iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003211

Ensembl Protein ID

ENSAPLP00000007648.1

UniProt Accession

U3IK76; U3IK76_ANAPL

Genbank Protein ID

ENSAPLP00000007648

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01035503

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000007958.1	ENSAPLT00000008312.1	ENSAPLP00000007648.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.80e-16	58.5	401	456

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q+ deL++k+G+ +  i  ee ++gW+kg + l+g  Gl P+n+vek+
   Q: 401  RVRALYDYTGQEADELSFKAGEELMKI-SEEDEQGWCKG-RLLTGHVGLYPANYVEKV 456
           589*********************999.999********.5***************98 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MSSEDDAGGE APGGSFWEAG NYRRTVKRVD DGYRLCNDLI SCFQERAKIE KNYAQQLTEW 60
SRKWRTNVEK GPQYGTLEKA WHAFLTAADR LSEIHLDVRN HLAGEDSDKI KAWQKEAYHK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTCTCCTCA GCTTAACTGA AATCTGCAAA AATTCCTTGC TGCAAGAAAA CGAGGGCGAT 60
GTCATCAGAA GATGATGCTG GCGGGGAGGC TCCTGGGGGC AGTTTCTGGG AGGTAAGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	61.62	5.00e-177	613.00
IUUC-Aca-004256	Anolis carolinensis	84.31	0.00e+00	806.00
IUUC-Ame-011049	Astyanax mexicanus	64.72	5.00e-165	573.00
IUUC-Bta-013322	Bos taurus	65.16	1.00e-172	598.00
IUUC-Cja-018907	Callithrix jacchus	64.19	5.00e-179	620.00
IUUC-Cfa-021126	Canis familiaris	64.63	4.00e-178	617.00
IUUC-Cpo-021491	Cavia porcellus	63.97	1.00e-177	615.00
IUUC-Csa-023107	Chlorocebus sabaeus	64.85	7.00e-180	622.00
IUUC-Cne-026895	Cryptococcus neoformans	42.62	3.00e-09	55.50
IUUC-Dre-027933	Danio rerio	63.76	1.00e-164	572.00
IUUC-Dno-029002	Dasypus novemcinctus	65.28	3.00e-172	597.00
IUUC-Eca-033824	Equus caballus	64.63	5.00e-180	623.00
IUUC-Eeu-035122	Erinaceus europaeus	67.67	9.00e-112	396.00
IUUC-Fca-036420	Felis catus	65.94	0.00e+00	629.00
IUUC-Fal-037277	Ficedula albicollis	95.42	0.00e+00	911.00
IUUC-Gga-040941	Gallus gallus	97.16	0.00e+00	930.00
IUUC-Gac-041374	Gasterosteus aculeatus	59.74	1.00e-144	506.00
IUUC-Ggo-045211	Gorilla gorilla	64.63	3.00e-179	620.00
IUUC-Hsa-046053	Homo sapiens	64.85	7.00e-180	622.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	65.07	2.00e-179	621.00
IUUC-Loc-052808	Lepisosteus oculatus	69.65	0.00e+00	639.00
IUUC-Laf-054211	Loxodonta africana	64.19	9.00e-170	588.00
IUUC-Mcc-055044	Macaca mulatta	64.85	7.00e-180	622.00
IUUC-Mga-059216	Meleagris gallopavo	97.17	0.00e+00	931.00
IUUC-Mmr-061172	Microcebus murinus	64.41	3.00e-180	624.00
IUUC-Mdo-062600	Monodelphis domestica	64.63	0.00e+00	630.00
IUUC-Mmu-063218	Mus musculus	64.41	2.00e-178	618.00
IUUC-Mpu-066819	Mustela putorius furo	59.02	2.00e-175	607.00
IUUC-Mlu-067597	Myotis lucifugus	63.97	8.00e-177	612.00
IUUC-Nle-069195	Nomascus leucogenys	64.41	2.00e-178	618.00
IUUC-Opr-071050	Ochotona princeps	66.16	8.00e-176	609.00
IUUC-Ont-071612	Oreochromis niloticus	60.50	1.00e-155	542.00
IUUC-Oan-073256	Ornithorhynchus anatinus	65.07	9.00e-178	615.00
IUUC-Ocu-074653	Oryctolagus cuniculus	65.72	1.00e-175	608.00
IUUC-Oga-089040	Otolemur garnettii	63.76	1.00e-178	619.00
IUUC-Oar-089918	Ovis aries	64.19	2.00e-174	604.00
IUUC-Ptr-091307	Pan troglodytes	64.85	7.00e-180	622.00
IUUC-Pan-092512	Papio anubis	64.85	7.00e-180	622.00
IUUC-Pfo-096881	Poecilia formosa	60.73	9.00e-157	546.00
IUUC-Pab-098620	Pongo abelii	64.85	7.00e-180	622.00
IUUC-Pva-102464	Pteropus vampyrus	62.01	4.00e-169	587.00
IUUC-Rno-106091	Rattus norvegicus	64.19	1.00e-176	612.00
IUUC-Sha-107474	Sarcophilus harrisii	66.38	0.00e+00	641.00
IUUC-Ssc-116128	Sus scrofa	64.41	5.00e-178	616.00
IUUC-Tgu-117511	Taeniopygia guttata	88.00	0.00e+00	850.00
IUUC-Tru-118005	Takifugu rubripes	63.68	9.00e-154	536.00
IUUC-Tni-119851	Tetraodon nigroviridis	62.44	1.00e-144	505.00
IUUC-Ttr-129313	Tursiops truncatus	65.94	0.00e+00	627.00
IUUC-Vpa-130760	Vicugna pacos	73.22	5.00e-82	297.00
IUUC-Xtr-132697	Xenopus tropicalis	61.32	7.00e-157	546.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence