iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005085

UUCD1 version

UUC-AnC-00008

Ensembl Protein ID

ENSACAP00000017490.3

UniProt Accession

H9GPM9; H9GPM9_ANOCA

Protein Name

Uncharacterized protein

Gene Name

DDB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000017758.3	ENSACAT00000017835.3	ENSACAP00000017490.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DDB1	0	1799.4	1	1140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DDB1

   S: 2    mldrYvvtarkpsavvklvvgnftshkelNLliaksnrieiflvtpeglrpvvevklegsiavlrlfrpknekkdllfilteryntl 88
           m+ +Yvvta+kp+av+ +v+g+fts+++lNLliak++r+ei++vt+eglrpv+ev ++g+iav++lfrpk+e+kdllfilt++yn++
   Q: 1    MSCNYVVTAQKPTAVNSCVTGHFTSAEDLNLLIAKNTRLEIYVVTAEGLRPVKEVGMYGKIAVMELFRPKGENKDLLFILTAKYNAC 87
           789************************************************************************************ PP
   S: 89   ilelrdidessevvtradgevlDdigrssdsGlinviepkirlialelyqglfklIvldndikelkafnirleelnvsdvkflillt 175
           ile+++++es++++tra+g+v+D+igr+s++G+i++i+p++r+i+l+ly+glfk+I+l++++kelkafnirleel+v+dvkfl++++
   Q: 88   ILEYKQSGESIDIITRAHGNVQDRIGRPSETGIIGIIDPECRMIGLRLYDGLFKVIPLERENKELKAFNIRLEELQVIDVKFLYGCQ 174
           *************************************************************************************** PP
   S: 176  qptgrvlviyqdddgkhlktyelslkdKeFvkis.kqesiekeaellipvpsqlvgvlvlgeesivyksadnykdvdPylirqstai 261
           +pt  ++++yqd++g+h+ktye+sl++KeF+k++ kqe++e+ea+++i+vp++++g++++g+esi+y+++d+y +++P++i+qst++
   Q: 175  APT--ICFVYQDPQGRHVKTYEVSLREKEFNKGPwKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIV 259
           ***..********************************************************************************** PP
   S: 262  ryervdnngirylLgdfdGelkllllsaeeemsG.vevkslkielLgeisiaesisyldngllfvgsrfgdsQlvklisestgkgsy 347
           +++rvd ng+rylLgd++G+l++lll++ee+m+G v +k+l++elLge+siae+++yldng++fvgsr+gdsQlvkl+++s+++gsy
   Q: 260  CHNRVDPNGSRYLLGDMEGRLFMLLLEKEEQMDGgVSLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLNVDSNEQGSY 346
           *************************************************************************************** PP
   S: 348  vvilerfknlkpIvdlvvvdldrrgqgqvvtvsgaskdGslRvirlgigieelasvdlkgvigllslkstidestdnslvlafvset 434
           vv++e+f+nl+pIvd++vvdl+r+gqgq+vt+sga+k+GslR+ir+gigi+e+as+dl+g++gl++l+s+  ++tdn+lvl+fv++t
   Q: 347  VVAMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRSDPHHETDNTLVLSFVGQT 433
           *************************************************************************************** PP
   S: 435  kvlnlntgeeledtelsgvlsdlqtlltqdvidykqllqvTsqsvrLvssqikrllkeWkaknleiigvassNteqvliaatsndlv 521
           +vl+ln gee+e+tel+g+++d+qt+++ +v +++ql+q+Ts+svrLv ++ k+l++eWk++n+++i+vas+N++qv++a+ ++ l+
   Q: 434  RVLMLN-GEEVEETELTGFVDDQQTFFCGNV-AHQQLIQITSASVRLVTQEPKALVSEWKEPNGKNISVASCNSSQVVVAV-GRVLY 517
           ******.************************.************************************************9.***** PP
   S: 522  yleigdgeldltstttlenevavldlinieddpnlsdleavglltdiskrililpdletiykeklggeiipRsilltefEnvtYlLi 608
           ylei+++el+++s t++e+eva+ld+++++d   +s l+a+gl+tdis+ril+lp++++++ke+lggeiipRsil+t+fEn +YlL+
   Q: 518  YLEIHPQELKQISCTEMEHEVACLDITPLGDASGMSPLCAIGLWTDISARILKLPSFDLLHKEMLGGEIIPRSILMTTFENSHYLLC 604
           *************************************************************************************** PP
   S: 609  algdGalvsyildidtgdesdakksnlgtspgtlktfkslsttqvfassDrPtvIyssskkLvfSnVnlkeVqylCsldseaypdsl 695
           algdGal+++ l+i+tg +sd+kk++lgt+p++l+tf+slstt+vfa+sDrPtvIyss++kLvfSnVnlkeV+y+C+l+s++ypdsl
   Q: 605  ALGDGALFYFGLNIETGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSDGYPDSL 691
           *************************************************************************************** PP
   S: 696  alanngslvigtvddiqklkiRsiplgeslrriayqesvitfgvisdrreldf.klklkalrnnasilalvpdiennklfsdglril 781
           alann++l+igt+d+iqkl+iR++pl es+r+i+yqe++++fgv+s+r+e+++ +++++alr++as++al+++++++klfs++++ +
   Q: 692  ALANNSTLTIGTIDEIQKLHIRTVPLSESPRKICYQEVSQCFGVLSSRIEVQDaSGGTTALRPSASTQALSSSVSSSKLFSSSTAPH 778
           *****************************************************9********************************* PP
   S: 782  elseleenevnfllvlDkntfelllaqdlrewEtavsllSqklkdDseeyyvvktalvlpeenelkkgrilvfsvedslklkLltva 868
           e+s++ee+ev++ll++D++tfe+l+a+++ ++E+a+sl+S+kl++D+++y++v+ta+v+p+e+e+k+gri+vf+++d+   kL+tva
   Q: 779  ETSFGEEVEVHNLLIIDQHTFEVLHAHQFLQNEYALSLVSCKLGKDPNTYFIVGTAMVYPDEAEPKQGRIVVFHYSDG---KLQTVA 862
           ******************************************************************************...****** PP
   S: 869  ekkvkgavidlvklNgkllaainseirlyewkvmgtdekelrkeCernntilaLtlktrkdfivVgDlmrsvtLllykdlegsfeEs 955
           ek+vkgav+++v++Ngklla+ins++rlyew    t ekelr+eC+++n+i+aL++kt++dfi+VgDlmrsv Ll+yk +eg+feE+
   Q: 863  EKEVKGAVYSMVEFNGKLLASINSTVRLYEW----TAEKELRTECNHYNNIMALYVKTKGDFILVGDLMRSVLLLAYKPMEGNFEEI 945
           *******************************....**************************************************** PP
   S: 956  ardynlewmsaveilnddiflgaencgNlfvvkkdikagltdeerslleevgefrlgefvevfrfgtlvlqdvgerevnrssevifg 1042
           ard+n++wmsaveil+dd+flgaen++Nlfv++kd +a++tdeer++l+e g f+lgefv+vf++g+lv+q++ge++++++++v+fg
   Q: 946  ARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKD-SAATTDEERQHLQEFGLFHLGEFVNVFCHGSLVMQNLGETSTPTQGSVLFG 1031
           ***********************************.*************************************************** PP
   S: 1043 tengeigvilrlrrellkflrnlestlkkvikrvakieHssyRsFetekrterasgfvdgdLiesilDlsrdkavdilkvl.yekrw 1128
           t+ng+ig++++l+++++++l +++++l+kvik+v+kieHs++RsF+te++te+a+gf+dgdLies+lD+sr+k+++++++l  ++++
   Q: 1032 TVNGMIGLVTSLSESWYNLLLDVQNRLNKVIKSVGKIEHSFWRSFHTERKTEPAT

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSCNYVVTAQ KPTAVNSCVT GHFTSAEDLN LLIAKNTRLE IYVVTAEGLR PVKEVGMYGK 60
IAVMELFRPK GENKDLLFIL TAKYNACILE YKQSGESIDI ITRAHGNVQD RIGRPSETGI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAACCGCAGC GGCCTCGTGA GACTCCCACG CATGCGCCTT AAATCCCGCT CCCCTCTTTG 60
CCAAGGTGGT TTCGGTTCCA CGCATGCGCG TAAAGCCCAC TCTTTGCCTG TCCTCCCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR004871--Cleavage/polyA-sp_fac_asu_C
IPR031297--DDB1
IPR015943--WD40/YVTN_repeat-like_dom
IPR017986--WD40_repeat_dom

Pfam

PF03178--CPSF_A

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0000784--C:nuclear chromosome, telomeric region
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0003684--F:damaged DNA binding
GO:0035518--P:histone H2A monoubiquitination
GO:0051702--P:interaction with symbiont
GO:0043066--P:negative regulation of apoptotic process
GO:0006289--P:nucleotide-excision repair
GO:0046726--P:positive regulation by virus of viral protein levels in host cell
GO:0045070--P:positive regulation of viral genome replication
GO:1902188--P:positive regulation of viral release from host cell
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:1901990--P:regulation of mitotic cell cycle phase transition
GO:0070914--P:UV-damage excision repair
GO:0016055--P:Wnt signaling pathway

KEGG

acs:100567601

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000120	Aegilops tauschii	49.87	0.00e+00	1124.00
IUUC-Aml-002096	Ailuropoda melanoleuca	97.02	0.00e+00	2244.00
IUUC-Atr-002742	Amborella trichopoda	52.80	0.00e+00	1181.00
IUUC-Apl-003624	Anas platyrhynchos	96.44	0.00e+00	2190.00
IUUC-Aly-005857	Arabidopsis lyrata	52.71	0.00e+00	1180.00
IUUC-Ath-006658	Arabidopsis thaliana	52.62	0.00e+00	1178.00
IUUC-Acl-008149	Aspergillus clavatus	27.03	1.00e-104	374.00
IUUC-Afl-008549	Aspergillus flavus	27.83	6.00e-108	385.00
IUUC-Afu-009076	Aspergillus fumigatus	27.11	7.00e-115	408.00
IUUC-Ani-009302	Aspergillus nidulans	26.74	1.00e-90	328.00
IUUC-Ang-009636	Aspergillus niger	28.12	1.00e-82	301.00
IUUC-Aor-010073	Aspergillus oryzae	27.89	9.00e-113	401.00
IUUC-Ate-010422	Aspergillus terreus	27.12	8.00e-106	378.00
IUUC-Ame-011643	Astyanax mexicanus	80.92	0.00e+00	1828.00
IUUC-Bgr-012164	Blumeria graminis	26.06	6.00e-97	348.00
IUUC-Bta-012494	Bos taurus	97.02	0.00e+00	2244.00
IUUC-Bci-013957	Botrytis cinerea	25.83	1.00e-91	331.00
IUUC-Bdi-014186	Brachypodium distachyon	52.36	0.00e+00	1169.00
IUUC-Bol-015922	Brassica oleracea	53.14	0.00e+00	1191.00
IUUC-Bra-017300	Brassica rapa	53.14	0.00e+00	1185.00
IUUC-Cel-018239	Caenorhabditis elegans	36.99	0.00e+00	770.00
IUUC-Cja-019165	Callithrix jacchus	96.93	0.00e+00	2241.00
IUUC-Cfa-020406	Canis familiaris	97.02	0.00e+00	2244.00
IUUC-Cpo-022154	Cavia porcellus	96.67	0.00e+00	2236.00
IUUC-Cre-022557	Chlamydomonas reinhardtii	41.07	0.00e+00	778.00
IUUC-Csa-024061	Chlorocebus sabaeus	96.93	0.00e+00	2241.00
IUUC-Cho-024554	Choloepus hoffmanni	91.10	0.00e+00	924.00
IUUC-Cin-025466	Ciona intestinalis	61.63	0.00e+00	1470.00
IUUC-Csv-026370	Ciona savignyi	60.18	0.00e+00	1306.00
IUUC-Cgl-026595	Colletotrichum gloeosporioides	25.43	1.00e-97	351.00
IUUC-Cme-027342	Cyanidioschyzon merolae	27.65	8.00e-114	405.00
IUUC-Dre-027448	Danio rerio	92.09	0.00e+00	1031.00
IUUC-Dno-029794	Dasypus novemcinctus	96.84	0.00e+00	2107.00
IUUC-Dor-030789	Dipodomys ordii	82.92	0.00e+00	959.00
IUUC-Dse-031491	Dothistroma septosporum	27.55	1.00e-113	404.00
IUUC-Dme-031940	Drosophila melanogaster	60.51	0.00e+00	1364.00
IUUC-Ete-032913	Echinops telfairi	78.74	0.00e+00	838.00
IUUC-Eca-033777	Equus caballus	96.32	0.00e+00	2221.00
IUUC-Eeu-034900	Erinaceus europaeus	94.44	0.00e+00	1092.00
IUUC-Fca-035869	Felis catus	97.02	0.00e+00	2244.00
IUUC-Fal-036777	Ficedula albicollis	96.59	0.00e+00	2232.00
IUUC-Fox-037954	Fusarium oxysporum	26.52	1.00e-104	374.00
IUUC-Fso-038292	Fusarium solani	25.77	5.00e-108	385.00
IUUC-Gmo-038815	Gadus morhua	82.00	0.00e+00	964.00
IUUC-Ggr-039907	Gaeumannomyces graminis	25.70	3.00e-97	350.00
IUUC-Gga-040995	Gallus gallus	96.93	0.00e+00	2244.00
IUUC-Gac-042390	Gasterosteus aculeatus	89.83	0.00e+00	1984.00
IUUC-Gma-042904	Glycine max	52.19	0.00e+00	1136.00
IUUC-Ggo-044891	Gorilla gorilla	96.59	0.00e+00	2235.00
IUUC-Hsa-046709	Homo sapiens	96.93	0.00e+00	2241.00
IUUC-Hvu-047504	Hordeum vulgare	52.10	0.00e+00	1151.00
IUUC-Itr-048678	Ictidomys tridecemlineatus	96.93	0.00e+00	2244.00
IUUC-Lch-050565	Latimeria chalumnae	93.61	0.00e+00	2178.00
IUUC-Lpe-051260	Leersia perrieri	52.53	0.00e+00	1169.00
IUUC-Loc-052091	Lepisosteus oculatus	82.70	0.00e+00	1481.00
IUUC-Lma-053246	Leptosphaeria maculans	25.24	2.00e-102	367.00
IUUC-Laf-053502	Loxodonta africana	96.93	0.00e+00	2244.00
IUUC-Mcc-054802	Macaca mulatta	96.99	0.00e+00	2227.00
IUUC-Meu-056808	Macropus eugenii	94.27	0.00e+00	1424.00
IUUC-Mor-057253	Magnaporthe oryzae	25.91	4.00e-83	303.00
IUUC-Mpo-057562	Magnaporthe poae	25.37	3.00e-96	346.00
IUUC-Mtr-057743	Medicago truncatula	51.66	0.00e+00	1155.00
IUUC-Mla-059154	Melampsora laricipopulina	25.79	3.00e-73	270.00
IUUC-Mga-059824	Meleagris gallopavo	96.55	0.00e+00	2103.00
IUUC-Mvi-060279	Microbotryum violaceum	27.05	1.00e-111	397.00
IUUC-Mmr-061215	Microcebus murinus	96.32	0.00e+00	2224.00
IUUC-Mdo-062028	Monodelphis domestica	95.05	0.00e+00	1847.00
IUUC-Mmu-064327	Mus musculus	96.93	0.00e+00	2242.00
IUUC-Mac-065445	Musa acuminata	52.71	0.00e+00	1150.00
IUUC-Mpu-065814	Mustela putorius furo	93.86	0.00e+00	2150.00
IUUC-Mlu-067136	Myotis lucifugus	96.93	0.00e+00	2238.00
IUUC-Nfi-068355	Neosartorya fischeri	27.11	2.00e-108	387.00
IUUC-Ncr-068620	Neurospora crassa	25.43	9.00e-91	328.00
IUUC-Nle-069566	Nomascus leucogenys	96.82	0.00e+00	2213.00
IUUC-Opr-070915	Ochotona princeps	88.65	0.00e+00	1825.00
IUUC-Ont-071753	Oreochromis niloticus	90.88	0.00e+00	2108.00
IUUC-Oan-073187	Ornithorhynchus anatinus	97.09	0.00e+00	2032.00
IUUC-Ocu-074619	Oryctolagus cuniculus	96.93	0.00e+00	2241.00
IUUC-Oba-075091	Oryza barthii	44.77	0.00e+00	885.00
IUUC-Obr-076425	Oryza brachyantha	52.92	0.00e+00	1170.00
IUUC-Ogu-078794	Oryza glumaepatula	52.80	0.00e+00	1176.00
IUUC-Oin-079725	Oryza indica	52.80	0.00e+00	1162.00
IUUC-Olo-080842	Oryza longistaminata	50.90	0.00e+00	1074.00
IUUC-Ome-081818	Oryza meridionalis	52.88	0.00e+00	1179.00
IUUC-Oni-082879	Oryza nivara	52.10	0.00e+00	1152.00
IUUC-Opu-083361	Oryza punctata	52.11	0.00e+00	1165.00
IUUC-Oru-084781	Oryza rufipogon	52.80	0.00e+00	1176.00
IUUC-Osa-086293	Oryza sativa	52.80	0.00e+00	1176.00
IUUC-Ola-086881	Oryzias latipes	89.77	0.00e+00	2081.00
IUUC-Olu-087674	Ostreococcus lucimarinus	45.45	0.00e+00	957.00
IUUC-Oga-089056	Otolemur garnettii	97.02	0.00e+00	2243.00
IUUC-Oar-089457	Ovis aries	97.15	0.00e+00	2212.00
IUUC-Ptr-091179	Pan troglodytes	96.88	0.00e+00	2208.00
IUUC-Pan-092019	Papio anubis	96.42	0.00e+00	2231.00
IUUC-Psi-093407	Pelodiscus sinensis	97.51	0.00e+00	2218.00
IUUC-Pma-094272	Petromyzon marinus	86.35	0.00e+00	1843.00
IUUC-Pno-094864	Phaeosphaeria nodorum	26.63	3.00e-112	399.00
IUUC-Ppa-095885	Physcomitrella patens	53.18	0.00e+00	1162.00
IUUC-Pfo-096083	Poecilia formosa	90.27	0.00e+00	2086.00
IUUC-Pab-098652	Pongo abelii	92.32	0.00e+00	2094.00
IUUC-Pop-099593	Populus trichocarpa	52.80	0.00e+00	1130.00
IUUC-Pca-100189	Procavia capensis	96.57	0.00e+00	1294.00
IUUC-Ppe-101987	Prunus persica	52.70	0.00e+00	1114.00
IUUC-Pva-102605	Pteropus vampyrus	96.84	0.00e+00	2240.00
IUUC-Pgr-103659	Puccinia graminis	24.46	1.00e-72	268.00
IUUC-Ptt-103884	Puccinia triticina	23.35	3.00e-58	220.00
IUUC-Pte-104233	Pyrenophora teres	26.64	5.00e-114	405.00
IUUC-Pyt-104454	Pyrenophora triticirepentis	26.80	7.00e-112	398.00
IUUC-Rno-106004	Rattus norvegicus	96.93	0.00e+00	2243.00
IUUC-Sha-106726	Sarcophilus harrisii	95.14	0.00e+00	2047.00
IUUC-Sja-107864	Schizosaccharomyces japonicus	23.65	1.00e-75	278.00
IUUC-Spo-108029	Schizosaccharomyces pombe	26.45	2.00e-102	366.00
IUUC-Ssl-108441	Sclerotinia sclerotiorum	25.04	2.00e-83	304.00
IUUC-Smo-108808	Selaginella moellendorffii	52.58	0.00e+00	1206.00
IUUC-Sit-109735	Setaria italica	52.92	0.00e+00	1167.00
IUUC-Sly-111520	Solanum lycopersicum	52.17	0.00e+00	1149.00
IUUC-Sar-113606	Sorex araneus	92.12	3.00e-131	462.00
IUUC-Sbi-114539	Sorghum bicolor	51.95	0.00e+00	1154.00
IUUC-Sre-114936	Sporisorium reilianum	25.37	3.00e-63	237.00
IUUC-Ssc-116038	Sus scrofa	96.84	0.00e+00	2241.00
IUUC-Tgu-117512	Taeniopygia guttata	96.58	0.00e+00	2234.00
IUUC-Tru-117593	Takifugu rubripes	89.31	0.00e+00	2068.00
IUUC-Tsy-119513	Tarsius syrichta	93.84	0.00e+00	1174.00
IUUC-Tni-120551	Tetraodon nigroviridis	84.63	0.00e+00	1689.00
IUUC-Tca-121505	Theobroma cacao	53.15	0.00e+00	1153.00
IUUC-Tre-122136	Trichoderma reesei	26.07	2.00e-103	370.00
IUUC-Tvi-122512	Trichoderma virens	25.20	7.00e-100	358.00
IUUC-Tae-124186	Triticum aestivum	52.01	0.00e+00	1150.00
IUUC-Tur-126451	Triticum urartu	52.39	0.00e+00	1046.00
IUUC-Tme-127057	Tuber melanosporum	29.23	2.00e-112	400.00
IUUC-Ttr-128891	Tursiops truncatus	92.17	0.00e+00	1447.00
IUUC-Uma-129583	Ustilago maydis	25.52	1.00e-54	208.00
IUUC-Vda-129870	Verticillium dahliae	25.22	1.00e-92	334.00
IUUC-Vpa-130117	Vicugna pacos	92.31	0.00e+00	1695.00
IUUC-Vvi-131033	Vitis vinifera	52.14	0.00e+00	1154.00
IUUC-Xtr-131987	Xenopus tropicalis	92.66	0.00e+00	2127.00
IUUC-Xma-134117	Xiphophorus maculatus	88.29	0.00e+00	2036.00
IUUC-Zma-134758	Zea mays	52.88	0.00e+00	1171.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence