iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048023

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01070642

Gene Name

SOCS3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000010896.2	ENSSTOT00000010891.2	ENSSTOP00000009768.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	91.91	1.00e-110	396.00	IUUC-Hsa-046909

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MVTHSKFPAA GMSRPLDTSL RLKTFSSKSE YQLVVNAVRK LQESGFYWSA VTGGEANLLL 60
SAEPAGTFLI RDSSDQRHFF TLSVKTQSGT KNLRIQCEGG SFSLQSDPRS TQPVPRFDCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCACCC ACAGCAAGTT TCCCGCCGCC GGGATGAGCC GCCCCCTGGA CACCAGCCTG 60
CGCCTCAAGA CCTTCAGCTC CAAGAGCGAG TACCAGCTGG TGGTGAACGC AGTGCGTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028414--SOCS3
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0060670--P:branching involved in labyrinthine layer morphogenesis
GO:0007259--P:JAK-STAT cascade
GO:0043066--P:negative regulation of apoptotic process
GO:0050728--P:negative regulation of inflammatory response
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0060674--P:placenta blood vessel development
GO:0045597--P:positive regulation of cell differentiation
GO:0016567--P:protein ubiquitination
GO:0060708--P:spongiotrophoblast differentiation
GO:0060707--P:trophoblast giant cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001529	Ailuropoda melanoleuca	90.60	7.00e-105	372.00
IUUC-Apl-003607	Anas platyrhynchos	79.06	3.00e-95	340.00
IUUC-Aca-005063	Anolis carolinensis	78.90	4.00e-102	363.00
IUUC-Ath-006990	Arabidopsis thaliana	32.94	7.00e-03	36.20
IUUC-Ame-010859	Astyanax mexicanus	55.00	4.00e-68	250.00
IUUC-Bta-012817	Bos taurus	92.74	1.00e-110	391.00
IUUC-Bra-017963	Brassica rapa	30.00	4.40e-02	32.70
IUUC-Cja-019605	Callithrix jacchus	90.60	9.00e-111	392.00
IUUC-Cfa-021231	Canis familiaris	91.03	3.00e-106	377.00
IUUC-Cpo-022003	Cavia porcellus	87.61	3.00e-106	377.00
IUUC-Csa-023511	Chlorocebus sabaeus	91.45	3.00e-110	390.00
IUUC-Dre-028536	Danio rerio	56.90	1.00e-72	265.00
IUUC-Dno-029003	Dasypus novemcinctus	86.75	8.00e-108	382.00
IUUC-Eca-034205	Equus caballus	86.96	3.00e-67	246.00
IUUC-Fca-036317	Felis catus	89.66	7.00e-106	375.00
IUUC-Gmo-038777	Gadus morhua	63.89	8.00e-36	142.00
IUUC-Gga-041258	Gallus gallus	80.77	8.00e-96	342.00
IUUC-Gac-041837	Gasterosteus aculeatus	53.78	2.00e-64	237.00
IUUC-Ggo-045620	Gorilla gorilla	91.45	3.00e-110	390.00
IUUC-Hsa-046909	Homo sapiens	91.45	3.00e-110	390.00
IUUC-Lch-049510	Latimeria chalumnae	65.13	8.00e-83	298.00
IUUC-Loc-052863	Lepisosteus oculatus	61.09	2.00e-78	285.00
IUUC-Laf-054136	Loxodonta africana	89.74	4.00e-108	383.00
IUUC-Mcc-055383	Macaca mulatta	91.45	3.00e-110	390.00
IUUC-Meu-056153	Macropus eugenii	85.04	1.00e-107	381.00
IUUC-Mmr-061185	Microcebus murinus	91.03	1.00e-105	375.00
IUUC-Mdo-061819	Monodelphis domestica	85.90	6.00e-110	389.00
IUUC-Mmu-064231	Mus musculus	91.88	2.00e-112	397.00
IUUC-Mpu-066691	Mustela putorius furo	91.03	3.00e-106	377.00
IUUC-Mlu-067673	Myotis lucifugus	87.61	3.00e-111	393.00
IUUC-Ont-072406	Oreochromis niloticus	52.94	3.00e-67	247.00
IUUC-Oan-073249	Ornithorhynchus anatinus	72.65	1.00e-92	331.00
IUUC-Ocu-074935	Oryctolagus cuniculus	88.41	4.00e-32	128.00
IUUC-Ola-087373	Oryzias latipes	46.48	8.00e-47	179.00
IUUC-Oga-088041	Otolemur garnettii	91.88	4.00e-108	383.00
IUUC-Oar-089646	Ovis aries	91.45	2.00e-102	363.00
IUUC-Ptr-091502	Pan troglodytes	91.45	3.00e-110	390.00
IUUC-Pan-091934	Papio anubis	91.45	3.00e-110	390.00
IUUC-Pfo-096412	Poecilia formosa	41.18	2.00e-46	178.00
IUUC-Pab-098554	Pongo abelii	91.45	3.00e-110	390.00
IUUC-Rno-105874	Rattus norvegicus	84.52	3.00e-111	393.00
IUUC-Sha-107151	Sarcophilus harrisii	85.11	2.00e-107	380.00
IUUC-Ssc-115722	Sus scrofa	81.77	1.00e-63	234.00
IUUC-Tgu-117151	Taeniopygia guttata	79.49	5.00e-95	339.00
IUUC-Tru-118428	Takifugu rubripes	52.52	6.00e-67	246.00
IUUC-Tni-120590	Tetraodon nigroviridis	52.52	1.00e-65	241.00
IUUC-Ttr-129065	Tursiops truncatus	94.44	3.00e-110	390.00
IUUC-Xtr-132167	Xenopus tropicalis	63.25	2.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence