iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048879

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01071184

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000015965.2	ENSSTOT00000015970.2	ENSSTOP00000014289.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.60e-14	53.4	1116	1149

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++ +t++   d t+ l+sG+ Dg i +WD+ tg
   Q: 1116 GHSGAITSVYV-DqTMvLASGGQDGAICLWDVLTG 1149
           8********66.446648*************9887 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MTLTERLREK ISQAFYNHGL LCASYPIPII LFTGLCILAC CYPLLKLPLP GTGPVEFSTP 60
VKDYSPPPVD SDRKQGEPCE QPEWYVGAPV AYIQQIFVKS SVSPWHKNLL AVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCACGCGCA GGACGCTGGG CGCACGTGTG GAGGGTGGTG GGCGGGAGGG GAAAGGTGGG 60
AGGTGAGAGG TGAAGGGGCG GGAGTTGCGC GGGCGCCACG CACCGGACCG CGGACCGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR027295--Quinoprotein_ADH-like_fam
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0045540--P:regulation of cholesterol biosynthetic process
GO:0042304--P:regulation of fatty acid biosynthetic process
GO:0001666--P:response to hypoxia
GO:0032868--P:response to insulin
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	95.82	0.00e+00	1105.00
IUUC-Apl-003294	Anas platyrhynchos	76.87	0.00e+00	1719.00
IUUC-Aca-004424	Anolis carolinensis	69.97	0.00e+00	1500.00
IUUC-Bta-013478	Bos taurus	91.48	0.00e+00	2067.00
IUUC-Bol-016061	Brassica oleracea	25.86	8.00e-13	67.80
IUUC-Cel-018160	Caenorhabditis elegans	29.66	2.00e-66	247.00
IUUC-Cja-019123	Callithrix jacchus	90.93	0.00e+00	2061.00
IUUC-Cfa-021082	Canis familiaris	90.85	0.00e+00	2016.00
IUUC-Cpo-022477	Cavia porcellus	84.78	0.00e+00	1896.00
IUUC-Csa-023176	Chlorocebus sabaeus	90.38	0.00e+00	2051.00
IUUC-Cin-025490	Ciona intestinalis	37.46	5.00e-88	318.00
IUUC-Csv-026115	Ciona savignyi	37.05	5.00e-132	465.00
IUUC-Dre-028008	Danio rerio	67.57	0.00e+00	1513.00
IUUC-Dno-028887	Dasypus novemcinctus	90.79	0.00e+00	1210.00
IUUC-Dor-030467	Dipodomys ordii	94.24	0.00e+00	887.00
IUUC-Dme-032087	Drosophila melanogaster	32.99	9.00e-110	391.00
IUUC-Ete-032372	Echinops telfairi	77.13	0.00e+00	1685.00
IUUC-Eca-033896	Equus caballus	92.81	0.00e+00	2144.00
IUUC-Eeu-035099	Erinaceus europaeus	84.73	0.00e+00	1211.00
IUUC-Fca-035616	Felis catus	86.25	0.00e+00	1934.00
IUUC-Fal-037231	Ficedula albicollis	74.31	0.00e+00	1650.00
IUUC-Gmo-039439	Gadus morhua	73.56	0.00e+00	680.00
IUUC-Gac-041516	Gasterosteus aculeatus	66.87	0.00e+00	1503.00
IUUC-Hsa-046674	Homo sapiens	93.12	0.00e+00	2191.00
IUUC-Lch-049689	Latimeria chalumnae	70.54	0.00e+00	1618.00
IUUC-Loc-052417	Lepisosteus oculatus	52.98	4.00e-126	444.00
IUUC-Laf-053795	Loxodonta africana	90.44	0.00e+00	2056.00
IUUC-Mcc-055502	Macaca mulatta	93.51	0.00e+00	2155.00
IUUC-Mga-059805	Meleagris gallopavo	77.46	0.00e+00	1732.00
IUUC-Mmr-060997	Microcebus murinus	92.89	0.00e+00	2155.00
IUUC-Mdo-062940	Monodelphis domestica	81.17	0.00e+00	1798.00
IUUC-Mmu-063255	Mus musculus	91.16	0.00e+00	2095.00
IUUC-Mpu-066158	Mustela putorius furo	92.10	0.00e+00	2082.00
IUUC-Mlu-067201	Myotis lucifugus	87.17	0.00e+00	2006.00
IUUC-Nle-069145	Nomascus leucogenys	94.76	0.00e+00	1372.00
IUUC-Opr-070797	Ochotona princeps	86.85	0.00e+00	1942.00
IUUC-Ont-071553	Oreochromis niloticus	66.51	0.00e+00	1498.00
IUUC-Ocu-074598	Oryctolagus cuniculus	92.42	0.00e+00	2073.00
IUUC-Ola-086650	Oryzias latipes	84.72	4.00e-110	389.00
IUUC-Oar-089287	Ovis aries	86.13	0.00e+00	1114.00
IUUC-Pan-092004	Papio anubis	93.30	0.00e+00	2142.00
IUUC-Psi-093028	Pelodiscus sinensis	72.55	0.00e+00	1522.00
IUUC-Pma-094145	Petromyzon marinus	50.44	0.00e+00	1126.00
IUUC-Pfo-096320	Poecilia formosa	66.74	0.00e+00	1499.00
IUUC-Pab-097862	Pongo abelii	93.59	0.00e+00	2194.00
IUUC-Pca-100862	Procavia capensis	78.16	0.00e+00	1628.00
IUUC-Pva-103050	Pteropus vampyrus	92.00	0.00e+00	1334.00
IUUC-Rno-105852	Rattus norvegicus	91.63	0.00e+00	2117.00
IUUC-Sha-107312	Sarcophilus harrisii	81.16	0.00e+00	1807.00
IUUC-Sar-113311	Sorex araneus	88.87	0.00e+00	833.00
IUUC-Ssc-116356	Sus scrofa	91.72	0.00e+00	2122.00
IUUC-Tgu-116896	Taeniopygia guttata	60.67	6.00e-150	525.00
IUUC-Tru-118197	Takifugu rubripes	67.63	0.00e+00	1509.00
IUUC-Tni-119823	Tetraodon nigroviridis	65.75	0.00e+00	1491.00
IUUC-Ttr-129164	Tursiops truncatus	91.88	0.00e+00	2093.00
IUUC-Xtr-132819	Xenopus tropicalis	68.86	0.00e+00	1602.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence