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Tag Content
UUCD2 ID IUUC-Cfa-021013
UUCD1 version UUC-CaF-00788
Ensembl Protein ID ENSCAFP00000036145.1
UniProt Accession J9NRM1; J9NRM1_CANLF
Genbank Protein ID ENSCAFP00000036145
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03006625
Gene Name NLE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000018289.4 ENSCAFT00000049920.2 ENSCAFP00000036145.1
ENSCAFG00000018289.4 ENSCAFT00000029052.2 ENSCAFP00000027015.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.20e-65 213.4 183 226
UBD/Beta-Prp 1.10e-79 268.1 92 289
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf......sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ ++t+l++      ++ ++++s+s Dg+++vWD++ g++++
   Q: 183  GHSKWITGLSWeplhanPEcRYMASSSKDGSVRVWDTTAGRCER 226
           8***************9889**********************86 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           + +sl+gh+++v +v fsp+gk+l++gs D t++ wdlst ++  t +gh + vls+s+sp+g++l+sG +   i +wd +tg+ +  +
   Q: 92   CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGKTLASGCKNGQILLWDPSTGKQVGRV 180
           5899************************************************************************************* PP
   S: 133  lsghdgvvncvvv.....hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
           l+gh+++++++++     +p++++++s+s+D+ vr+Wd   g++ r ltg ht+sv++l +  +g  l s+s+d+t+k+w  + g   r
   Q: 181  LAGHSKWITGLSWeplhaNPECRYMASSSKDGSVRVWDTTAGRCERILTG-HTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCR 267
           **********9873332257889**************************9.************98.*********************** PP
   S: 217  tlnghtdnvksvrfspnderlvs 239
           tl+gh  +v+ +++s  d  l +
   Q: 268  TLQGHGHWVNTMALS-TDYALRT 289
           **************9.4444444 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MVGVSQTVVE KNKVSAAHSP VGSAPACPLM EELPFAIALQ EDPLPLAFYV HDAEITSSLG 60
KTLESQAVET EKVLDIIYQP QAIFRVRAVT RCTSSLEGHS EAVISVAFSP TGKYLASGSG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021013|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NTTTTTGGGG GGGGGGGGGG GGGCGGGGGT 60
CCACCTGCAG GGAGCCCGGC ACCGCGTTCC CAGGCCTTGA GGCACCGTGG AATTCCCCGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021013|E3,WD_repeat;UBD,Beta-Prp|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF12894--ANAPC4_WD40
PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005840--C:ribosome
GO:0061484--P:hematopoietic stem cell homeostasis
GO:0001826--P:inner cell mass cell differentiation
GO:0001822--P:kidney development
GO:2001268--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0045930--P:negative regulation of mitotic cell cycle
GO:0007219--P:Notch signaling pathway
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0000027--P:ribosomal large subunit assembly
GO:0048705--P:skeletal system morphogenesis
GO:0001756--P:somitogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000437 Aegilops tauschii 57.71 5.00e-163 567.00
IUUC-Aml-001793 Ailuropoda melanoleuca 96.54 0.00e+00 864.00
IUUC-Atr-002507 Amborella trichopoda 58.35 2.00e-161 561.00
IUUC-Apl-003964 Anas platyrhynchos 84.92 0.00e+00 771.00
IUUC-Aly-006396 Arabidopsis lyrata 55.29 1.00e-155 542.00
IUUC-Ath-007278 Arabidopsis thaliana 55.51 2.00e-155 542.00
IUUC-Ago-007951 Ashbya gossypii 48.58 7.00e-125 440.00
IUUC-Acl-008298 Aspergillus clavatus 48.17 1.00e-115 410.00
IUUC-Afl-008581 Aspergillus flavus 51.82 2.00e-107 382.00
IUUC-Afu-008906 Aspergillus fumigatus 47.86 2.00e-116 412.00
IUUC-Ani-009189 Aspergillus nidulans 47.85 2.00e-112 399.00
IUUC-Ang-009630 Aspergillus niger 47.75 1.00e-120 426.00
IUUC-Aor-010038 Aspergillus oryzae 51.12 3.00e-122 432.00
IUUC-Ate-010278 Aspergillus terreus 47.88 7.00e-118 417.00
IUUC-Ame-011890 Astyanax mexicanus 78.98 0.00e+00 742.00
IUUC-Bgr-012011 Blumeria graminis 51.61 1.00e-125 442.00
IUUC-Bta-012964 Bos taurus 95.15 0.00e+00 854.00
IUUC-Bci-013592 Botrytis cinerea 46.40 1.00e-117 416.00
IUUC-Bdi-015035 Brachypodium distachyon 58.73 6.00e-164 570.00
IUUC-Bol-015501 Brassica oleracea 55.80 4.00e-156 544.00
IUUC-Bra-017642 Brassica rapa 55.58 2.00e-155 541.00
IUUC-Cel-018430 Caenorhabditis elegans 59.07 9.00e-158 549.00
IUUC-Cja-019125 Callithrix jacchus 94.46 0.00e+00 849.00
IUUC-Cpo-021743 Cavia porcellus 94.46 0.00e+00 852.00
IUUC-Cre-022973 Chlamydomonas reinhardtii 46.15 5.00e-106 377.00
IUUC-Csa-024270 Chlorocebus sabaeus 95.38 0.00e+00 857.00
IUUC-Cin-025795 Ciona intestinalis 66.97 0.00e+00 649.00
IUUC-Csv-025953 Ciona savignyi 67.65 0.00e+00 646.00
IUUC-Cgl-026517 Colletotrichum gloeosporioides 51.33 6.00e-107 380.00
IUUC-Cne-026901 Cryptococcus neoformans 50.22 2.00e-130 459.00
IUUC-Cme-027281 Cyanidioschyzon merolae 47.59 2.00e-114 406.00
IUUC-Dre-028515 Danio rerio 77.37 0.00e+00 728.00
IUUC-Dno-029596 Dasypus novemcinctus 95.84 0.00e+00 857.00
IUUC-Dor-030494 Dipodomys ordii 94.93 0.00e+00 852.00
IUUC-Dse-031538 Dothistroma septosporum 48.85 4.00e-123 434.00
IUUC-Dme-031974 Drosophila melanogaster 59.35 8.00e-159 553.00
IUUC-Ete-032948 Echinops telfairi 95.63 3.00e-115 408.00
IUUC-Eca-033399 Equus caballus 97.00 0.00e+00 866.00
IUUC-Eeu-035013 Erinaceus europaeus 95.15 5.00e-115 407.00
IUUC-Fca-035860 Felis catus 95.61 0.00e+00 854.00
IUUC-Fal-037069 Ficedula albicollis 88.26 7.00e-131 459.00
IUUC-Fox-038059 Fusarium oxysporum 48.41 2.00e-122 432.00
IUUC-Fso-038445 Fusarium solani 48.64 2.00e-122 432.00
IUUC-Gmo-039319 Gadus morhua 74.60 0.00e+00 662.00
IUUC-Ggr-040095 Gaeumannomyces graminis 44.97 2.00e-118 419.00
IUUC-Gga-040303 Gallus gallus 86.23 4.00e-129 453.00
IUUC-Gac-042267 Gasterosteus aculeatus 76.73 0.00e+00 683.00
IUUC-Gma-043974 Glycine max 55.28 2.00e-163 568.00
IUUC-Ggo-044637 Gorilla gorilla 95.15 0.00e+00 852.00
IUUC-Hsa-046128 Homo sapiens 95.61 0.00e+00 859.00
IUUC-Hvu-047373 Hordeum vulgare 57.49 1.00e-162 566.00
IUUC-Itr-048070 Ictidomys tridecemlineatus 94.75 0.00e+00 857.00
IUUC-Kpa-049274 Komagataella pastoris 45.98 5.00e-121 427.00
IUUC-Lch-049907 Latimeria chalumnae 81.42 0.00e+00 741.00
IUUC-Lpe-050778 Leersia perrieri 57.52 2.00e-146 511.00
IUUC-Loc-051889 Lepisosteus oculatus 80.37 0.00e+00 754.00
IUUC-Lma-053041 Leptosphaeria maculans 48.60 5.00e-116 411.00
IUUC-Laf-053598 Loxodonta africana 95.84 0.00e+00 858.00
IUUC-Mcc-055660 Macaca mulatta 95.15 0.00e+00 855.00
IUUC-Meu-056197 Macropus eugenii 78.01 0.00e+00 697.00
IUUC-Mor-056949 Magnaporthe oryzae 49.29 8.00e-116 410.00
IUUC-Mpo-057571 Magnaporthe poae 44.75 5.00e-63 234.00
IUUC-Mtr-058530 Medicago truncatula 60.28 5.00e-162 563.00
IUUC-Mla-059133 Melampsora laricipopulina 52.97 4.00e-124 438.00
IUUC-Mga-059252 Meleagris gallopavo 84.53 0.00e+00 657.00
IUUC-Mvi-060522 Microbotryum violaceum 52.01 1.00e-130 460.00
IUUC-Mmr-061117 Microcebus murinus 95.38 0.00e+00 856.00
IUUC-Mdo-062892 Monodelphis domestica 88.45 0.00e+00 804.00
IUUC-Mmu-064108 Mus musculus 94.77 0.00e+00 832.00
IUUC-Mac-064430 Musa acuminata 59.47 5.00e-166 577.00
IUUC-Mpu-065882 Mustela putorius furo 96.30 0.00e+00 857.00
IUUC-Mlu-068123 Myotis lucifugus 95.38 0.00e+00 857.00
IUUC-Nfi-068484 Neosartorya fischeri 47.95 6.00e-116 410.00
IUUC-Ncr-068649 Neurospora crassa 45.23 2.00e-111 396.00
IUUC-Nle-069140 Nomascus leucogenys 95.38 0.00e+00 854.00
IUUC-Opr-070220 Ochotona princeps 86.94 0.00e+00 746.00
IUUC-Ont-072643 Oreochromis niloticus 78.57 0.00e+00 736.00
IUUC-Ocu-074007 Oryctolagus cuniculus 95.72 0.00e+00 835.00
IUUC-Oba-075904 Oryza barthii 58.59 3.00e-166 578.00
IUUC-Obr-076280 Oryza brachyantha 58.15 3.00e-165 574.00
IUUC-Ogl-077425 Oryza glaberrima 58.59 3.00e-166 578.00
IUUC-Ogu-078586 Oryza glumaepatula 58.59 4.00e-166 577.00
IUUC-Oin-079489 Oryza indica 56.39 6.00e-157 546.00
IUUC-Olo-080587 Oryza longistaminata 60.98 3.00e-166 579.00
IUUC-Ome-081905 Oryza meridionalis 58.59 5.00e-166 577.00
IUUC-Oni-083022 Oryza nivara 58.59 3.00e-166 578.00
IUUC-Opu-083615 Oryza punctata 58.59 2.00e-166 578.00
IUUC-Oru-085076 Oryza rufipogon 58.59 3.00e-166 578.00
IUUC-Osa-085744 Oryza sativa 58.81 8.00e-167 580.00
IUUC-Ola-087290 Oryzias latipes 76.96 0.00e+00 726.00
IUUC-Olu-087898 Ostreococcus lucimarinus 56.94 3.00e-143 501.00
IUUC-Oga-088980 Otolemur garnettii 95.38 0.00e+00 855.00
IUUC-Oar-089580 Ovis aries 95.16 0.00e+00 738.00
IUUC-Ptr-090845 Pan troglodytes 94.92 0.00e+00 848.00
IUUC-Pan-092836 Papio anubis 94.92 0.00e+00 855.00
IUUC-Psi-093965 Pelodiscus sinensis 81.82 3.00e-34 136.00
IUUC-Pno-095052 Phaeosphaeria nodorum 47.73 3.00e-118 418.00
IUUC-Ppa-095432 Physcomitrella patens 60.61 1.00e-161 562.00
IUUC-Pfo-096963 Poecilia formosa 69.59 2.00e-178 618.00
IUUC-Pab-097716 Pongo abelii 91.45 0.00e+00 808.00
IUUC-Pop-099224 Populus trichocarpa 58.77 2.00e-161 562.00
IUUC-Pca-100682 Procavia capensis 91.32 0.00e+00 677.00
IUUC-Ppe-101819 Prunus persica 58.33 4.00e-163 567.00
IUUC-Pva-102338 Pteropus vampyrus 95.31 0.00e+00 639.00
IUUC-Pgr-103583 Puccinia graminis 54.66 3.00e-131 461.00
IUUC-Ptt-103737 Puccinia triticina 44.52 3.00e-100 358.00
IUUC-Pte-104150 Pyrenophora teres 48.98 4.00e-119 421.00
IUUC-Pyt-104606 Pyrenophora triticirepentis 48.75 7.00e-119 421.00
IUUC-Rno-105987 Rattus norvegicus 93.76 0.00e+00 847.00
IUUC-Sce-106315 Saccharomyces cerevisiae 49.22 6.00e-129 454.00
IUUC-Sha-107273 Sarcophilus harrisii 89.15 0.00e+00 816.00
IUUC-Sja-107677 Schizosaccharomyces japonicus 48.42 9.00e-116 410.00
IUUC-Spo-108092 Schizosaccharomyces pombe 48.39 1.00e-122 433.00
IUUC-Ssl-108442 Sclerotinia sclerotiorum 49.09 1.00e-112 400.00
IUUC-Smo-108855 Selaginella moellendorffii 56.58 1.00e-155 543.00
IUUC-Sit-110329 Setaria italica 59.03 3.00e-166 578.00
IUUC-Sly-111830 Solanum lycopersicum 59.21 3.00e-167 581.00
IUUC-Stu-112603 Solanum tuberosum 59.21 4.00e-167 581.00
IUUC-Sar-113504 Sorex araneus 91.35 7.00e-52 198.00
IUUC-Sbi-114560 Sorghum bicolor 59.18 3.00e-164 571.00
IUUC-Sre-115133 Sporisorium reilianum 44.23 2.00e-120 426.00
IUUC-Ssc-115903 Sus scrofa 96.30 0.00e+00 858.00
IUUC-Tgu-116798 Taeniopygia guttata 84.99 0.00e+00 783.00
IUUC-Tru-118361 Takifugu rubripes 77.19 0.00e+00 724.00
IUUC-Tsy-118849 Tarsius syrichta 95.83 0.00e+00 858.00
IUUC-Tni-120094 Tetraodon nigroviridis 76.96 0.00e+00 723.00
IUUC-Tca-121634 Theobroma cacao 59.09 2.00e-161 561.00
IUUC-Tre-122051 Trichoderma reesei 48.19 2.00e-117 416.00
IUUC-Tvi-122322 Trichoderma virens 49.55 7.00e-122 430.00
IUUC-Tae-125822 Triticum aestivum 57.71 4.00e-163 567.00
IUUC-Tur-126766 Triticum urartu 56.49 4.00e-159 554.00
IUUC-Tme-127175 Tuber melanosporum 53.98 1.00e-126 446.00
IUUC-Tbe-127779 Tupaia belangeri 94.61 0.00e+00 831.00
IUUC-Ttr-128224 Tursiops truncatus 92.06 0.00e+00 813.00
IUUC-Uma-129537 Ustilago maydis 45.82 2.00e-122 433.00
IUUC-Vda-129927 Verticillium dahliae 45.28 1.00e-105 377.00
IUUC-Vpa-130658 Vicugna pacos 81.99 0.00e+00 714.00
IUUC-Vvi-131659 Vitis vinifera 57.91 1.00e-161 563.00
IUUC-Xtr-132918 Xenopus tropicalis 75.81 0.00e+00 712.00
IUUC-Xma-133700 Xiphophorus maculatus 78.57 0.00e+00 731.00
IUUC-Yli-134478 Yarrowia lipolytica 51.80 1.00e-134 473.00
IUUC-Zma-135835 Zea mays 55.42 6.00e-160 557.00
Created Date 25-Jun-2017

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