iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069830

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01076233

Gene Name

ZC3H12A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000011545.1	ENSNLET00000014722.1	ENSNLEP00000014033.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
DUB/Other	94.49	0.00e+00	927.00	IUUC-Hsa-046924
UBD/Other/Other	94.49	0.00e+00	927.00	IUUC-Hsa-046924

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MSGPCGEKPV LEASPTMSLW EFEDSHSRQG TPRLAQEPAA EEASAVELQM KVDFFRKLGY 60
SSTEIHSVLQ KLGVQADTNT VLGELVKHGT ATERERQASP DPSPQPLVPR GGGTPKAPNL 120

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Nucleotide Sequence
(Fasta)

ATGAGTGGCC CCTGTGGAGA GAAGCCTGTC CTGGAAGCCA GCCCCACCAT GAGTCTGTGG 60
GAATTTGAGG ACAGCCACAG CCGTCAGGGC ACCCCCAGGC TGGCTCAAGA GCCGGCCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR021869--RNase_Zc3h12_NYN

Pfam

PF11977--RNase_Zc3h12a

Gene Ontology

GO:0005856--C:cytoskeleton
GO:0005654--C:nucleoplasm
GO:0000932--C:P-body
GO:0043234--C:protein complex
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0035198--F:miRNA binding
GO:0003729--F:mRNA binding
GO:0004540--F:ribonuclease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:1990869--P:cellular response to chemokine
GO:0006974--P:cellular response to DNA damage stimulus
GO:0071222--P:cellular response to lipopolysaccharide
GO:1904628--P:cellular response to phorbol 13-acetate 12-myristate
GO:0071356--P:cellular response to tumor necrosis factor
GO:0098586--P:cellular response to virus
GO:0044828--P:negative regulation by host of viral genome replication
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032715--P:negative regulation of interleukin-6 production
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0045019--P:negative regulation of nitric oxide biosynthetic process
GO:1903799--P:negative regulation of production of miRNAs involved in gene silencing by miRNA
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:0045766--P:positive regulation of angiogenesis
GO:0010508--P:positive regulation of autophagy
GO:0010942--P:positive regulation of cell death
GO:0002230--P:positive regulation of defense response to virus by host
GO:0010595--P:positive regulation of endothelial cell migration
GO:0045600--P:positive regulation of fat cell differentiation
GO:0010884--P:positive regulation of lipid storage
GO:2000627--P:positive regulation of miRNA catabolic process
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1900745--P:positive regulation of p38MAPK cascade
GO:1903003--P:positive regulation of protein deubiquitination
GO:0042307--P:positive regulation of protein import into nucleus
GO:2000379--P:positive regulation of reactive oxygen species metabolic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0016579--P:protein deubiquitination
GO:0051259--P:protein oligomerization
GO:0090502--P:RNA phosphodiester bond hydrolysis, endonucleolytic

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002223	Ailuropoda melanoleuca	84.34	0.00e+00	760.00
IUUC-Apl-003631	Anas platyrhynchos	62.09	2.00e-138	485.00
IUUC-Aca-005301	Anolis carolinensis	54.90	2.00e-126	446.00
IUUC-Ate-010342	Aspergillus terreus	31.25	2.10e-01	29.60
IUUC-Ame-010867	Astyanax mexicanus	64.84	1.00e-111	396.00
IUUC-Bta-012505	Bos taurus	83.70	0.00e+00	796.00
IUUC-Cja-019490	Callithrix jacchus	89.65	0.00e+00	864.00
IUUC-Cfa-021149	Canis familiaris	78.63	0.00e+00	734.00
IUUC-Cpo-021301	Cavia porcellus	83.30	0.00e+00	776.00
IUUC-Csa-023367	Chlorocebus sabaeus	94.01	0.00e+00	914.00
IUUC-Cin-025756	Ciona intestinalis	65.33	6.00e-17	80.50
IUUC-Dre-027579	Danio rerio	65.12	8.00e-111	393.00
IUUC-Dno-030064	Dasypus novemcinctus	81.10	0.00e+00	745.00
IUUC-Dor-031093	Dipodomys ordii	74.07	0.00e+00	696.00
IUUC-Ete-032302	Echinops telfairi	83.89	2.00e-125	442.00
IUUC-Eca-033237	Equus caballus	85.76	0.00e+00	829.00
IUUC-Eeu-035130	Erinaceus europaeus	78.89	0.00e+00	639.00
IUUC-Fca-035416	Felis catus	85.08	0.00e+00	772.00
IUUC-Fal-037281	Ficedula albicollis	54.08	1.00e-149	523.00
IUUC-Fso-038424	Fusarium solani	29.03	3.00e-03	35.80
IUUC-Gmo-039204	Gadus morhua	60.80	8.00e-99	353.00
IUUC-Gac-041980	Gasterosteus aculeatus	53.37	1.00e-108	386.00
IUUC-Ggo-044933	Gorilla gorilla	94.82	0.00e+00	914.00
IUUC-Hsa-046924	Homo sapiens	94.49	0.00e+00	920.00
IUUC-Itr-048614	Ictidomys tridecemlineatus	84.14	0.00e+00	807.00
IUUC-Lch-050063	Latimeria chalumnae	54.09	2.00e-153	536.00
IUUC-Loc-051993	Lepisosteus oculatus	49.50	7.00e-134	470.00
IUUC-Laf-053400	Loxodonta africana	84.90	0.00e+00	825.00
IUUC-Mcc-054768	Macaca mulatta	94.51	0.00e+00	909.00
IUUC-Meu-056059	Macropus eugenii	58.27	4.00e-97	348.00
IUUC-Mga-059707	Meleagris gallopavo	54.64	2.00e-154	539.00
IUUC-Mvi-060339	Microbotryum violaceum	36.54	4.80e-02	30.40
IUUC-Mmr-061391	Microcebus murinus	86.31	0.00e+00	833.00
IUUC-Mdo-062040	Monodelphis domestica	64.02	3.00e-180	625.00
IUUC-Mmu-064420	Mus musculus	80.63	0.00e+00	773.00
IUUC-Mpu-066099	Mustela putorius furo	83.53	0.00e+00	748.00
IUUC-Mlu-067979	Myotis lucifugus	82.24	0.00e+00	791.00
IUUC-Opr-071005	Ochotona princeps	84.70	1.00e-179	622.00
IUUC-Ont-072306	Oreochromis niloticus	43.67	6.00e-117	414.00
IUUC-Oan-073138	Ornithorhynchus anatinus	65.57	1.00e-136	479.00
IUUC-Ocu-073908	Oryctolagus cuniculus	84.37	8.00e-169	586.00
IUUC-Ola-087280	Oryzias latipes	63.73	5.00e-106	378.00
IUUC-Oga-088418	Otolemur garnettii	85.98	0.00e+00	808.00
IUUC-Oar-090414	Ovis aries	82.28	2.00e-180	625.00
IUUC-Ptr-091275	Pan troglodytes	94.31	0.00e+00	914.00
IUUC-Pan-092541	Papio anubis	94.68	0.00e+00	889.00
IUUC-Psi-094002	Pelodiscus sinensis	57.41	2.00e-159	555.00
IUUC-Pab-098538	Pongo abelii	95.16	0.00e+00	909.00
IUUC-Pca-100137	Procavia capensis	84.27	0.00e+00	666.00
IUUC-Pva-102367	Pteropus vampyrus	86.92	0.00e+00	677.00
IUUC-Rno-105133	Rattus norvegicus	80.63	0.00e+00	827.00
IUUC-Sha-106603	Sarcophilus harrisii	65.84	2.00e-154	538.00
IUUC-Tgu-117358	Taeniopygia guttata	59.69	5.00e-135	474.00
IUUC-Tru-118112	Takifugu rubripes	46.90	1.00e-111	397.00
IUUC-Tsy-119005	Tarsius syrichta	69.79	3.00e-141	494.00
IUUC-Ttr-129314	Tursiops truncatus	84.81	0.00e+00	837.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence