iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000008687.1	ENSPSIT00000009725.1	ENSPSIP00000009678.1
ENSPSIG00000008687.1	ENSPSIT00000009735.1	ENSPSIP00000009688.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.50e-07	29.8	78	119

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ f+  p+++pCgH f+  Cl   w    +  ++ f+CP Cr
   Q: 78   CSICLCLFDS-PVTTPCGHNFCGPCLdVTW----SGLQQGFSCPQCR 119
           ********99.*******************....999*********8 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MGESLQPERL AGRGLLGRPP RAELSPFHVI SRNFQLLRLC FEFHFPSPAA QVVAGAMAEL 60
LRAPSLPCLA GLEEELTCSI CLCLFDSPVT TPCGHNFCGP CLDVTWSGLQ QGFSCPQCRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATGGTTTA GGTGGGATTG GTCCTGCTTT TAGCAGCTGA TTGGACTCCA TGACCATCTG 60
AGGTCTCTTC CAACAAACAT TTGAACTATC TCATTACCAA GATAGTTTCC CCAATTATCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000755	Aegilops tauschii	43.24	1.00e-10	60.80
IUUC-Aml-002424	Ailuropoda melanoleuca	50.63	0.00e+00	631.00
IUUC-Apl-004101	Anas platyrhynchos	62.88	0.00e+00	750.00
IUUC-Aca-005025	Anolis carolinensis	62.60	0.00e+00	800.00
IUUC-Bta-012735	Bos taurus	50.31	0.00e+00	653.00
IUUC-Cja-019996	Callithrix jacchus	49.86	2.00e-99	356.00
IUUC-Cfa-020466	Canis familiaris	52.23	0.00e+00	654.00
IUUC-Cpo-021737	Cavia porcellus	47.91	2.00e-175	608.00
IUUC-Csa-023217	Chlorocebus sabaeus	52.95	0.00e+00	654.00
IUUC-Cho-024346	Choloepus hoffmanni	40.61	2.00e-50	192.00
IUUC-Dno-030082	Dasypus novemcinctus	51.10	0.00e+00	642.00
IUUC-Dor-030335	Dipodomys ordii	38.92	2.00e-79	289.00
IUUC-Ete-032923	Echinops telfairi	49.56	1.00e-159	555.00
IUUC-Eca-033411	Equus caballus	52.34	0.00e+00	661.00
IUUC-Eeu-034656	Erinaceus europaeus	52.09	2.00e-102	366.00
IUUC-Fca-035371	Felis catus	50.94	0.00e+00	641.00
IUUC-Fal-037008	Ficedula albicollis	58.02	0.00e+00	707.00
IUUC-Gmo-038668	Gadus morhua	36.60	2.00e-113	402.00
IUUC-Gga-040608	Gallus gallus	60.76	0.00e+00	728.00
IUUC-Gac-041409	Gasterosteus aculeatus	36.66	1.00e-119	423.00
IUUC-Ggo-044518	Gorilla gorilla	51.17	0.00e+00	642.00
IUUC-Hsa-045828	Homo sapiens	52.87	0.00e+00	651.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	49.18	2.00e-169	588.00
IUUC-Lch-050478	Latimeria chalumnae	45.87	3.00e-153	535.00
IUUC-Loc-052864	Lepisosteus oculatus	39.32	4.00e-127	447.00
IUUC-Laf-054325	Loxodonta africana	51.40	2.00e-103	369.00
IUUC-Mcc-054920	Macaca mulatta	52.79	0.00e+00	652.00
IUUC-Meu-056367	Macropus eugenii	67.43	2.00e-72	266.00
IUUC-Mga-059975	Meleagris gallopavo	59.71	0.00e+00	713.00
IUUC-Mmr-060748	Microcebus murinus	49.38	8.00e-178	616.00
IUUC-Mdo-062904	Monodelphis domestica	53.36	0.00e+00	632.00
IUUC-Mmu-063891	Mus musculus	52.38	0.00e+00	649.00
IUUC-Mpu-066473	Mustela putorius furo	51.26	0.00e+00	649.00
IUUC-Mlu-068185	Myotis lucifugus	51.41	0.00e+00	641.00
IUUC-Nle-070177	Nomascus leucogenys	52.31	0.00e+00	657.00
IUUC-Opr-070558	Ochotona princeps	46.48	1.00e-93	336.00
IUUC-Ont-071368	Oreochromis niloticus	36.25	5.00e-112	397.00
IUUC-Ocu-074461	Oryctolagus cuniculus	41.12	2.00e-125	442.00
IUUC-Obr-076219	Oryza brachyantha	41.89	4.00e-10	58.90
IUUC-Ogl-077658	Oryza glaberrima	41.89	2.00e-10	60.10
IUUC-Ogu-078203	Oryza glumaepatula	41.89	2.00e-10	60.10
IUUC-Oin-079383	Oryza indica	41.89	2.00e-10	60.10
IUUC-Ome-081482	Oryza meridionalis	41.89	2.00e-10	60.10
IUUC-Oni-083025	Oryza nivara	41.89	2.00e-10	60.10
IUUC-Opu-083547	Oryza punctata	41.89	2.00e-10	59.70
IUUC-Osa-085978	Oryza sativa	41.89	2.00e-10	60.10
IUUC-Oga-088937	Otolemur garnettii	49.20	1.00e-174	606.00
IUUC-Oar-089781	Ovis aries	48.85	6.00e-123	433.00
IUUC-Ptr-090771	Pan troglodytes	52.31	0.00e+00	644.00
IUUC-Pan-092830	Papio anubis	52.47	0.00e+00	648.00
IUUC-Pfo-096528	Poecilia formosa	36.02	6.00e-120	424.00
IUUC-Pab-097588	Pongo abelii	52.95	0.00e+00	649.00
IUUC-Pca-100890	Procavia capensis	51.37	0.00e+00	629.00
IUUC-Ppe-102024	Prunus persica	41.33	4.00e-10	60.50
IUUC-Pva-102314	Pteropus vampyrus	51.90	1.00e-178	619.00
IUUC-Rno-105234	Rattus norvegicus	50.74	2.00e-96	345.00
IUUC-Sha-106807	Sarcophilus harrisii	49.63	4.00e-178	617.00
IUUC-Sar-113283	Sorex araneus	43.95	6.00e-78	284.00
IUUC-Ssc-115878	Sus scrofa	54.63	4.00e-68	250.00
IUUC-Tgu-117026	Taeniopygia guttata	55.15	4.00e-158	551.00
IUUC-Tru-117794	Takifugu rubripes	35.98	2.00e-109	389.00
IUUC-Tae-123092	Triticum aestivum	43.24	1.00e-10	60.80
IUUC-Tur-126688	Triticum urartu	43.24	1.00e-10	60.10
IUUC-Tbe-127580	Tupaia belangeri	44.85	2.00e-80	291.00
IUUC-Ttr-128648	Tursiops truncatus	45.93	3.00e-119	421.00
IUUC-Vpa-130254	Vicugna pacos	67.61	7.00e-76	277.00
IUUC-Xtr-132892	Xenopus tropicalis	49.86	4.00e-91	327.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence