iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033760

Ensembl Protein ID

ENSECAP00000019628.1

UniProt Accession

F6Z263; F6Z263_HORSE

Protein Name

Uncharacterized protein

Gene Name

STRN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000021926.1	ENSECAT00000023682.1	ENSECAP00000019628.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-31	105.0	490	522
UBD/Beta-Prp	3.50e-46	157.9	486	700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlr 31
           gHtd v++la+   +  +l+s+s Dgt+++W+++
   Q: 490  GHTDAVWGLAYsaaH-QRLLSCSADGTLRLWNTT 522
           8**********9853.89**************76 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlk......ghedsvlslsfspsgdklvsGshdrtirvwdletgqc 128
             l gh+++v+ + +s   + l+++s D+t+++w+     +  ++       g  +sv ++s++p  +++v+  +  +  ++++et+q 
   Q: 486  GPLLGHTDAVWGLAYSAAHQRLLSCSADGTLRLWNTTEVAPALSVFndnqelGIPASVDLVSSDP--SHMVASFSKGYTSIFNMETQQR 572
           5689******************************8887766666661444444444555566666..8888888899************ PP
   S: 129  lee......tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqt 211
           + +      t +  +  +n v +hp+  + ++++ Dr ++++d +tgkl++ +   h ++v+sl++d+ng +l+sgs+d +++lw+l++
   Q: 573  ILTlesnpdTIASSSCQINRVISHPTLPISITAHEDRHIKFYDNNTGKLIHSMVA-HLEAVTSLAVDPNGLYLMSGSHDCSIRLWNLES 660
           **999997766666667888899**99**************************98.********************************* PP
   S: 212  gecvrtlnght....dnvksvrfspnderlvsgssDgsir 247
           ++c++++++h+    + + +v+f+p + +++s+++D   +
   Q: 661  KTCIQEFTAHRkkfeESIHDVAFHPSKCYIASAGADALAK 700
           ***********999999******************97665 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

QAQIAFLQGE RKGQENLKKD LVRRIKMLEY ALKQERAKYH KLKYGTELNQ GDMKPPSYDS 60
DEGNETEMQP QQNSQLMWKQ GRQLLRQYLQ EVGYTDTILD VKSKRVRALL GFPSDVTDRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGCCCAGA TTGCCTTCCT TCAGGGGGAA AGGAAAGGTC AAGAAAATTT GAAGAAGGAT 60
CTTGTGAGGA GGATCAAAAT GCTGGAGTAT GCTCTTAAAC AGGAAAGGTA ATTTCAGTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005923--C:bicellular tight junction
GO:0000159--C:protein phosphatase type 2A complex
GO:0008285--P:negative regulation of cell proliferation
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001899	Ailuropoda melanoleuca	98.15	0.00e+00	1293.00
IUUC-Apl-003927	Anas platyrhynchos	87.93	0.00e+00	1120.00
IUUC-Aca-004933	Anolis carolinensis	80.33	0.00e+00	1129.00
IUUC-Ame-010997	Astyanax mexicanus	74.72	0.00e+00	979.00
IUUC-Bta-013077	Bos taurus	97.58	0.00e+00	1283.00
IUUC-Cja-018973	Callithrix jacchus	98.15	0.00e+00	1293.00
IUUC-Cfa-020988	Canis familiaris	94.59	0.00e+00	1236.00
IUUC-Cpo-022496	Cavia porcellus	96.59	0.00e+00	1285.00
IUUC-Csa-023829	Chlorocebus sabaeus	97.87	0.00e+00	1287.00
IUUC-Dre-028560	Danio rerio	69.18	0.00e+00	884.00
IUUC-Dno-029742	Dasypus novemcinctus	90.75	0.00e+00	1214.00
IUUC-Dor-030721	Dipodomys ordii	88.05	0.00e+00	1149.00
IUUC-Eeu-034953	Erinaceus europaeus	96.61	0.00e+00	749.00
IUUC-Fca-036530	Felis catus	97.44	0.00e+00	1288.00
IUUC-Fal-037353	Ficedula albicollis	81.98	0.00e+00	895.00
IUUC-Gmo-039653	Gadus morhua	50.28	0.00e+00	644.00
IUUC-Gga-040132	Gallus gallus	88.05	0.00e+00	1113.00
IUUC-Gac-041713	Gasterosteus aculeatus	74.23	0.00e+00	968.00
IUUC-Ggo-045455	Gorilla gorilla	86.99	0.00e+00	1090.00
IUUC-Hsa-046415	Homo sapiens	97.72	0.00e+00	1287.00
IUUC-Lch-050475	Latimeria chalumnae	83.55	0.00e+00	1102.00
IUUC-Loc-051859	Lepisosteus oculatus	78.96	0.00e+00	1046.00
IUUC-Laf-053537	Loxodonta africana	97.01	0.00e+00	1300.00
IUUC-Mcc-055817	Macaca mulatta	97.87	0.00e+00	1287.00
IUUC-Meu-055946	Macropus eugenii	67.81	0.00e+00	790.00
IUUC-Mga-059694	Meleagris gallopavo	88.05	0.00e+00	1114.00
IUUC-Mmr-060768	Microcebus murinus	98.29	0.00e+00	1289.00
IUUC-Mdo-061901	Monodelphis domestica	87.84	0.00e+00	1201.00
IUUC-Mmu-064154	Mus musculus	96.02	0.00e+00	1273.00
IUUC-Mpu-065827	Mustela putorius furo	92.08	0.00e+00	1272.00
IUUC-Mlu-067102	Myotis lucifugus	96.87	0.00e+00	1276.00
IUUC-Ncr-068831	Neurospora crassa	39.60	5.00e-22	99.80
IUUC-Nle-070008	Nomascus leucogenys	97.87	0.00e+00	1290.00
IUUC-Opr-071067	Ochotona princeps	63.40	5.00e-166	577.00
IUUC-Ont-072025	Oreochromis niloticus	73.77	0.00e+00	957.00
IUUC-Oan-072950	Ornithorhynchus anatinus	91.32	0.00e+00	1161.00
IUUC-Ocu-074316	Oryctolagus cuniculus	96.73	0.00e+00	1271.00
IUUC-Ola-087279	Oryzias latipes	71.59	0.00e+00	935.00
IUUC-Oga-088284	Otolemur garnettii	97.58	0.00e+00	1288.00
IUUC-Oar-090304	Ovis aries	98.01	0.00e+00	1290.00
IUUC-Ptr-091052	Pan troglodytes	97.87	0.00e+00	1289.00
IUUC-Pan-092270	Papio anubis	93.62	0.00e+00	1248.00
IUUC-Psi-093907	Pelodiscus sinensis	87.89	0.00e+00	1038.00
IUUC-Pfo-097042	Poecilia formosa	72.83	0.00e+00	1031.00
IUUC-Pab-098110	Pongo abelii	97.87	0.00e+00	1289.00
IUUC-Pca-100266	Procavia capensis	83.17	0.00e+00	885.00
IUUC-Pva-102824	Pteropus vampyrus	95.45	0.00e+00	1236.00
IUUC-Pgr-103483	Puccinia graminis	36.99	2.00e-56	214.00
IUUC-Rno-105638	Rattus norvegicus	96.16	0.00e+00	1276.00
IUUC-Sha-107004	Sarcophilus harrisii	88.10	0.00e+00	1117.00
IUUC-Sre-115115	Sporisorium reilianum	33.85	5.00e-64	239.00
IUUC-Ssc-115280	Sus scrofa	97.72	0.00e+00	1287.00
IUUC-Tgu-116759	Taeniopygia guttata	88.19	0.00e+00	1140.00
IUUC-Tru-117944	Takifugu rubripes	73.77	0.00e+00	961.00
IUUC-Tsy-119405	Tarsius syrichta	86.04	0.00e+00	1073.00
IUUC-Tni-120571	Tetraodon nigroviridis	73.01	0.00e+00	963.00
IUUC-Tme-126990	Tuber melanosporum	25.91	1.00e-35	144.00
IUUC-Uma-129659	Ustilago maydis	34.70	1.00e-64	241.00
IUUC-Vpa-130294	Vicugna pacos	97.15	0.00e+00	1271.00
IUUC-Xma-134233	Xiphophorus maculatus	66.71	0.00e+00	872.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence