iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010831

Ensembl Protein ID

ENSAMXP00000019367.1

UniProt Accession

W5LHQ5; W5LHQ5_ASTMX

Genbank Protein ID

ENSAMXP00000019367

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

APWO01110271

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000018790.1	ENSAMXT00000019367.1	ENSAMXP00000019367.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.50e-15	56.0	57	115

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +++v ++y+y+++++d+L ++kG++++++   e d +W ++++  +g+rG +P nFv kl+
   Q: 57   DNLVVAMYSYQPSHSDDLGFEKGEKMKIL--LEDDPEWYMAESLSTGQRGYIPRNFVGKLN 115
           57899***********************9..99************************9987 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MGNCGSYDSD GEFSYHPDDE LCEHCNCPIP PGNLTQYNDK FPFNSNYTPP PTSPLPDNLV 60
VAMYSYQPSH SDDLGFEKGE KMKILLEDDP EWYMAESLST GQRGYIPRNF VGKLNSMETE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATACATATTT AATAATATGA TACAGTATGT TTGTCCCCAC GTCCTGACAA GGTGCCTAAA 60
CAAACGTGTG TGTGTGTGTG TGTGTGTCTA AGTGTGTGAT GTGCTGATGG TAAAGTGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-028005	Danio rerio	84.28	0.00e+00	749.00
IUUC-Eeu-035004	Erinaceus europaeus	61.82	3.00e-155	541.00
IUUC-Gmo-038984	Gadus morhua	71.36	0.00e+00	679.00
IUUC-Gac-041854	Gasterosteus aculeatus	76.36	0.00e+00	709.00
IUUC-Loc-052222	Lepisosteus oculatus	70.40	2.00e-173	602.00
IUUC-Ont-071711	Oreochromis niloticus	76.36	0.00e+00	684.00
IUUC-Ola-087000	Oryzias latipes	74.61	0.00e+00	679.00
IUUC-Pfo-096542	Poecilia formosa	76.29	0.00e+00	706.00
IUUC-Sar-113235	Sorex araneus	66.38	8.00e-177	613.00
IUUC-Tru-118559	Takifugu rubripes	73.33	0.00e+00	686.00
IUUC-Tni-119928	Tetraodon nigroviridis	65.33	2.00e-167	582.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence