iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000005921.3	ENSMMUT00000075120.1	ENSMMUP00000042578.1
ENSMMUG00000005921.3	ENSMMUT00000069172.1	ENSMMUP00000046501.1
ENSMMUG00000005921.3	ENSMMUT00000024488.3	ENSMMUP00000022921.3
ENSMMUG00000005921.3	ENSMMUT00000008286.3	ENSMMUP00000007788.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-31	107.1	1539	1573
UBD/Beta-Prp	3.20e-53	182.0	1406	1609

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           H+d+v++laf ++ ++l+s+++ g+ikvW+++ ++
   Q: 1539 HKDWVCALAFiPGrPMLLSACRAGVIKVWNVDNFT 1573
           ***********999****************98765 PP

UBD/Beta-Prp

   S: 51   heaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqclee... 131
            e +++++ +sp+g +++ +++ +++++w+ls +++v +l+gh   v++l++ +   + d +v+Gs+d ++++++l  g+c+     
   Q: 1406 GEHQINQIALSPSG-TMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQtasQHDLVVTGSKDHYVKMFEL--GECVTGtig 1489
           5667999******9.9999999***************************99999985559**************55..667765779 PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
               ++ +h + + c+++++  ++l+sGs D+ ++ Wdl +++l+++   +h+d v  l+f + ++ l+s+ + g +k+w++ + + 
   Q: 1490 pthnFEPPHYDGIECLAIQG--DILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTP 1574
           99999999**********99..9*************************989************************************ PP
   S: 215  vrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
           + + +gh+++++ + +    +++ ++ssD  +++W++
   Q: 1575 IGEIKGHDSPINAICTN--AKHIFTASSDCRVKLWNY 1609
           ************77777..9***************96 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

GWLDGDSCVN GCLLTQIRPQ LSKEKIEGCH ICTSVTPGEP QVLLGKDKAF TYDFVFDLDT 60
WQEQIYSTCV SKLIEGCFEG YNATVLAYGQ TGAGKTYTMG TGFDMATSEE EQGIIPRAIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCCGCCAG CCGCGCCCGC GCCCCCGCCT CCCGCAGCCG CAGCCGCTGC CTTGGGCATT 60
GGCCCCCAGA CCCCCGCCTC TGATCCACGC CCAGACCCTA GAGCCAGAGG GCCATGGCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001279	Ailuropoda melanoleuca	95.78	0.00e+00	2813.00
IUUC-Apl-003204	Anas platyrhynchos	76.40	0.00e+00	1584.00
IUUC-Aca-004506	Anolis carolinensis	80.96	0.00e+00	1635.00
IUUC-Ame-011515	Astyanax mexicanus	74.36	0.00e+00	1452.00
IUUC-Bta-013185	Bos taurus	74.90	0.00e+00	1442.00
IUUC-Cja-018844	Callithrix jacchus	94.17	0.00e+00	2831.00
IUUC-Cfa-021187	Canis familiaris	96.27	0.00e+00	2854.00
IUUC-Cpo-022444	Cavia porcellus	93.53	0.00e+00	2837.00
IUUC-Csa-023852	Chlorocebus sabaeus	98.29	0.00e+00	2926.00
IUUC-Dre-027839	Danio rerio	73.89	0.00e+00	1439.00
IUUC-Dno-030058	Dasypus novemcinctus	91.92	0.00e+00	2761.00
IUUC-Dor-030673	Dipodomys ordii	91.25	0.00e+00	2655.00
IUUC-Ete-032705	Echinops telfairi	82.29	0.00e+00	889.00
IUUC-Eca-033885	Equus caballus	95.37	0.00e+00	2801.00
IUUC-Eeu-035338	Erinaceus europaeus	81.89	0.00e+00	2199.00
IUUC-Fca-035388	Felis catus	96.88	0.00e+00	2695.00
IUUC-Fal-037044	Ficedula albicollis	86.65	0.00e+00	2696.00
IUUC-Gmo-039034	Gadus morhua	77.10	0.00e+00	756.00
IUUC-Gac-041328	Gasterosteus aculeatus	71.94	0.00e+00	2277.00
IUUC-Ggo-045392	Gorilla gorilla	97.50	0.00e+00	2901.00
IUUC-Hsa-046713	Homo sapiens	97.98	0.00e+00	2913.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	95.95	0.00e+00	1684.00
IUUC-Loc-052703	Lepisosteus oculatus	78.54	0.00e+00	2473.00
IUUC-Laf-054193	Loxodonta africana	85.96	0.00e+00	2487.00
IUUC-Meu-056278	Macropus eugenii	87.48	0.00e+00	1192.00
IUUC-Mga-059816	Meleagris gallopavo	84.17	0.00e+00	2586.00
IUUC-Mmr-061071	Microcebus murinus	92.72	0.00e+00	2780.00
IUUC-Mdo-062845	Monodelphis domestica	89.91	0.00e+00	2761.00
IUUC-Mmu-063967	Mus musculus	94.62	0.00e+00	2790.00
IUUC-Mpu-066448	Mustela putorius furo	96.07	0.00e+00	2863.00
IUUC-Nle-070037	Nomascus leucogenys	96.33	0.00e+00	2237.00
IUUC-Opr-070325	Ochotona princeps	92.04	0.00e+00	2664.00
IUUC-Ont-071851	Oreochromis niloticus	72.00	0.00e+00	2293.00
IUUC-Oan-073615	Ornithorhynchus anatinus	88.02	0.00e+00	2542.00
IUUC-Ocu-073855	Oryctolagus cuniculus	95.35	0.00e+00	2814.00
IUUC-Ola-086703	Oryzias latipes	71.33	0.00e+00	2273.00
IUUC-Oga-088171	Otolemur garnettii	94.32	0.00e+00	2810.00
IUUC-Oar-089693	Ovis aries	77.00	0.00e+00	1231.00
IUUC-Ptr-090535	Pan troglodytes	98.70	0.00e+00	1852.00
IUUC-Pan-091917	Papio anubis	98.37	0.00e+00	2706.00
IUUC-Psi-093752	Pelodiscus sinensis	76.96	0.00e+00	1396.00
IUUC-Pfo-096827	Poecilia formosa	68.68	0.00e+00	1351.00
IUUC-Pab-098441	Pongo abelii	97.98	0.00e+00	2925.00
IUUC-Pca-100781	Procavia capensis	95.58	0.00e+00	908.00
IUUC-Pva-103099	Pteropus vampyrus	89.70	0.00e+00	1347.00
IUUC-Rno-105872	Rattus norvegicus	93.77	0.00e+00	2835.00
IUUC-Sha-107097	Sarcophilus harrisii	89.14	0.00e+00	2652.00
IUUC-Ssc-115638	Sus scrofa	93.81	0.00e+00	2460.00
IUUC-Tgu-116504	Taeniopygia guttata	87.40	0.00e+00	1699.00
IUUC-Tru-118242	Takifugu rubripes	72.55	0.00e+00	1482.00
IUUC-Ttr-128824	Tursiops truncatus	88.99	0.00e+00	2259.00
IUUC-Xtr-131798	Xenopus tropicalis	64.63	0.00e+00	1177.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence