iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041328

Ensembl Protein ID

ENSGACP00000010145.2

UniProt Accession

G3NXS5; G3NXS5_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000007609.2	ENSGACT00000010167.2	ENSGACP00000010145.2
ENSGACG00000007609.2	ENSGACT00000010156.1	ENSGACP00000010134.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-26	91.1	1315	1349
UBD/Beta-Prp	1.90e-42	145.8	1310	1551

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gH+  v c++ +d ll +Gs D t+k+W+l tg  
   Q: 1315 GHSKAVLCVDATDELLFTGSKDRTCKMWNLVTGQE 1349
           8999*****9878*****************99965 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdlet.gqcle 130
           ++  +gh+++v +v+  ++  +l tgs+Drt k w+l tg+ ++tlkgh ++v+s++++p ++ lv   + ++i+vwd++   +c++
   Q: 1310 VSVAEGHSKAVLCVDATDE--LLFTGSKDRTCKMWNLVTGQEIVTLKGHPNNVVSVKYCP-SSCLVFSVSTSYIKVWDIRDsAKCVR 1393
           555699*********9999..9**************************************.67777777799*******96157777 PP
   S: 131  e.....................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsng. 192
           +                     t+++ +  +n ++++p+g++l ++ + +tvr+Wdl+++  + +l g h +sv +l+         
   Q: 1394 TltssgqvvpgdvcagattrtiTFAQGECQINQIALNPSGSVLYAA-AGNTVRMWDLNRMHGMGKLIG-HIGSVMCLTvglS---Ll 1475
           7*********************99999***********98544443.4579****************9.*********6651...33 PP
   S: 193  ..kelvsgsldgtvklwdlqtgecvrtlnght......dnvksvrfspnderlvsgssDgsiriWdlrsgdllktlql 262
              ++++gs+d +vk++d+ +g + ++  +h+      d + +++++  ++ l sgs D+ i+ Wdl++++l++++ +
   Q: 1476 gkDQVITGSKDHYVKVFDVAEGMVGNIGPAHNfepphyDGIECLAVH--GDVLFSGSRDNGIKKWDLQHQELTQQIPN 1551
           4478********************99999999999999*********..***********************998765 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

RIRPQMAKEK IEGCHVCTLV TPGEPQVLLG KDKAFTYDFV LDIDSEQQHI YQACVYNLIE 60
GCFEGYNATV FAYGQTGSGK TYTMGTGFDM SLGQHEQGII PRAVHQLFDG IKNNRARAQE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGATTCGTC CTCAGATGGC CAAGGAGAAG ATAGAGGGCT GTCATGTATG CACGCTCGTC 60
ACACCCGGAG AACCACAAGT CCTTCTGGGT AAAGACAAAG CTTTCACTTA TGACTTTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	72.21	0.00e+00	2160.00
IUUC-Apl-003204	Anas platyrhynchos	74.08	0.00e+00	741.00
IUUC-Aca-004506	Anolis carolinensis	72.16	0.00e+00	1399.00
IUUC-Ame-011515	Astyanax mexicanus	78.19	0.00e+00	2477.00
IUUC-Bta-013185	Bos taurus	63.13	0.00e+00	1113.00
IUUC-Cja-018844	Callithrix jacchus	70.85	0.00e+00	2162.00
IUUC-Cfa-021187	Canis familiaris	73.21	0.00e+00	2227.00
IUUC-Cpo-022444	Cavia porcellus	72.25	0.00e+00	2195.00
IUUC-Csa-023852	Chlorocebus sabaeus	72.47	0.00e+00	2216.00
IUUC-Dre-027839	Danio rerio	76.12	0.00e+00	2407.00
IUUC-Dno-030058	Dasypus novemcinctus	72.17	0.00e+00	2161.00
IUUC-Dor-030673	Dipodomys ordii	70.36	0.00e+00	2066.00
IUUC-Ete-032705	Echinops telfairi	64.87	0.00e+00	695.00
IUUC-Eca-033885	Equus caballus	71.80	0.00e+00	2165.00
IUUC-Eeu-035338	Erinaceus europaeus	71.74	0.00e+00	931.00
IUUC-Fca-035388	Felis catus	72.29	0.00e+00	2064.00
IUUC-Fal-037044	Ficedula albicollis	72.79	0.00e+00	2259.00
IUUC-Gmo-039034	Gadus morhua	75.92	0.00e+00	2286.00
IUUC-Ggo-045392	Gorilla gorilla	72.00	0.00e+00	2197.00
IUUC-Hsa-046713	Homo sapiens	72.41	0.00e+00	2216.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	73.39	0.00e+00	1281.00
IUUC-Loc-052703	Lepisosteus oculatus	79.92	0.00e+00	2531.00
IUUC-Laf-054193	Loxodonta africana	68.05	0.00e+00	1259.00
IUUC-Mcc-055484	Macaca mulatta	71.49	0.00e+00	2201.00
IUUC-Meu-056278	Macropus eugenii	71.75	0.00e+00	1000.00
IUUC-Mga-059816	Meleagris gallopavo	71.15	0.00e+00	2185.00
IUUC-Mmr-061071	Microcebus murinus	72.15	0.00e+00	2197.00
IUUC-Mdo-062845	Monodelphis domestica	73.44	0.00e+00	2265.00
IUUC-Mmu-063967	Mus musculus	72.31	0.00e+00	2185.00
IUUC-Mpu-066448	Mustela putorius furo	72.11	0.00e+00	2205.00
IUUC-Nle-070037	Nomascus leucogenys	74.15	0.00e+00	1422.00
IUUC-Opr-070325	Ochotona princeps	68.69	0.00e+00	2054.00
IUUC-Ont-071851	Oreochromis niloticus	88.56	0.00e+00	2823.00
IUUC-Oan-073615	Ornithorhynchus anatinus	72.70	0.00e+00	2086.00
IUUC-Ocu-073855	Oryctolagus cuniculus	72.78	0.00e+00	2194.00
IUUC-Ola-086703	Oryzias latipes	86.91	0.00e+00	2764.00
IUUC-Oga-088171	Otolemur garnettii	72.10	0.00e+00	2138.00
IUUC-Ptr-090535	Pan troglodytes	72.60	0.00e+00	1391.00
IUUC-Pan-091917	Papio anubis	71.62	0.00e+00	2012.00
IUUC-Psi-093752	Pelodiscus sinensis	68.51	0.00e+00	1198.00
IUUC-Pfo-096827	Poecilia formosa	81.02	0.00e+00	2564.00
IUUC-Pab-098441	Pongo abelii	72.41	0.00e+00	2219.00
IUUC-Pca-100781	Procavia capensis	78.37	0.00e+00	750.00
IUUC-Pva-103099	Pteropus vampyrus	70.78	0.00e+00	1017.00
IUUC-Rno-105872	Rattus norvegicus	72.23	0.00e+00	2206.00
IUUC-Sha-107097	Sarcophilus harrisii	72.34	0.00e+00	2160.00
IUUC-Ssc-115638	Sus scrofa	71.72	0.00e+00	1912.00
IUUC-Tgu-116504	Taeniopygia guttata	74.36	0.00e+00	825.00
IUUC-Tru-118242	Takifugu rubripes	87.49	0.00e+00	2865.00
IUUC-Tni-119976	Tetraodon nigroviridis	91.31	0.00e+00	1146.00
IUUC-Ttr-128824	Tursiops truncatus	67.76	0.00e+00	2006.00
IUUC-Xtr-131798	Xenopus tropicalis	59.18	0.00e+00	1757.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence