iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054053

Ensembl Protein ID

ENSLAFP00000015240.3

UniProt Accession

G3TKA4; G3TKA4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

STRAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000018184.3	ENSLAFT00000018187.3	ENSLAFP00000015240.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-27	93.7	263	294
UBD/Beta-Prp	2.60e-40	138.8	12	294

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtll.vsGsdDgtikvWDl 30
           gH ++++c++f +d+ l +sGs Dgt+++W +
   Q: 263  GHFGPIHCVRFsPDGELyASGSEDGTLRLWQT 294
           799*********997776************85 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkf...spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkg 92
           gh   ++ +++f   +p + +l+++++dg+  + + +tg+ + ++ gh+++v+  ++++d+   +t++ D t+kvwd  +g+ ++tl  
   Q: 12   GHTR-PVVDLAFsgiTPYGYFLISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWDAVSGDELMTLA- 98
           4444.5555888888899999*******************************************************************. PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           h++ v +++f +++++l++G++d+ +r++dl++ +   +  sgh++ +  v + ++++ + s ++D+tvrlWd +t++ ++ l    + 
   Q: 99   HKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHNSGIKKVLWCSEDKQILS-ADDKTVRLWDQATMTEVKSLN--FNM 184
           **************************************9***************98877766.69******************5..699 PP
   S: 182  svyslsfdsng........................................kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrf 230
           sv s+++ ++g                                        ++lv+g++d ++  +d+ +ge +++++gh  ++ +vrf
   Q: 185  SVSSMEYIPEGeilvitygrtiafhsavsldpiksfeapatinsaslhpekEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRF 273
           9*****888888888888888888888888888888888888888888888************************************** PP
   S: 231  spnderlvsgssDgsiriWdl 251
           sp++e+++sgs+Dg++r+W +
   Q: 274  SPDGELYASGSEDGTLRLWQT 294
           *******************65 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MALRQTPLTC SGHTRPVVDL AFSGITPYGY FLISACKDGK PMLRQGDTGD WIGTFLGHKG 60
AVWGATLNKD ATKAATAAAD FTAKVWDAVS GDELMTLAHK HIVKTVDFTQ DSNYLLTGGQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCATTGA GGCAGACACC GCTCACCTGC TCGGGCCACA CGCGACCGGT GGTTGATTTG 60
GCCTTCAGCG GCATCACGCC TTATGGCTAT TTCTTAATCA GCGCTTGCAA AGGTGAGCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0032797--C:SMN complex
GO:0034719--C:SMN-Sm protein complex
GO:0003723--F:RNA binding
GO:0030277--P:maintenance of gastrointestinal epithelium
GO:0010633--P:negative regulation of epithelial cell migration
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0060394--P:negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0000387--P:spliceosomal snRNP assembly

KEGG

lav:100654665

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000668	Aegilops tauschii	50.17	1.00e-76	279.00
IUUC-Aml-002091	Ailuropoda melanoleuca	94.51	0.00e+00	642.00
IUUC-Atr-002571	Amborella trichopoda	52.23	8.00e-80	290.00
IUUC-Apl-003327	Anas platyrhynchos	86.39	9.00e-148	515.00
IUUC-Aca-005324	Anolis carolinensis	87.14	1.00e-167	582.00
IUUC-Aly-006452	Arabidopsis lyrata	50.00	8.00e-78	283.00
IUUC-Ath-006646	Arabidopsis thaliana	50.00	7.00e-78	283.00
IUUC-Acl-008014	Aspergillus clavatus	40.42	7.00e-49	187.00
IUUC-Afl-008701	Aspergillus flavus	39.72	1.00e-33	137.00
IUUC-Afu-008942	Aspergillus fumigatus	31.12	2.00e-35	142.00
IUUC-Ani-009394	Aspergillus nidulans	41.14	2.00e-49	189.00
IUUC-Ang-009593	Aspergillus niger	37.84	1.00e-35	144.00
IUUC-Aor-010206	Aspergillus oryzae	42.34	8.00e-50	190.00
IUUC-Ame-011328	Astyanax mexicanus	82.75	1.00e-144	505.00
IUUC-Bgr-012308	Blumeria graminis	40.00	1.00e-56	213.00
IUUC-Bta-013429	Bos taurus	97.43	0.00e+00	644.00
IUUC-Bci-013803	Botrytis cinerea	40.35	5.00e-55	207.00
IUUC-Bdi-014996	Brachypodium distachyon	49.30	1.00e-76	280.00
IUUC-Bol-016595	Brassica oleracea	50.34	5.00e-80	290.00
IUUC-Bra-017775	Brassica rapa	49.49	4.00e-79	289.00
IUUC-Cja-018740	Callithrix jacchus	92.29	0.00e+00	625.00
IUUC-Cfa-021145	Canis familiaris	98.00	0.00e+00	646.00
IUUC-Cpo-022373	Cavia porcellus	97.14	0.00e+00	644.00
IUUC-Cre-022806	Chlamydomonas reinhardtii	44.52	4.00e-61	228.00
IUUC-Csa-023098	Chlorocebus sabaeus	96.29	0.00e+00	635.00
IUUC-Cho-024856	Choloepus hoffmanni	88.57	2.00e-161	561.00
IUUC-Cin-025541	Ciona intestinalis	58.06	2.00e-103	368.00
IUUC-Csv-026287	Ciona savignyi	58.13	4.00e-94	337.00
IUUC-Cgl-026513	Colletotrichum gloeosporioides	40.18	2.00e-53	202.00
IUUC-Cne-026869	Cryptococcus neoformans	46.20	4.00e-70	258.00
IUUC-Dre-028457	Danio rerio	76.35	7.00e-149	519.00
IUUC-Dno-029213	Dasypus novemcinctus	96.57	0.00e+00	645.00
IUUC-Dse-031350	Dothistroma septosporum	39.29	1.00e-49	190.00
IUUC-Dme-031857	Drosophila melanogaster	60.06	1.00e-106	379.00
IUUC-Ete-032558	Echinops telfairi	87.60	7.00e-121	426.00
IUUC-Eca-033934	Equus caballus	97.71	0.00e+00	645.00
IUUC-Eeu-034650	Erinaceus europaeus	82.86	5.00e-163	566.00
IUUC-Fca-035909	Felis catus	98.00	0.00e+00	647.00
IUUC-Fal-036706	Ficedula albicollis	86.94	1.00e-143	502.00
IUUC-Fox-037780	Fusarium oxysporum	40.77	5.00e-52	197.00
IUUC-Fso-038197	Fusarium solani	41.19	4.00e-54	204.00
IUUC-Gmo-039707	Gadus morhua	77.35	3.00e-133	467.00
IUUC-Ggr-040054	Gaeumannomyces graminis	39.40	2.00e-54	205.00
IUUC-Gga-040901	Gallus gallus	88.29	9.00e-174	602.00
IUUC-Gac-041876	Gasterosteus aculeatus	74.00	1.00e-142	498.00
IUUC-Gma-043984	Glycine max	51.55	9.00e-80	290.00
IUUC-Ggo-044583	Gorilla gorilla	90.03	3.00e-169	587.00
IUUC-Hsa-046553	Homo sapiens	93.11	0.00e+00	634.00
IUUC-Hvu-047544	Hordeum vulgare	50.69	1.00e-78	286.00
IUUC-Itr-047980	Ictidomys tridecemlineatus	98.29	0.00e+00	654.00
IUUC-Lch-050078	Latimeria chalumnae	82.05	3.00e-157	547.00
IUUC-Lpe-051246	Leersia perrieri	50.86	2.00e-79	288.00
IUUC-Loc-052598	Lepisosteus oculatus	77.78	2.00e-151	528.00
IUUC-Lma-053226	Leptosphaeria maculans	44.59	3.00e-56	211.00
IUUC-Mcc-054652	Macaca mulatta	92.86	0.00e+00	632.00
IUUC-Mor-057256	Magnaporthe oryzae	38.58	5.00e-52	197.00
IUUC-Mpo-057303	Magnaporthe poae	39.76	7.00e-55	207.00
IUUC-Mtr-058421	Medicago truncatula	51.55	1.00e-79	290.00
IUUC-Mla-059073	Melampsora laricipopulina	45.43	1.00e-64	239.00
IUUC-Mga-059664	Meleagris gallopavo	88.03	2.00e-172	597.00
IUUC-Mvi-060534	Microbotryum violaceum	35.09	7.00e-41	160.00
IUUC-Mmr-061044	Microcebus murinus	97.52	5.00e-179	619.00
IUUC-Mdo-063019	Monodelphis domestica	95.14	0.00e+00	636.00
IUUC-Mmu-064092	Mus musculus	97.14	0.00e+00	641.00
IUUC-Mac-065143	Musa acuminata	52.07	1.00e-78	286.00
IUUC-Mpu-066557	Mustela putorius furo	98.29	0.00e+00	654.00
IUUC-Mlu-068179	Myotis lucifugus	96.57	0.00e+00	643.00
IUUC-Nfi-068553	Neosartorya fischeri	40.42	2.00e-48	186.00
IUUC-Ncr-068934	Neurospora crassa	38.82	4.00e-49	188.00
IUUC-Nle-069482	Nomascus leucogenys	92.84	0.00e+00	630.00
IUUC-Opr-071055	Ochotona princeps	76.29	5.00e-132	463.00
IUUC-Ont-072663	Oreochromis niloticus	73.70	4.00e-139	487.00
IUUC-Ocu-074942	Oryctolagus cuniculus	97.71	0.00e+00	645.00
IUUC-Oba-075160	Oryza barthii	50.86	2.00e-79	288.00
IUUC-Obr-076864	Oryza brachyantha	50.86	3.00e-79	288.00
IUUC-Ogl-077076	Oryza glaberrima	50.86	3.00e-79	288.00
IUUC-Ogu-078591	Oryza glumaepatula	50.86	2.00e-79	288.00
IUUC-Oin-079631	Oryza indica	49.66	1.00e-77	283.00
IUUC-Olo-080389	Oryza longistaminata	44.60	3.00e-51	194.00
IUUC-Ome-081693	Oryza meridionalis	49.31	2.00e-76	279.00
IUUC-Oni-082190	Oryza nivara	51.20	1.00e-79	289.00
IUUC-Opu-084163	Oryza punctata	50.86	2.00e-79	289.00
IUUC-Oru-084730	Oryza rufipogon	50.86	2.00e-79	288.00
IUUC-Osa-086010	Oryza sativa	50.86	2.00e-79	289.00
IUUC-Ola-086704	Oryzias latipes	76.07	2.00e-150	524.00
IUUC-Olu-087796	Ostreococcus lucimarinus	50.17	3.00e-78	285.00
IUUC-Oga-088932	Otolemur garnettii	74.86	2.00e-128	451.00
IUUC-Oar-090398	Ovis aries	97.71	0.00e+00	645.00
IUUC-Ptr-091202	Pan troglodytes	96.57	0.00e+00	643.00
IUUC-Pan-091948	Papio anubis	96.57	0.00e+00	642.00
IUUC-Psi-093863	Pelodiscus sinensis	87.00	4.00e-154	536.00
IUUC-Pma-094255	Petromyzon marinus	80.06	1.00e-141	495.00
IUUC-Pno-095075	Phaeosphaeria nodorum	45.37	8.00e-59	220.00
IUUC-Ppa-095206	Physcomitrella patens	50.17	5.00e-81	294.00
IUUC-Pfo-096438	Poecilia formosa	77.21	1.00e-149	521.00
IUUC-Pab-097994	Pongo abelii	96.29	0.00e+00	641.00
IUUC-Pop-099172	Populus trichocarpa	50.69	7.00e-79	287.00
IUUC-Pca-100761	Procavia capensis	88.54	9.00e-157	545.00
IUUC-Ppe-102035	Prunus persica	51.55	1.00e-76	280.00
IUUC-Pva-102794	Pteropus vampyrus	89.43	2.00e-166	578.00
IUUC-Pgr-103581	Puccinia graminis	46.52	2.00e-65	242.00
IUUC-Ptt-103862	Puccinia triticina	46.93	9.00e-64	236.00
IUUC-Pte-104245	Pyrenophora teres	45.37	3.00e-58	218.00
IUUC-Pyt-104537	Pyrenophora triticirepentis	45.37	3.00e-58	218.00
IUUC-Rno-105712	Rattus norvegicus	97.43	0.00e+00	642.00
IUUC-Sha-107568	Sarcophilus harrisii	94.29	0.00e+00	631.00
IUUC-Ssl-108655	Sclerotinia sclerotiorum	39.47	2.00e-53	202.00
IUUC-Smo-108784	Selaginella moellendorffii	52.74	2.00e-82	298.00
IUUC-Sit-109807	Setaria italica	51.38	2.00e-79	289.00
IUUC-Sly-111555	Solanum lycopersicum	51.38	3.00e-78	285.00
IUUC-Stu-111953	Solanum tuberosum	50.69	2.00e-77	282.00
IUUC-Sar-113491	Sorex araneus	86.67	1.00e-119	422.00
IUUC-Sbi-114290	Sorghum bicolor	51.03	1.00e-79	289.00
IUUC-Sre-115008	Sporisorium reilianum	43.40	1.00e-63	236.00
IUUC-Ssc-116392	Sus scrofa	93.66	0.00e+00	632.00
IUUC-Tgu-116835	Taeniopygia guttata	86.98	1.00e-145	508.00
IUUC-Tru-117558	Takifugu rubripes	76.14	2.00e-149	521.00
IUUC-Tsy-119522	Tarsius syrichta	94.57	1.00e-174	605.00
IUUC-Tni-120330	Tetraodon nigroviridis	80.94	1.00e-141	495.00
IUUC-Tca-121759	Theobroma cacao	52.23	5.00e-79	287.00
IUUC-Tre-122163	Trichoderma reesei	41.19	1.00e-52	199.00
IUUC-Tvi-122609	Trichoderma virens	42.34	4.00e-53	201.00
IUUC-Tae-123053	Triticum aestivum	50.34	7.00e-78	283.00
IUUC-Tur-126808	Triticum urartu	47.29	1.00e-63	236.00
IUUC-Tme-127137	Tuber melanosporum	47.08	1.00e-67	249.00
IUUC-Tbe-127324	Tupaia belangeri	84.19	7.00e-95	340.00
IUUC-Ttr-128202	Tursiops truncatus	97.43	0.00e+00	641.00
IUUC-Uma-129433	Ustilago maydis	43.71	3.00e-63	234.00
IUUC-Vda-129675	Verticillium dahliae	39.52	4.00e-53	201.00
IUUC-Vpa-130382	Vicugna pacos	98.00	0.00e+00	646.00
IUUC-Vvi-131432	Vitis vinifera	51.89	1.00e-81	296.00
IUUC-Xtr-132648	Xenopus tropicalis	71.63	5.00e-134	470.00
IUUC-Xma-133969	Xiphophorus maculatus	73.50	3.00e-140	490.00
IUUC-Yli-134670	Yarrowia lipolytica	34.84	2.00e-44	172.00
IUUC-Zma-135878	Zea mays	51.03	1.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence