iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092075

Ensembl Protein ID

ENSPANP00000010399.1

UniProt Accession

A0A0A0MWV7; A0A0A0MWV7_PAPAN

Genbank Protein ID

ENSPANP00000010399

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01095952

Gene Name

CBLC

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000007942.1	ENSPANT00000017968.1	ENSPANP00000010399.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.20e-06	27.3	351	390

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC e+ kd +++ pCgH+ +  Cl +w     + s +++CP Cr
   Q: 351  CKICAESNKD-VKIEPCGHLLCSRCLAAW-----QHSDSQTCPFCR 390
           99********.******************.....6889999****8 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAVAVAPWGR QWEEARALGR AVRMLQRLEE QCSDPRLSLS PPSLRDLLPR TAQLLREVAR 60
AQRAAGRGGP GGPGGSRDFL LVYLANLEAK SRQLGALLPP RGRRSANDEL FRAGSSLRRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGGCCGCAC CGGTCCCTCC CGGCATACGC GAGGCTCCCA TGGCTGTGGC GGTGGCCCCG 60
TGGGGGCGAC AGTGGGAAGA GGCCCGCGCC CTGGGCCGGG CAGTGAGGAT GCTGCAGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0043407--P:negative regulation of MAP kinase activity
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002286	Ailuropoda melanoleuca	79.68	0.00e+00	634.00
IUUC-Bta-012705	Bos taurus	83.06	0.00e+00	662.00
IUUC-Cja-019179	Callithrix jacchus	88.40	0.00e+00	808.00
IUUC-Cfa-020593	Canis familiaris	82.09	1.00e-179	622.00
IUUC-Cpo-021289	Cavia porcellus	76.26	3.00e-174	604.00
IUUC-Csa-023966	Chlorocebus sabaeus	98.90	0.00e+00	804.00
IUUC-Dor-030246	Dipodomys ordii	76.72	5.00e-127	447.00
IUUC-Eca-033921	Equus caballus	71.03	3.00e-150	525.00
IUUC-Fca-035747	Felis catus	65.83	6.00e-156	543.00
IUUC-Ggo-044622	Gorilla gorilla	94.68	0.00e+00	670.00
IUUC-Hsa-045735	Homo sapiens	93.67	0.00e+00	846.00
IUUC-Itr-049001	Ictidomys tridecemlineatus	83.19	2.00e-170	591.00
IUUC-Laf-053983	Loxodonta africana	80.30	0.00e+00	669.00
IUUC-Mmr-061310	Microcebus murinus	80.15	0.00e+00	651.00
IUUC-Mmu-064155	Mus musculus	73.78	0.00e+00	633.00
IUUC-Mpu-066655	Mustela putorius furo	83.54	0.00e+00	655.00
IUUC-Mlu-067929	Myotis lucifugus	83.88	6.00e-154	536.00
IUUC-Nle-070065	Nomascus leucogenys	79.11	0.00e+00	680.00
IUUC-Ocu-074049	Oryctolagus cuniculus	75.76	7.00e-134	469.00
IUUC-Oga-087952	Otolemur garnettii	80.30	0.00e+00	717.00
IUUC-Oar-089382	Ovis aries	80.58	0.00e+00	637.00
IUUC-Ptr-090579	Pan troglodytes	68.99	5.00e-162	563.00
IUUC-Pab-098100	Pongo abelii	84.60	0.00e+00	741.00
IUUC-Pca-100830	Procavia capensis	77.47	3.00e-108	385.00
IUUC-Pva-102714	Pteropus vampyrus	77.78	4.00e-166	577.00
IUUC-Rno-105348	Rattus norvegicus	75.00	0.00e+00	641.00
IUUC-Sha-107138	Sarcophilus harrisii	65.02	7.00e-123	433.00
IUUC-Ssc-116424	Sus scrofa	82.11	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence