iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ttr-128677

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Recombination activating protein 1

Genbank Nucleotide ID

GQ368532

Gene Name

RAG1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTTRG00000014075.1	ENSTTRT00000014073.1	ENSTTRP00000013344.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.98	0.00e+00	811.00	IUUC-Hsa-045964
E3 activity/RING/RING	91.33	0.00e+00	794.00	IUUC-Mmu-064297

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Tursiops truncatus

Protein Sequence
(Fasta)

MAVSLPPTLG LSSAPDELQH PHIKFSDWKF KLFRVRSFEK APENAQGEKQ DSSEGKPSLE 60
QSPAVLDTPG GQKSALTQLA LKPHPKFLKK SHDDRKARDK AMHQANLRHL CRICGNPFKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGTCT CTTTGCCACC CACCCTGGGA CTCAGTTCCG CCCCAGACGA ACTCCAGCAC 60
CCACATATTA AATTTTCAGA TTGGAAATTT AAGCTATTCA GGGTGAGATC CTTTGAAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0233--DNA recombination
KW-0238--DNA-binding
KW-0539--Nucleus

Interpro

IPR024627--RAG1
IPR019485--RAG1_Znf
IPR023336--RAG_nonamer-bd_dom
IPR013087--Znf_C2H2_type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51487--NBD
PS51765--ZF_RAG1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12940--RAG1
PF10426--zf-RAG1

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0004519--F:endonuclease activity
GO:0043565--F:sequence-specific DNA binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0002250--P:adaptive immune response
GO:0010390--P:histone monoubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0045582--P:positive regulation of T cell differentiation
GO:0002331--P:pre-B cell allelic exclusion
GO:0051865--P:protein autoubiquitination
GO:0033077--P:T cell differentiation in thymus
GO:0043029--P:T cell homeostasis
GO:0048538--P:thymus development
GO:0033151--P:V(D)J recombination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001206	Ailuropoda melanoleuca	92.53	0.00e+00	805.00
IUUC-Apl-003271	Anas platyrhynchos	86.27	0.00e+00	748.00
IUUC-Aca-004400	Anolis carolinensis	83.86	0.00e+00	733.00
IUUC-Ame-011295	Astyanax mexicanus	71.53	8.00e-171	594.00
IUUC-Bta-012421	Bos taurus	87.20	0.00e+00	808.00
IUUC-Cja-019891	Callithrix jacchus	94.22	0.00e+00	811.00
IUUC-Cfa-020740	Canis familiaris	88.19	0.00e+00	768.00
IUUC-Cpo-021800	Cavia porcellus	91.08	0.00e+00	791.00
IUUC-Csa-024203	Chlorocebus sabaeus	82.56	0.00e+00	764.00
IUUC-Dre-028416	Danio rerio	70.80	5.00e-171	595.00
IUUC-Dno-029101	Dasypus novemcinctus	92.29	0.00e+00	797.00
IUUC-Dse-031478	Dothistroma septosporum	29.51	2.00e-09	57.40
IUUC-Eca-033385	Equus caballus	87.20	0.00e+00	807.00
IUUC-Fca-036545	Felis catus	91.08	0.00e+00	796.00
IUUC-Fal-037208	Ficedula albicollis	85.30	0.00e+00	743.00
IUUC-Gmo-039622	Gadus morhua	73.20	1.00e-168	587.00
IUUC-Gga-041182	Gallus gallus	84.58	0.00e+00	697.00
IUUC-Gac-041682	Gasterosteus aculeatus	71.57	2.00e-171	596.00
IUUC-Ggo-044510	Gorilla gorilla	93.73	0.00e+00	808.00
IUUC-Hsa-045964	Homo sapiens	93.98	0.00e+00	811.00
IUUC-Itr-048862	Ictidomys tridecemlineatus	93.25	0.00e+00	806.00
IUUC-Lch-050041	Latimeria chalumnae	79.57	0.00e+00	686.00
IUUC-Loc-052464	Lepisosteus oculatus	76.10	0.00e+00	653.00
IUUC-Laf-053544	Loxodonta africana	93.25	0.00e+00	806.00
IUUC-Mcc-054867	Macaca mulatta	93.73	0.00e+00	809.00
IUUC-Meu-055986	Macropus eugenii	67.83	0.00e+00	642.00
IUUC-Mga-059262	Meleagris gallopavo	84.82	0.00e+00	702.00
IUUC-Mdo-062686	Monodelphis domestica	89.16	0.00e+00	772.00
IUUC-Mmu-064297	Mus musculus	91.33	0.00e+00	794.00
IUUC-Mpu-066027	Mustela putorius furo	92.29	0.00e+00	803.00
IUUC-Mlu-067885	Myotis lucifugus	93.49	0.00e+00	807.00
IUUC-Nle-070073	Nomascus leucogenys	94.46	0.00e+00	814.00
IUUC-Ont-071400	Oreochromis niloticus	77.09	4.00e-180	625.00
IUUC-Oan-072920	Ornithorhynchus anatinus	91.38	0.00e+00	736.00
IUUC-Ocu-074616	Oryctolagus cuniculus	93.49	0.00e+00	802.00
IUUC-Ola-086828	Oryzias latipes	72.35	2.00e-180	626.00
IUUC-Oga-088675	Otolemur garnettii	89.59	5.00e-118	416.00
IUUC-Oar-090380	Ovis aries	94.70	0.00e+00	818.00
IUUC-Ptr-090648	Pan troglodytes	93.98	0.00e+00	810.00
IUUC-Pan-092036	Papio anubis	93.73	0.00e+00	809.00
IUUC-Psi-093130	Pelodiscus sinensis	88.67	0.00e+00	768.00
IUUC-Pfo-097273	Poecilia formosa	77.36	3.00e-172	598.00
IUUC-Pca-100134	Procavia capensis	91.33	0.00e+00	791.00
IUUC-Rno-105632	Rattus norvegicus	91.57	0.00e+00	801.00
IUUC-Sha-107238	Sarcophilus harrisii	88.92	0.00e+00	768.00
IUUC-Sar-113591	Sorex araneus	88.37	0.00e+00	722.00
IUUC-Ssc-115720	Sus scrofa	88.08	0.00e+00	818.00
IUUC-Tgu-117030	Taeniopygia guttata	86.19	0.00e+00	719.00
IUUC-Tru-117669	Takifugu rubripes	73.04	2.00e-172	599.00
IUUC-Tsy-119578	Tarsius syrichta	91.57	0.00e+00	794.00
IUUC-Tni-120073	Tetraodon nigroviridis	72.77	1.00e-172	600.00
IUUC-Tbe-128029	Tupaia belangeri	81.24	0.00e+00	737.00
IUUC-Vpa-130346	Vicugna pacos	94.87	0.00e+00	770.00
IUUC-Xtr-132442	Xenopus tropicalis	78.82	2.00e-78	284.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence