iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053649

UUCD1 version

UUC-LoA-00397

Ensembl Protein ID

ENSLAFP00000009720.2

UniProt Accession

G3T7V9; G3T7V9_LOXAF

Protein Name

Uncharacterized protein

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000020864.3	ENSLAFT00000020496.3	ENSLAFP00000015938.3
ENSLAFG00000020864.3	ENSLAFT00000011636.2	ENSLAFP00000009720.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.60e-59	194.8	107	146
UBD/Beta-Prp	2.40e-133	444.3	727	945

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvllk 37
           Ht +v claf sd  +l+s + D  +t+ +WD+r+g+ll 
   Q: 107  HTHGVACLAFdSDgQRLASVGLDakNTVCIWDWRKGKLLA 146
           99*********999*******9999***********9875 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++atg  +rd+ + vwd++t k+l+ l  +h+ +v a++fs dgk lv+++ D  + i  wd ++g+ + t 
   Q: 727  GHDDDILS-LTIHPVKDYVATGqvGRDAAVHVWDTQTLKCLSLLkGQHQRGVCALDFSADGKCLVSVGLDdfHSIVFWDWKKGEKIATT 814
           45555555.999*********95569******************7789**********************77788889*********** PP
   S: 91   kghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ +p   dklv+ +  + i+ w+   g   ++       g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t
   Q: 815  RGHKDKIFVIKCNPHHvDKLVTVG-MKHIKFWQQAGGGFTSKrgifGSVGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDILLLKT 900
           **************7769999988.99*****9888888887998777899999*************************..889***** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 901  VKA-HDGPVFAMYALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKR 945
           *98.*******99888..57*********************9997655 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MGGSNSSSCQ LRLEWVYGYR GHQCRNNLEL HGRQGRWSTF GAGAGVVVQT AGEHSQKFLP 60
GHNDDLLHLA LHPDKTLVAT GQVGKEPYIC VWDSYNVQTV SILKDVHTHG VACLAFDSDG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGGGAT CGAACAGCTC CAGCTGCCAG CTCCGGCTGG AGTGGGGTGT ACGGGTACCG 60
GGGGCCACCA GTGCCGCAAC AACCTGGAAC TACACGGCCG GCAAGGGAGG TGGTCTACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR011048--Haem_d1
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	95.92	0.00e+00	3799.00
IUUC-Apl-003604	Anas platyrhynchos	91.92	0.00e+00	3635.00
IUUC-Aca-004572	Anolis carolinensis	87.89	0.00e+00	3530.00
IUUC-Ame-010713	Astyanax mexicanus	79.04	0.00e+00	3145.00
IUUC-Bta-012812	Bos taurus	95.56	0.00e+00	3782.00
IUUC-Cja-019191	Callithrix jacchus	96.20	0.00e+00	3742.00
IUUC-Cfa-020041	Canis familiaris	95.91	0.00e+00	3525.00
IUUC-Csa-023689	Chlorocebus sabaeus	96.13	0.00e+00	3696.00
IUUC-Cho-025038	Choloepus hoffmanni	96.74	0.00e+00	1488.00
IUUC-Cin-025205	Ciona intestinalis	61.52	0.00e+00	2520.00
IUUC-Csv-026014	Ciona savignyi	62.21	0.00e+00	2535.00
IUUC-Dno-029982	Dasypus novemcinctus	95.54	0.00e+00	3662.00
IUUC-Eca-034161	Equus caballus	96.00	0.00e+00	3669.00
IUUC-Fca-036307	Felis catus	96.22	0.00e+00	3800.00
IUUC-Fal-037332	Ficedula albicollis	90.66	0.00e+00	3558.00
IUUC-Gmo-039057	Gadus morhua	73.53	0.00e+00	2921.00
IUUC-Gac-042555	Gasterosteus aculeatus	78.68	0.00e+00	3179.00
IUUC-Ggo-045107	Gorilla gorilla	95.61	0.00e+00	3784.00
IUUC-Hsa-046482	Homo sapiens	95.71	0.00e+00	3788.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	95.53	0.00e+00	3707.00
IUUC-Loc-052642	Lepisosteus oculatus	86.27	0.00e+00	3421.00
IUUC-Mcc-055361	Macaca mulatta	96.79	0.00e+00	3353.00
IUUC-Meu-056618	Macropus eugenii	75.38	0.00e+00	1743.00
IUUC-Mga-059202	Meleagris gallopavo	92.35	0.00e+00	3560.00
IUUC-Mmr-060729	Microcebus murinus	93.27	0.00e+00	3751.00
IUUC-Mdo-062462	Monodelphis domestica	94.88	0.00e+00	3661.00
IUUC-Mmu-063865	Mus musculus	94.85	0.00e+00	3774.00
IUUC-Mpu-066724	Mustela putorius furo	96.38	0.00e+00	3809.00
IUUC-Mlu-067816	Myotis lucifugus	95.37	0.00e+00	3789.00
IUUC-Opr-070213	Ochotona princeps	93.57	0.00e+00	1985.00
IUUC-Ont-071928	Oreochromis niloticus	78.24	0.00e+00	3197.00
IUUC-Oan-073563	Ornithorhynchus anatinus	93.13	0.00e+00	3702.00
IUUC-Ocu-074531	Oryctolagus cuniculus	95.71	0.00e+00	3790.00
IUUC-Ola-086943	Oryzias latipes	78.69	0.00e+00	3132.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.17	4.00e-118	418.00
IUUC-Oga-088665	Otolemur garnettii	96.16	0.00e+00	3674.00
IUUC-Oar-090429	Ovis aries	95.82	0.00e+00	3792.00
IUUC-Ptr-091168	Pan troglodytes	86.78	0.00e+00	3370.00
IUUC-Pan-092788	Papio anubis	96.60	0.00e+00	3038.00
IUUC-Psi-093281	Pelodiscus sinensis	90.60	0.00e+00	3575.00
IUUC-Pma-094424	Petromyzon marinus	72.46	6.00e-124	436.00
IUUC-Pab-098561	Pongo abelii	94.30	0.00e+00	3274.00
IUUC-Rno-105002	Rattus norvegicus	94.03	0.00e+00	3761.00
IUUC-Sha-107105	Sarcophilus harrisii	92.36	0.00e+00	3544.00
IUUC-Ssc-116282	Sus scrofa	97.26	0.00e+00	3733.00
IUUC-Tgu-116807	Taeniopygia guttata	91.84	0.00e+00	3622.00
IUUC-Tru-118040	Takifugu rubripes	77.06	0.00e+00	3116.00
IUUC-Tni-120118	Tetraodon nigroviridis	74.80	0.00e+00	3090.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence