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Tag Content
UUCD2 ID IUUC-Bta-013578
UUCD1 version UUC-BoT-00728
Ensembl Protein ID ENSBTAP00000003584.5
UniProt Accession E1BKN0; E1BKN0_BOVIN
Genbank Protein ID ENSBTAP00000003584
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID DAAA02046952
Gene Name KMT2B
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSBTAG00000002763.5 ENSBTAT00000003584.5 ENSBTAP00000003584.5
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 7.50e-30 103.0 1245 1298
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrsk 54
           k+C+vCg++g+++k+l+eCe+Cr+++HpaCl++s ++++ ++++  wiC+ C ++
   Q: 1245 KFCHVCGRKGRGSKHLLECERCRHAYHPACLGPS-YPTRATRKRrhWICSACVRC 1298
           58********************************.88888877777******876 PP
   
Organism Bos taurus
Protein Sequence
(Fasta)
MAAAAGGGSC PGPGSARGRF PGRPRGSGGG GGRGGRGNGA ERVRVALRRG GGAAGPGGAE 60
PGEDTALLRL LGLHRGLRRL RRLWAGPRIQ RGRGRGRGRG WGPSRGCLLE EESSDGESDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Bta-013578|E3,PHD|Bos taurus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGGCGG CGGCGGGCGG CGGCAGTTGC CCCGGGCCTG GCTCCGCGCG GGGCCGCTTC 60
CCGGGCCGGC CGCGGGGCTC CGGCGGGGGC GGGGGCCGCG GCGGACGGGG CAACGGGGCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Bta-013578|E3,PHD|Bos taurus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC
SMART

SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation
KEGG bta:785776
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002367 Ailuropoda melanoleuca 93.49 0.00e+00 3159.00
IUUC-Aca-004718 Anolis carolinensis 56.14 0.00e+00 1448.00
IUUC-Ame-011927 Astyanax mexicanus 44.45 0.00e+00 838.00
IUUC-Bdi-014882 Brachypodium distachyon 33.83 9.00e-28 118.00
IUUC-Bra-017422 Brassica rapa 33.98 6.00e-28 119.00
IUUC-Cja-019138 Callithrix jacchus 90.01 0.00e+00 3133.00
IUUC-Cfa-020020 Canis familiaris 95.44 0.00e+00 3162.00
IUUC-Cpo-021552 Cavia porcellus 89.09 0.00e+00 3079.00
IUUC-Csa-024216 Chlorocebus sabaeus 92.39 0.00e+00 3142.00
IUUC-Dre-027440 Danio rerio 48.51 0.00e+00 775.00
IUUC-Dno-029583 Dasypus novemcinctus 93.53 0.00e+00 2960.00
IUUC-Dor-030903 Dipodomys ordii 87.15 0.00e+00 2149.00
IUUC-Dme-032023 Drosophila melanogaster 47.28 3.00e-92 335.00
IUUC-Eca-034026 Equus caballus 96.86 0.00e+00 1886.00
IUUC-Eeu-034687 Erinaceus europaeus 93.67 0.00e+00 1145.00
IUUC-Fca-036311 Felis catus 94.25 0.00e+00 3240.00
IUUC-Gmo-039265 Gadus morhua 44.86 0.00e+00 803.00
IUUC-Gac-042202 Gasterosteus aculeatus 50.63 0.00e+00 736.00
IUUC-Ggo-044791 Gorilla gorilla 93.15 0.00e+00 2037.00
IUUC-Hsa-046988 Homo sapiens 92.07 0.00e+00 3078.00
IUUC-Hvu-047762 Hordeum vulgare 37.31 1.00e-20 94.40
IUUC-Itr-048907 Ictidomys tridecemlineatus 91.32 0.00e+00 3226.00
IUUC-Lpe-051476 Leersia perrieri 31.96 2.00e-24 108.00
IUUC-Loc-052252 Lepisosteus oculatus 53.88 0.00e+00 780.00
IUUC-Laf-053703 Loxodonta africana 92.68 0.00e+00 2120.00
IUUC-Mcc-054782 Macaca mulatta 90.91 0.00e+00 2370.00
IUUC-Meu-056046 Macropus eugenii 79.81 0.00e+00 1865.00
IUUC-Mmr-061316 Microcebus murinus 91.02 0.00e+00 2773.00
IUUC-Mdo-062648 Monodelphis domestica 80.25 0.00e+00 1981.00
IUUC-Mmu-063579 Mus musculus 89.61 0.00e+00 3151.00
IUUC-Mac-064935 Musa acuminata 33.80 4.00e-30 126.00
IUUC-Mpu-066710 Mustela putorius furo 95.40 0.00e+00 3239.00
IUUC-Mlu-067559 Myotis lucifugus 90.60 0.00e+00 2416.00
IUUC-Nle-070085 Nomascus leucogenys 89.35 0.00e+00 2115.00
IUUC-Opr-071148 Ochotona princeps 86.92 0.00e+00 3072.00
IUUC-Ont-071626 Oreochromis niloticus 46.18 0.00e+00 888.00
IUUC-Ocu-074475 Oryctolagus cuniculus 89.71 0.00e+00 3051.00
IUUC-Obr-076458 Oryza brachyantha 34.98 2.00e-28 120.00
IUUC-Ogl-077851 Oryza glaberrima 36.81 2.00e-28 121.00
IUUC-Ogu-078706 Oryza glumaepatula 36.81 1.00e-28 122.00
IUUC-Oin-079802 Oryza indica 31.90 1.00e-23 104.00
IUUC-Osa-085421 Oryza sativa 36.81 2.00e-28 120.00
IUUC-Ola-086609 Oryzias latipes 51.18 0.00e+00 753.00
IUUC-Oga-088140 Otolemur garnettii 92.26 0.00e+00 3148.00
IUUC-Oar-089447 Ovis aries 97.85 0.00e+00 2350.00
IUUC-Ptr-090902 Pan troglodytes 91.98 0.00e+00 3085.00
IUUC-Pan-091930 Papio anubis 92.39 0.00e+00 3143.00
IUUC-Ppa-095221 Physcomitrella patens 36.49 3.00e-31 130.00
IUUC-Pfo-096884 Poecilia formosa 45.33 0.00e+00 879.00
IUUC-Pab-098404 Pongo abelii 92.72 0.00e+00 1727.00
IUUC-Pop-099620 Populus trichocarpa 32.35 7.00e-27 115.00
IUUC-Pca-100949 Procavia capensis 84.35 0.00e+00 1250.00
IUUC-Ppe-101920 Prunus persica 33.01 4.00e-28 120.00
IUUC-Pva-102634 Pteropus vampyrus 93.89 0.00e+00 3286.00
IUUC-Rno-105870 Rattus norvegicus 89.36 0.00e+00 3207.00
IUUC-Sit-110552 Setaria italica 34.83 4.00e-29 123.00
IUUC-Sar-113289 Sorex araneus 90.03 0.00e+00 1727.00
IUUC-Ssc-115509 Sus scrofa 95.53 0.00e+00 3309.00
IUUC-Tru-117736 Takifugu rubripes 45.18 0.00e+00 828.00
IUUC-Tca-121624 Theobroma cacao 32.68 3.00e-28 120.00
IUUC-Tae-124647 Triticum aestivum 37.31 1.00e-20 94.70
IUUC-Tbe-127825 Tupaia belangeri 88.67 0.00e+00 1441.00
IUUC-Ttr-128754 Tursiops truncatus 94.81 0.00e+00 1262.00
IUUC-Xtr-132838 Xenopus tropicalis 48.87 0.00e+00 986.00
IUUC-Xma-133119 Xiphophorus maculatus 43.07 0.00e+00 951.00
Created Date 25-Jun-2017

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