iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037237

Ensembl Protein ID

ENSFALP00000003730.1

UniProt Accession

U3JLS6; U3JLS6_FICAL

Genbank Protein ID

ENSFALP00000003730

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010720

Gene Name

TRAF7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000003582.1	ENSFALT00000003745.1	ENSFALP00000003730.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.50e-32	107.9	394	425
UBD/Beta-Prp	1.50e-49	168.5	392	670

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDl 30
           gH+++v+cl+      +ll sGs D+tikvWD+
   Q: 394  GHQGPVWCLCVysiG-DLLFSGSSDKTIKVWDT 425
           8********965643.89**************6 PP

UBD/Beta-Prp

   S: 5    lkghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           + gh+   + c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++ +   l +gs D ti vwd+++ + v t+++
   Q: 392  FVGHQGP-VWCLCVYSIGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGN--KLYSGSADCTIIVWDIQNLQKVNTIRA 477
           5556655.5559999*******************846678899****************9..6************************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
           h++ v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v ++  n+l sGs+ +t+++Wd+++ ++++ l+    
   Q: 478  HDNPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVASQ--NYLYSGSY-QTIKIWDIRNLECVHVLQT-SG 559
           *******99999..9******.9*******7368888888**************99..*******9.79***************99.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssv 267
           +svys++++    ++v g + + + +wd++t+e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv
   Q: 560  GSVYSIAVTN--HHIVCGTYENLIHVWDIETKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSV 646
           *********9..8***********************************99888************************************ PP
   S: 268  isvavlsfgdnvlvlgsedskvniwkl 294
           ++ av   ++  l++g+ ds+v++w +
   Q: 647  TALAV---SRGRLFSGAVDSTVKVWTC 670
           ****9...*****************86 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MSSSKNARYN RFSSGTTNIT ASENTNGTRM ETTFGPAFSA VTTITKADGT NTFKQHRRTP 60
SSSSTLTYSP RDEDDGMPPI STPRRSDSAI SVRSLHSESN MSLRSTFSLH EEEEEPEPLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCAAGCTTC CCATGACTAA CAGATGCTGG CCTAGATTAT GAGCTCAAGC AAGAACGCTC 60
GCTACAATCG TTTCTCCAGT GGCACAACAA ACATCACTGC TTCTGAAAAC ACCAACGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00400--WD40
PF13445--zf-RING_UBOX

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway

KEGG

fab:101808366

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001971	Ailuropoda melanoleuca	92.87	0.00e+00	1223.00
IUUC-Apl-004098	Anas platyrhynchos	99.53	0.00e+00	1254.00
IUUC-Aca-004852	Anolis carolinensis	92.11	0.00e+00	1018.00
IUUC-Ame-011275	Astyanax mexicanus	85.25	0.00e+00	964.00
IUUC-Bta-013153	Bos taurus	93.28	0.00e+00	1228.00
IUUC-Cja-019243	Callithrix jacchus	92.35	0.00e+00	1188.00
IUUC-Cfa-020036	Canis familiaris	93.58	0.00e+00	1239.00
IUUC-Cpo-022194	Cavia porcellus	93.25	0.00e+00	1230.00
IUUC-Csa-023363	Chlorocebus sabaeus	93.58	0.00e+00	1237.00
IUUC-Cin-025279	Ciona intestinalis	58.98	0.00e+00	806.00
IUUC-Csv-026163	Ciona savignyi	64.36	0.00e+00	778.00
IUUC-Dre-027998	Danio rerio	92.98	0.00e+00	1144.00
IUUC-Dno-029356	Dasypus novemcinctus	92.41	8.00e-127	445.00
IUUC-Dor-030750	Dipodomys ordii	90.75	0.00e+00	1186.00
IUUC-Eca-033671	Equus caballus	78.12	0.00e+00	952.00
IUUC-Eeu-034765	Erinaceus europaeus	95.07	6.00e-163	567.00
IUUC-Fca-035843	Felis catus	93.43	0.00e+00	1239.00
IUUC-Gmo-038779	Gadus morhua	83.36	0.00e+00	1033.00
IUUC-Gga-040579	Gallus gallus	98.51	0.00e+00	1300.00
IUUC-Gac-042233	Gasterosteus aculeatus	87.80	0.00e+00	1148.00
IUUC-Gma-042914	Glycine max	27.54	1.00e-19	90.50
IUUC-Ggo-045147	Gorilla gorilla	93.13	0.00e+00	1231.00
IUUC-Hsa-046117	Homo sapiens	93.28	0.00e+00	1233.00
IUUC-Itr-048899	Ictidomys tridecemlineatus	93.28	0.00e+00	1237.00
IUUC-Lch-050593	Latimeria chalumnae	94.63	0.00e+00	1230.00
IUUC-Loc-052444	Lepisosteus oculatus	92.46	0.00e+00	1249.00
IUUC-Laf-053499	Loxodonta africana	88.65	0.00e+00	1155.00
IUUC-Mcc-055038	Macaca mulatta	93.43	0.00e+00	1235.00
IUUC-Meu-056610	Macropus eugenii	93.01	0.00e+00	929.00
IUUC-Mtr-057641	Medicago truncatula	27.73	2.00e-20	93.20
IUUC-Mga-060183	Meleagris gallopavo	98.07	0.00e+00	1294.00
IUUC-Mmr-061133	Microcebus murinus	91.36	0.00e+00	1159.00
IUUC-Mdo-062312	Monodelphis domestica	94.93	0.00e+00	1254.00
IUUC-Mmu-063844	Mus musculus	93.28	0.00e+00	1207.00
IUUC-Mpu-066552	Mustela putorius furo	93.28	0.00e+00	1219.00
IUUC-Mlu-067719	Myotis lucifugus	93.13	0.00e+00	1202.00
IUUC-Nle-070045	Nomascus leucogenys	94.88	0.00e+00	1169.00
IUUC-Opr-070927	Ochotona princeps	91.04	0.00e+00	1194.00
IUUC-Ont-072680	Oreochromis niloticus	87.32	0.00e+00	1172.00
IUUC-Oan-073521	Ornithorhynchus anatinus	94.00	3.00e-52	195.00
IUUC-Ogu-077987	Oryza glumaepatula	25.43	4.00e-19	89.40
IUUC-Oru-085210	Oryza rufipogon	25.20	2.00e-19	90.10
IUUC-Ola-087454	Oryzias latipes	89.33	0.00e+00	1214.00
IUUC-Oga-088380	Otolemur garnettii	93.43	0.00e+00	1237.00
IUUC-Oar-089558	Ovis aries	76.42	0.00e+00	967.00
IUUC-Ptr-091606	Pan troglodytes	93.13	0.00e+00	1231.00
IUUC-Pan-092227	Papio anubis	93.43	0.00e+00	1235.00
IUUC-Psi-093853	Pelodiscus sinensis	90.13	0.00e+00	1067.00
IUUC-Pma-094541	Petromyzon marinus	81.33	2.00e-157	547.00
IUUC-Pfo-096237	Poecilia formosa	88.01	0.00e+00	1165.00
IUUC-Pab-097589	Pongo abelii	93.28	0.00e+00	1233.00
IUUC-Pca-100375	Procavia capensis	91.14	0.00e+00	1168.00
IUUC-Pva-102434	Pteropus vampyrus	93.88	0.00e+00	1242.00
IUUC-Rno-105443	Rattus norvegicus	93.73	0.00e+00	1212.00
IUUC-Sha-106517	Sarcophilus harrisii	94.64	0.00e+00	1248.00
IUUC-Ssc-115990	Sus scrofa	92.84	0.00e+00	1230.00
IUUC-Tgu-117222	Taeniopygia guttata	98.35	0.00e+00	1293.00
IUUC-Tru-118392	Takifugu rubripes	90.87	0.00e+00	1172.00
IUUC-Tni-120220	Tetraodon nigroviridis	90.05	0.00e+00	1164.00
IUUC-Tbe-128045	Tupaia belangeri	96.53	2.00e-158	551.00
IUUC-Ttr-128203	Tursiops truncatus	89.85	0.00e+00	1172.00
IUUC-Xtr-132043	Xenopus tropicalis	93.88	0.00e+00	1281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence