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Tag Content
UUCD2 ID IUUC-Bta-013202
UUCD1 version UUC-BoT-00119
Ensembl Protein ID ENSBTAP00000024105.5
UniProt Accession B7TCI5; B7TCI5_BOVIN
Genbank Protein ID ACJ61274.1
Protein Name Transducin beta-like 1
Genbank Nucleotide ID DAAA02075574
Gene Name TBL1Y; TBL1X
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000018112.5 ENSBTAT00000024105.5 ENSBTAP00000024105.5
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 9.20e-54 177.1 455 493
UBD/Beta-Prp 1.20e-64 218.4 325 527
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+++v+++af +d ++l+sGs D+ +++W++ +g l++s
   Q: 455  HQEPVYSVAFsPDgKYLASGSFDKCVHIWNTQSGSLVHS 493
           9**********999******************9999875 PP
   

   UBD/Beta-Prp
   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
             +v++ ++++ +a+ s+d +i v ++     +++++gh++ev+a+k++p+g +l+++s+D+t+k+w++++ +cvh l++h++++++++
   Q: 325  ALDVDW-QNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDTCVHDLQAHSKEIYTIK 412
           444555.6667777777777777777777777778888888888888888877778888888888888888888888888888888877 PP
   S: 102  fsp.........sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtd 181
           +sp         s+  l+s+s d+t+r+wd+e g cl+ tl++h++ v +v+++pdg++l+sGs D++v +W+ ++g+l++  +g  t+
   Q: 413  WSPtgpatsnpnSSIMLASASFDSTVRLWDVERGVCLH-TLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYRG--TG 498
           77755555544333567777788888888888888887.7888888888888888778888888888888888888888888877..77 PP
   S: 182  svyslsfdsngkelvsgsldgtvklwdlq 210
            +  + ++  g  + + + dg+v + dl+
   Q: 499  GIFEVCWNARGDKVGASASDGSVCVLDLR 527
           77777777777777777777777777765 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
MSITSDEVNF LVYRYLQESG FSHSAFTFGI ESHISQSNIN GTLVPPAALI SILQKGLQYV 60
EAEISINEDG TVFDGRPIES LSLIDAVMPD VVQTRQQAFR EKLAQQQAAA AAAAAAAAAA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-013202|E3,WD_repeat;UBD,Beta-Prp|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGAGCATTA CCAGTGACGA GGTGAACTTC CTGGTGTACC GATATCTCCA GGAGTCAGGT 60
AAGAAGCCGG CTTCCTGCCC GGAGCGGCAA AAAAAACACC TTCCAACACG CCACCTGCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-013202|E3,WD_repeat;UBD,Beta-Prp|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR008207--Sig_transdc_His_kin_Hpt_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08513--LisH
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00667--LisH
SM00320--WD40
Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005876--C:spindle microtubule
GO:0005667--C:transcription factor complex
GO:0017053--C:transcriptional repressor complex
GO:0008013--F:beta-catenin binding
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0003714--F:transcription corepressor activity
GO:0044212--F:transcription regulatory region DNA binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0045444--P:fat cell differentiation
GO:0016575--P:histone deacetylation
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006508--P:proteolysis
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0043627--P:response to estrogen
GO:0048545--P:response to steroid hormone
GO:0007605--P:sensory perception of sound
KEGG bta:515972
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001450 Ailuropoda melanoleuca 92.42 0.00e+00 994.00
IUUC-Apl-003232 Anas platyrhynchos 95.83 0.00e+00 998.00
IUUC-Aca-005035 Anolis carolinensis 94.51 0.00e+00 999.00
IUUC-Aly-005622 Arabidopsis lyrata 56.10 2.00e-119 423.00
IUUC-Ath-007137 Arabidopsis thaliana 59.50 7.00e-121 427.00
IUUC-Bdi-014315 Brachypodium distachyon 61.19 2.00e-134 472.00
IUUC-Cja-019281 Callithrix jacchus 91.48 0.00e+00 980.00
IUUC-Cfa-020929 Canis familiaris 96.78 0.00e+00 1005.00
IUUC-Cre-022979 Chlamydomonas reinhardtii 61.98 3.00e-132 465.00
IUUC-Csa-023943 Chlorocebus sabaeus 93.18 0.00e+00 981.00
IUUC-Cin-025704 Ciona intestinalis 72.09 0.00e+00 793.00
IUUC-Dno-028926 Dasypus novemcinctus 96.40 0.00e+00 997.00
IUUC-Dme-031939 Drosophila melanogaster 81.47 3.00e-176 611.00
IUUC-Ete-032822 Echinops telfairi 84.66 0.00e+00 846.00
IUUC-Eca-033897 Equus caballus 97.35 0.00e+00 1009.00
IUUC-Fca-036462 Felis catus 97.54 0.00e+00 1007.00
IUUC-Fal-037388 Ficedula albicollis 96.02 0.00e+00 1006.00
IUUC-Gga-040671 Gallus gallus 95.83 0.00e+00 1006.00
IUUC-Gac-041851 Gasterosteus aculeatus 88.64 0.00e+00 935.00
IUUC-Ggo-045373 Gorilla gorilla 93.94 0.00e+00 989.00
IUUC-Hsa-045841 Homo sapiens 94.51 0.00e+00 989.00
IUUC-Itr-048236 Ictidomys tridecemlineatus 98.92 0.00e+00 779.00
IUUC-Lch-050535 Latimeria chalumnae 91.67 0.00e+00 981.00
IUUC-Laf-054071 Loxodonta africana 96.79 0.00e+00 1006.00
IUUC-Mcc-055233 Macaca mulatta 92.71 0.00e+00 965.00
IUUC-Mga-059895 Meleagris gallopavo 96.40 0.00e+00 1006.00
IUUC-Mvi-060557 Microbotryum violaceum 37.30 2.00e-70 260.00
IUUC-Mmr-061286 Microcebus murinus 96.60 0.00e+00 1013.00
IUUC-Mmu-063447 Mus musculus 97.35 0.00e+00 1009.00
IUUC-Mac-065508 Musa acuminata 61.42 1.00e-91 330.00
IUUC-Nle-069151 Nomascus leucogenys 93.18 0.00e+00 985.00
IUUC-Ont-072252 Oreochromis niloticus 89.39 0.00e+00 959.00
IUUC-Oan-073562 Ornithorhynchus anatinus 96.97 0.00e+00 1010.00
IUUC-Opu-083505 Oryza punctata 48.47 9.00e-144 503.00
IUUC-Oar-089506 Ovis aries 95.27 0.00e+00 1013.00
IUUC-Ptr-090793 Pan troglodytes 92.23 0.00e+00 954.00
IUUC-Pan-091909 Papio anubis 93.60 0.00e+00 988.00
IUUC-Psi-093358 Pelodiscus sinensis 91.44 0.00e+00 957.00
IUUC-Ppa-095868 Physcomitrella patens 66.30 2.00e-139 489.00
IUUC-Pfo-097214 Poecilia formosa 87.69 0.00e+00 926.00
IUUC-Pab-098317 Pongo abelii 94.21 0.00e+00 968.00
IUUC-Pop-098989 Populus trichocarpa 58.15 1.00e-129 456.00
IUUC-Ppe-101572 Prunus persica 63.97 4.00e-128 451.00
IUUC-Rno-105857 Rattus norvegicus 97.35 0.00e+00 1009.00
IUUC-Sha-107326 Sarcophilus harrisii 94.32 0.00e+00 1013.00
IUUC-Ssc-115646 Sus scrofa 97.54 0.00e+00 1017.00
IUUC-Tgu-116898 Taeniopygia guttata 96.02 0.00e+00 1000.00
IUUC-Tru-117862 Takifugu rubripes 89.58 0.00e+00 946.00
IUUC-Tni-119656 Tetraodon nigroviridis 90.34 0.00e+00 946.00
IUUC-Tca-121739 Theobroma cacao 54.55 8.00e-125 441.00
IUUC-Tae-125368 Triticum aestivum 59.38 6.00e-135 474.00
IUUC-Ttr-128826 Tursiops truncatus 96.09 0.00e+00 922.00
IUUC-Uma-129469 Ustilago maydis 43.53 1.00e-58 221.00
IUUC-Vvi-131193 Vitis vinifera 57.39 4.00e-130 458.00
IUUC-Xma-133591 Xiphophorus maculatus 87.88 0.00e+00 927.00
Created Date 25-Jun-2017

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