iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066655

Ensembl Protein ID

ENSMPUP00000006254.1

UniProt Accession

M3Y4K3; M3Y4K3_MUSPF

Genbank Protein ID

ENSMPUP00000006254

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01068451

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000006308.1	ENSMPUT00000006363.1	ENSMPUP00000006254.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.20e-06	28.1	351	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ +  Cl +w       s +++CP Cr
   Q: 351  CKICAESVKD-VKIEPCGHLLCSRCLAAW-----RHSDSQTCPFCR 390
           99********.******************.....5788889****8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAAAADPWGW PSGEARALGR AVRRLQRLEG QCGDPRLASS PPSLRDLLPR IVQLLRQVAH 60
ARRAAGGGGP EGPGGARDFL IVHLHNLEAK SRQVAALLPP RGERTANDEL FREGSRLRRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCCGCCCC CACCCTGGGC GGGGCCGCAC CTTGGCCTGC CGCGGGCCTA CCTTCCCCGG 60
AACCCGGGGG CCCATGGCTG CCGCGGCAGA CCCCTGGGGG TGGCCGTCGG GAGAGGCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	87.79	0.00e+00	780.00
IUUC-Bta-012705	Bos taurus	75.62	0.00e+00	661.00
IUUC-Cja-019179	Callithrix jacchus	79.49	0.00e+00	645.00
IUUC-Cfa-020593	Canis familiaris	82.75	0.00e+00	729.00
IUUC-Cpo-021289	Cavia porcellus	75.84	4.00e-169	587.00
IUUC-Csa-023966	Chlorocebus sabaeus	83.79	7.00e-180	623.00
IUUC-Dor-030246	Dipodomys ordii	77.05	1.00e-125	443.00
IUUC-Eca-033921	Equus caballus	75.54	3.00e-147	514.00
IUUC-Fca-035747	Felis catus	67.63	5.00e-174	603.00
IUUC-Ggo-044622	Gorilla gorilla	83.60	2.00e-149	521.00
IUUC-Hsa-045735	Homo sapiens	82.03	0.00e+00	664.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	73.10	2.00e-167	581.00
IUUC-Laf-053983	Loxodonta africana	72.92	0.00e+00	687.00
IUUC-Mmr-061310	Microcebus murinus	82.04	0.00e+00	643.00
IUUC-Mmu-064155	Mus musculus	71.46	0.00e+00	631.00
IUUC-Mlu-067929	Myotis lucifugus	84.49	7.00e-155	539.00
IUUC-Nle-070065	Nomascus leucogenys	70.43	4.00e-151	527.00
IUUC-Ocu-074049	Oryctolagus cuniculus	75.70	6.00e-125	440.00
IUUC-Oga-087952	Otolemur garnettii	80.14	0.00e+00	674.00
IUUC-Oar-089382	Ovis aries	72.55	1.00e-180	625.00
IUUC-Pan-092075	Papio anubis	83.54	2.00e-178	618.00
IUUC-Pab-098100	Pongo abelii	72.81	3.00e-162	564.00
IUUC-Pca-100830	Procavia capensis	80.24	2.00e-111	395.00
IUUC-Pva-102714	Pteropus vampyrus	78.31	9.00e-165	573.00
IUUC-Pgr-103631	Puccinia graminis	35.21	1.00e-05	42.70
IUUC-Rno-105348	Rattus norvegicus	73.48	0.00e+00	627.00
IUUC-Sha-107138	Sarcophilus harrisii	69.47	2.00e-120	425.00
IUUC-Ssc-116424	Sus scrofa	76.35	0.00e+00	712.00
IUUC-Ttr-128807	Tursiops truncatus	85.82	2.00e-136	478.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence