iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020801

Ensembl Protein ID

ENSCAFP00000015607.3

UniProt Accession

F6Y7U3; F6Y7U3_CANLF

Genbank Protein ID

ENSCAFP00000015607

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03016606

Gene Name

SIK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010596.3	ENSCAFT00000016864.3	ENSCAFP00000015607.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	74.31	0.00e+00	985.00	IUUC-Hsa-046775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MVIMSELSAA PAGSGPGQQK PLRVGFYDVE RTLGKGNFAV VKLARHRVTK TQVAIKIIDK 60
TRLDSSNLEK IYREVQIMKL LNHPHIIKLY QVMETKDMLY IVTEFAKNGE MFDYLTSNGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCAGCGCG GAGCCATGGT GATCATGTCC GAGTTGAGCG CGGCCCCCGC GGGCTCCGGC 60
CCGGGCCAGC AGAAGCCCCT GCGGGTGGGC TTCTACGACG TGGAGCGGAC CCTGGGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR034672--SIK
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0043276--P:anoikis
GO:0055007--P:cardiac muscle cell differentiation
GO:0032870--P:cellular response to hormone stimulus
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0035556--P:intracellular signal transduction
GO:0032792--P:negative regulation of CREB transcription factor activity
GO:0045721--P:negative regulation of gluconeogenesis
GO:0010868--P:negative regulation of triglyceride biosynthetic process
GO:0006468--P:protein phosphorylation
GO:0007346--P:regulation of mitotic cell cycle
GO:0010830--P:regulation of myotube differentiation

KEGG

cfa:487787

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001538	Ailuropoda melanoleuca	47.49	1.00e-125	443.00
IUUC-Aca-004739	Anolis carolinensis	66.96	0.00e+00	942.00
IUUC-Ame-011603	Astyanax mexicanus	65.88	0.00e+00	775.00
IUUC-Cja-019873	Callithrix jacchus	77.22	0.00e+00	1061.00
IUUC-Cpo-022296	Cavia porcellus	81.60	0.00e+00	918.00
IUUC-Csa-023676	Chlorocebus sabaeus	76.90	0.00e+00	1048.00
IUUC-Cho-025021	Choloepus hoffmanni	74.62	4.00e-153	535.00
IUUC-Cin-025762	Ciona intestinalis	62.24	1.00e-124	441.00
IUUC-Csv-026013	Ciona savignyi	59.35	8.00e-121	426.00
IUUC-Dre-028021	Danio rerio	66.31	0.00e+00	767.00
IUUC-Dno-029103	Dasypus novemcinctus	73.87	0.00e+00	768.00
IUUC-Dme-031957	Drosophila melanogaster	64.09	4.00e-130	459.00
IUUC-Ete-033190	Echinops telfairi	79.22	0.00e+00	685.00
IUUC-Eca-033614	Equus caballus	57.83	2.00e-110	394.00
IUUC-Gmo-039423	Gadus morhua	62.48	0.00e+00	745.00
IUUC-Gga-040174	Gallus gallus	67.29	0.00e+00	913.00
IUUC-Gac-041875	Gasterosteus aculeatus	69.81	3.00e-160	558.00
IUUC-Ggo-045090	Gorilla gorilla	76.94	0.00e+00	1053.00
IUUC-Hsa-046775	Homo sapiens	78.24	0.00e+00	1063.00
IUUC-Itr-048715	Ictidomys tridecemlineatus	78.65	0.00e+00	1062.00
IUUC-Lch-049933	Latimeria chalumnae	58.58	0.00e+00	804.00
IUUC-Loc-052048	Lepisosteus oculatus	68.08	0.00e+00	798.00
IUUC-Laf-054466	Loxodonta africana	75.53	0.00e+00	1086.00
IUUC-Mcc-054655	Macaca mulatta	77.16	0.00e+00	1048.00
IUUC-Meu-056705	Macropus eugenii	75.64	0.00e+00	801.00
IUUC-Mmr-061419	Microcebus murinus	77.07	0.00e+00	1058.00
IUUC-Mdo-062854	Monodelphis domestica	68.44	0.00e+00	867.00
IUUC-Mmu-064252	Mus musculus	75.73	0.00e+00	1123.00
IUUC-Nle-069329	Nomascus leucogenys	75.19	0.00e+00	995.00
IUUC-Opr-071101	Ochotona princeps	64.01	0.00e+00	646.00
IUUC-Ont-071887	Oreochromis niloticus	63.42	0.00e+00	724.00
IUUC-Oan-073050	Ornithorhynchus anatinus	77.12	0.00e+00	895.00
IUUC-Oga-088220	Otolemur garnettii	79.31	0.00e+00	1087.00
IUUC-Oar-089420	Ovis aries	74.90	0.00e+00	946.00
IUUC-Ptr-091258	Pan troglodytes	78.12	0.00e+00	1061.00
IUUC-Pan-092031	Papio anubis	77.16	0.00e+00	1049.00
IUUC-Pfo-097451	Poecilia formosa	64.74	0.00e+00	735.00
IUUC-Pab-097806	Pongo abelii	78.12	0.00e+00	1060.00
IUUC-Pva-102182	Pteropus vampyrus	78.14	0.00e+00	775.00
IUUC-Sha-107262	Sarcophilus harrisii	68.97	0.00e+00	957.00
IUUC-Ssc-115584	Sus scrofa	97.18	1.00e-146	511.00
IUUC-Tgu-116973	Taeniopygia guttata	65.84	0.00e+00	902.00
IUUC-Tru-117598	Takifugu rubripes	56.02	7.00e-117	415.00
IUUC-Tsy-119567	Tarsius syrichta	45.61	1.00e-115	410.00
IUUC-Tni-120589	Tetraodon nigroviridis	59.65	6.00e-118	419.00
IUUC-Tbe-127501	Tupaia belangeri	58.38	6.00e-123	435.00
IUUC-Ttr-128365	Tursiops truncatus	79.79	0.00e+00	844.00
IUUC-Xtr-131848	Xenopus tropicalis	55.18	7.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence