00	1180.00
IUUC-Eca-033671	Equus caballus	80.85	0.00e+00	939.00
IUUC-Eeu-034765	Erinaceus europaeus	96.92	9.00e-157	546.00
IUUC-Fca-035843	Felis catus	96.94	0.00e+00	1239.00
IUUC-Fal-037237	Ficedula albicollis	92.35	0.00e+00	1191.00
IUUC-Gmo-038779	Gadus morhua	80.87	0.00e+00	976.00
IUUC-Gga-040579	Gallus gallus	91.90	0.00e+00	1184.00
IUUC-Gac-042233	Gasterosteus aculeatus	85.62	0.00e+00	1080.00
IUUC-Ggo-045147	Gorilla gorilla	97.55	0.00e+00	1248.00
IUUC-Hsa-046117	Homo sapiens	97.71	0.00e+00	1250.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	96.79	0.00e+00	1239.00
IUUC-Lch-050593	Latimeria chalumnae	90.08	0.00e+00	1138.00
IUUC-Loc-052444	Lepisosteus oculatus	88.77	0.00e+00	1165.00
IUUC-Laf-053499	Loxodonta africana	90.27	0.00e+00	1127.00
IUUC-Mcc-055038	Macaca mulatta	98.01	0.00e+00	1253.00
IUUC-Meu-056610	Macropus eugenii	93.81	0.00e+00	925.00
IUUC-Mga-060183	Meleagris gallopavo	91.62	0.00e+00	1180.00
IUUC-Mmr-061133	Microcebus murinus	95.52	0.00e+00	1196.00
IUUC-Mdo-062312	Monodelphis domestica	94.96	0.00e+00	1212.00
IUUC-Mmu-063844	Mus musculus	95.72	0.00e+00	1190.00
IUUC-Mpu-066552	Mustela putorius furo	96.79	0.00e+00	1214.00
IUUC-Mlu-067719	Myotis lucifugus	95.87	0.00e+00	1194.00
IUUC-Nle-070045	Nomascus leucogenys	98.19	0.00e+00	1162.00
IUUC-Opr-070927	Ochotona princeps	93.58	0.00e+00	1176.00
IUUC-Ont-072680	Oreochromis niloticus	85.40	0.00e+00	1099.00
IUUC-Oan-073521	Ornithorhynchus anatinus	94.00	2.00e-52	196.00
IUUC-Ola-087454	Oryzias latipes	86.06	0.00e+00	1134.00
IUUC-Oga-088380	Otolemur garnettii	96.64	0.00e+00	1231.00
IUUC-Oar-089558	Ovis aries	78.84	0.00e+00	960.00
IUUC-Ptr-091606	Pan troglodytes	97.55	0.00e+00	1248.00
IUUC-Pan-092227	Papio anubis	98.01	0.00e+00	1253.00
IUUC-Psi-093853	Pelodiscus sinensis	85.35	0.00e+00	1005.00
IUUC-Pma-094541	Petromyzon marinus	80.70	4.00e-152	530.00
IUUC-Pfo-096237	Poecilia formosa	84.47	0.00e+00	1085.00
IUUC-Pab-097589	Pongo abelii	97.71	0.00e+00	1249.00
IUUC-Pca-100375	Procavia capensis	93.12	0.00e+00	1146.00
IUUC-Pva-102434	Pteropus vampyrus	96.94	0.00e+00	1233.00
IUUC-Rno-105443	Rattus norvegicus	96.18	0.00e+00	1197.00
IUUC-Sha-106517	Sarcophilus harrisii	94.66	0.00e+00	1207.00
IUUC-Ssc-115990	Sus scrofa	95.87	0.00e+00	1220.00
IUUC-Tgu-117222	Taeniopygia guttata	92.20	0.00e+00	1191.00
IUUC-Tru-118392	Takifugu rubripes	87.99	0.00e+00	1094.00
IUUC-Tni-120220	Tetraodon nigroviridis	87.42	0.00e+00	1085.00
IUUC-Tbe-128045	Tupaia belangeri	98.91	3.00e-152	532.00
IUUC-Ttr-128203	Tursiops truncatus	93.27	0.00e+00	1169.00
IUUC-Xtr-132043	Xenopus tropicalis	90.37	0.00e+00	1192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence