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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063844
UUCD1 version UUC-MuM-00852
Ensembl Protein ID ENSMUSP00000134759.1
UniProt Accession F8WJF7; F8WJF7_MOUSE
Genbank Protein ID ENSMUSP00000085812
Protein Name E3 ubiquitin-protein ligase TRAF7
Genbank Nucleotide ID AC132367
Gene Name Traf7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000052752.15 ENSMUST00000176652.7 ENSMUSP00000134759.1
ENSMUSG00000052752.15 ENSMUST00000176353.7 ENSMUSP00000135267.1
ENSMUSG00000052752.15 ENSMUST00000176668.7 ENSMUSP00000135586.1
ENSMUSG00000052752.15 ENSMUST00000176086.7 ENSMUSP00000135845.1
ENSMUSG00000052752.15 ENSMUST00000175698.7 ENSMUSP00000135456.1
ENSMUSG00000052752.15 ENSMUST00000177502.7 ENSMUSP00000134970.1
ENSMUSG00000052752.15 ENSMUST00000176237.7 ENSMUSP00000134946.1
ENSMUSG00000052752.15 ENSMUST00000177154.7 ENSMUSP00000135874.1
ENSMUSG00000052752.15 ENSMUST00000177401.7 ENSMUSP00000135341.1
ENSMUSG00000052752.15 ENSMUST00000176178.7 ENSMUSP00000134808.1
ENSMUSG00000052752.15 ENSMUST00000177405.7 ENSMUSP00000135127.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
iRefIndex
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.10e-31 106.2 393 424
UBD/Beta-Prp 3.40e-48 165.5 393 669
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v+cl+  s  +ll sGs D+tikvWD+
   Q: 393  GHQGPVWCLCVySMgDLLFSGSSDKTIKVWDT 424
           8*********778889***************6 PP
   

   UBD/Beta-Prp
   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdv.ttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           gh+  ++ c+++   ++ll++gs d+tikvwd+ tt k+ ++l+gh++ v a++++     l +gs D ti vwd+++ + v t+++h+
   Q: 393  GHQG-PVWCLCVYSMGDLLFSGSSDKTIKVWDTcTTYKCQKTLEGHDGIVLALCIQGC--KLYSGSADCTIIVWDIQNLQKVNTIRAHD 478
           5555.55569999*******************846678899***************99..6**************************** PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdl.etgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           + v++l +s   + l sGs  + i+vwd+  t+ +l++ l+g +++v+ +v  +  ++l sGs+ +t+++Wd++t ++++ l+    +s
   Q: 479  NPVCTLVSSH--NMLFSGS-LKAIKVWDIvGTELKLKKELTGLNHWVRALVAAQ--SYLYSGSY-QTIKIWDIRTLDCIHVLQT-SGGS 560
           *****99999..9******.9*******7368888888**************99..*******9.79***************99.**** PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs..pnderlvsgssDgsiriWdlrsgdllktlqlhnssvis 269
           vys++++    ++v g + + + +wd++++e vrtl+gh  +v+ +++   p+++ + s+s D+s+r+W +++  +++tl +h+ sv++
   Q: 561  VYSIAVTN--HHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVIstPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTA 647
           *******9..8***********************************99888************************************** PP
   S: 270  vavlsfgdnvlvlgsedskvniwkl 294
            av   ++  l++g+ ds+v++w +
   Q: 648  LAV---SRGRLFSGAVDSTVKVWTC 669
           **9...*****************86 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MSSAKSARYD RFSGGPANLP SSDSSGTRME TTFGPTFSTV TTITKADGTG TYKQHRRTPS 60
SSSTLAYSPR DEEDGMPPIN TPRRSDSAIS VRSLHSESSM SLRSTFSLPE EEEEPEPLVF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063844|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAAGCTCAA AGCGTGAAGC AGCACCTAGA GTTCCTGAAG TCCGTGAACT ACAAGTTCCG 60
ACCTGCCCCG GGACTTCCGG CTCCTGTATC CTGAAACCTT TCCCGGCCGC GGGCCGAGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063844|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR001370--BIR_rpt
IPR020472--G-protein_beta_WD-40_rep
IPR008974--TRAF-like
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF
Pfam

PF00400--WD40
PF13445--zf-RING_UBOX
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00184--RING
SM00320--WD40
Gene Ontology

GO:0043231--C:intracellular membrane-bounded organelle
GO:0005886--C:plasma membrane
GO:0000151--C:ubiquitin ligase complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0000185--P:activation of MAPKKK activity
GO:0006915--P:apoptotic process
GO:2001235--P:positive regulation of apoptotic signaling pathway
KEGG mmu:224619
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001971 Ailuropoda melanoleuca 95.99 0.00e+00 1243.00
IUUC-Apl-004098 Anas platyrhynchos 95.01 0.00e+00 1201.00
IUUC-Aca-004852 Anolis carolinensis 87.99 0.00e+00 969.00
IUUC-Ame-011275 Astyanax mexicanus 82.94 0.00e+00 935.00
IUUC-Bta-013153 Bos taurus 96.86 0.00e+00 1267.00
IUUC-Cja-019243 Callithrix jacchus 95.72 0.00e+00 1218.00
IUUC-Cfa-020036 Canis familiaris 97.31 0.00e+00 1274.00
IUUC-Cpo-022194 Cavia porcellus 97.30 0.00e+00 1267.00
IUUC-Csa-023363 Chlorocebus sabaeus 97.16 0.00e+00 1273.00
IUUC-Cin-025279 Ciona intestinalis 58.92 0.00e+00 801.00
IUUC-Csv-026163 Ciona savignyi 64.73 0.00e+00 772.00
IUUC-Dre-027998 Danio rerio 90.64 0.00e+00 1114.00
IUUC-Dno-029356 Dasypus novemcinctus 95.98 2.00e-130 457.00
IUUC-Dor-030750 Dipodomys ordii 95.37 0.00e+00 1228.00
IUUC-Eca-033671 Equus caballus 81.45 0.00e+00 978.00
IUUC-Eeu-034765 Erinaceus europaeus 97.70 5.00e-166 577.00
IUUC-Fca-035843 Felis catus 97.31 0.00e+00 1277.00
IUUC-Fal-037237 Ficedula albicollis 93.28 0.00e+00 1235.00
IUUC-Gmo-038779 Gadus morhua 81.83 0.00e+00 1010.00
IUUC-Gga-040579 Gallus gallus 92.84 0.00e+00 1226.00
IUUC-Gac-042233 Gasterosteus aculeatus 86.13 0.00e+00 1121.00
IUUC-Gma-042711 Glycine max 26.81 3.00e-19 89.40
IUUC-Ggo-045147 Gorilla gorilla 96.57 0.00e+00 1265.00
IUUC-Hsa-046117 Homo sapiens 96.57 0.00e+00 1267.00
IUUC-Itr-048899 Ictidomys tridecemlineatus 97.46 0.00e+00 1274.00
IUUC-Lch-050593 Latimeria chalumnae 90.76 0.00e+00 1181.00
IUUC-Loc-052444 Lepisosteus oculatus 90.22 0.00e+00 1217.00
IUUC-Laf-053499 Loxodonta africana 90.67 0.00e+00 1172.00
IUUC-Mcc-055038 Macaca mulatta 97.01 0.00e+00 1270.00
IUUC-Meu-056610 Macropus eugenii 94.81 0.00e+00 941.00
IUUC-Mtr-057641 Medicago truncatula 27.73 3.00e-19 89.70
IUUC-Mga-060183 Meleagris gallopavo 92.41 0.00e+00 1219.00
IUUC-Mmr-061133 Microcebus murinus 95.22 0.00e+00 1196.00
IUUC-Mdo-062312 Monodelphis domestica 95.83 0.00e+00 1259.00
IUUC-Mpu-066552 Mustela putorius furo 96.72 0.00e+00 1240.00
IUUC-Mlu-067719 Myotis lucifugus 96.87 0.00e+00 1239.00
IUUC-Nle-070045 Nomascus leucogenys 97.60 0.00e+00 1192.00
IUUC-Opr-070927 Ochotona princeps 94.33 0.00e+00 1215.00
IUUC-Ont-072680 Oreochromis niloticus 85.59 0.00e+00 1140.00
IUUC-Oan-073521 Ornithorhynchus anatinus 94.00 2.00e-52 196.00
IUUC-Ogu-077987 Oryza glumaepatula 25.86 4.00e-19 89.40
IUUC-Oru-085210 Oryza rufipogon 25.60 2.00e-19 90.10
IUUC-Ola-087454 Oryzias latipes 89.47 0.00e+00 1185.00
IUUC-Oga-088380 Otolemur garnettii 96.72 0.00e+00 1268.00
IUUC-Oar-089558 Ovis aries 79.59 0.00e+00 1004.00
IUUC-Ptr-091606 Pan troglodytes 96.57 0.00e+00 1265.00
IUUC-Pan-092227 Papio anubis 97.01 0.00e+00 1270.00
IUUC-Psi-093853 Pelodiscus sinensis 86.62 0.00e+00 1020.00
IUUC-Pma-094541 Petromyzon marinus 82.28 1.00e-156 545.00
IUUC-Pfo-096237 Poecilia formosa 85.69 0.00e+00 1137.00
IUUC-Pab-097589 Pongo abelii 96.72 0.00e+00 1267.00
IUUC-Pca-100375 Procavia capensis 93.68 0.00e+00 1182.00
IUUC-Pva-102434 Pteropus vampyrus 97.31 0.00e+00 1273.00
IUUC-Rno-105443 Rattus norvegicus 99.40 0.00e+00 1272.00
IUUC-Sha-106517 Sarcophilus harrisii 95.54 0.00e+00 1254.00
IUUC-Ssc-115990 Sus scrofa 96.12 0.00e+00 1258.00
IUUC-Tgu-117222 Taeniopygia guttata 92.95 0.00e+00 1222.00
IUUC-Tru-118392 Takifugu rubripes 89.04 0.00e+00 1145.00
IUUC-Tni-120220 Tetraodon nigroviridis 88.50 0.00e+00 1135.00
IUUC-Tca-121793 Theobroma cacao 27.11 1.00e-20 94.40
IUUC-Tur-126339 Triticum urartu 26.69 2.00e-17 84.00
IUUC-Tbe-128045 Tupaia belangeri 99.31 2.00e-161 562.00
IUUC-Ttr-128203 Tursiops truncatus 93.58 0.00e+00 1207.00
IUUC-Xtr-132043 Xenopus tropicalis 91.64 0.00e+00 1241.00
Created Date 25-Jun-2017

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