iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037202

Ensembl Protein ID

ENSFALP00000004262.1

UniProt Accession

U3JNA8; U3JNA8_FICAL

Genbank Protein ID

ENSFALP00000004262

Protein Name

Coatomer subunit beta'

Genbank Nucleotide ID

AGTO01011577

Gene Name

COPB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000004094.1	ENSFALT00000004283.1	ENSFALP00000004262.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-33	111.9	154	195
UBD/Beta-Prp	3.70e-68	229.5	2	263

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+ +v+c+++    d ++l+sG+dD  +k+WD+   +++++
   Q: 154  GHEKGVNCIDYysgGDkPYLISGADDRLVKIWDYQNKTCVQT 195
           8*********9999778****************999988875 PP

UBD/Beta-Prp

   S: 26   atgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGsh 114
           +++ ++g++ vw+ +t++l++ ++ ++ +v+a kf  ++++ vtg++D+ i+v++++t + vh +++h+d++++++++p++ ++++ s+
   Q: 2    LASLYNGSVCVWNHETQTLVKNFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSD 90
           67889************************************************************************************ PP
   S: 115  drtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsl 200
           d  i++wd+++++  +++++gh++ v+ +v++p++ n ++s+slDrt+++W+l + +   tl+g h++ v+++++ s g  ++l+sg++
   Q: 91   DMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDnNQFASASLDRTIKVWQLGSSSPNFTLEG-HEKGVNCIDYYSGGdkPYLISGAD 178
           *************9999**********************************************9.*********8887777******** PP
   S: 201  dgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgse 285
           d+ vk+wd+q+++cv+tl+gh +nv++v f+p+  ++++gs+Dg++riW + +  l +tl++  ++v++va l+ ++nv +  +e
   Q: 179  DRLVKIWDYQNKTCVQTLEGHAQNVSCVSFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDE 263
           ************************************************************************9999998755544 PP

Organism

Ficedula albicollis

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MLASLYNGSV CVWNHETQTL VKNFEVCDLP VRAAKFVARK NWVVTGADDM QIRVFNYNTL 60
ERVHMFEAHS DYIRCIAVHP TQPFILTSSD DMLIKLWDWD KKWSCSQVFE GHTHYVMQIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGATGTG CAGTGCATCT CTTTTGTTTT TTCTTTGACT CTGCTGGAGA TACTTTTTGC 60
AGTATGAAGA AATTCTGACT TTCACAGGAT TAAATTAAAC AGAGCAATTG CCGTTGGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011044--Quino_amine_DH_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:1901998--P:toxin transport

KEGG

fab:101809137

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000654	Aegilops tauschii	56.15	0.00e+00	916.00
IUUC-Aml-002154	Ailuropoda melanoleuca	92.99	0.00e+00	1682.00
IUUC-Atr-003090	Amborella trichopoda	58.06	0.00e+00	1029.00
IUUC-Apl-003976	Anas platyrhynchos	98.36	0.00e+00	1754.00
IUUC-Aca-004301	Anolis carolinensis	98.04	0.00e+00	1674.00
IUUC-Aly-005643	Arabidopsis lyrata	59.95	0.00e+00	1048.00
IUUC-Ath-007630	Arabidopsis thaliana	60.93	0.00e+00	1055.00
IUUC-Ago-007914	Ashbya gossypii	46.25	0.00e+00	722.00
IUUC-Acl-008237	Aspergillus clavatus	55.88	0.00e+00	921.00
IUUC-Afl-008535	Aspergillus flavus	55.69	0.00e+00	913.00
IUUC-Afu-008845	Aspergillus fumigatus	53.71	0.00e+00	897.00
IUUC-Ani-009135	Aspergillus nidulans	55.17	0.00e+00	869.00
IUUC-Ang-009654	Aspergillus niger	55.75	0.00e+00	818.00
IUUC-Aor-009939	Aspergillus oryzae	53.53	0.00e+00	925.00
IUUC-Ate-010355	Aspergillus terreus	54.09	0.00e+00	872.00
IUUC-Ame-010922	Astyanax mexicanus	82.05	0.00e+00	1459.00
IUUC-Bgr-012249	Blumeria graminis	53.33	0.00e+00	908.00
IUUC-Bta-013579	Bos taurus	98.32	0.00e+00	1474.00
IUUC-Bci-013866	Botrytis cinerea	55.29	0.00e+00	891.00
IUUC-Bdi-015046	Brachypodium distachyon	60.49	0.00e+00	1062.00
IUUC-Bol-015731	Brassica oleracea	59.95	0.00e+00	1065.00
IUUC-Bra-017758	Brassica rapa	59.93	0.00e+00	1065.00
IUUC-Cel-018387	Caenorhabditis elegans	66.50	0.00e+00	1137.00
IUUC-Cja-019145	Callithrix jacchus	93.21	0.00e+00	1683.00
IUUC-Cfa-020564	Canis familiaris	93.21	0.00e+00	1677.00
IUUC-Cpo-022201	Cavia porcellus	95.68	0.00e+00	1672.00
IUUC-Cre-022938	Chlamydomonas reinhardtii	58.29	0.00e+00	942.00
IUUC-Csa-023383	Chlorocebus sabaeus	97.40	0.00e+00	1112.00
IUUC-Cho-024454	Choloepus hoffmanni	91.23	0.00e+00	1338.00
IUUC-Cin-025681	Ciona intestinalis	76.22	0.00e+00	1325.00
IUUC-Csv-026012	Ciona savignyi	76.71	0.00e+00	1297.00
IUUC-Cgl-026649	Colletotrichum gloeosporioides	52.50	0.00e+00	807.00
IUUC-Cne-026986	Cryptococcus neoformans	50.56	0.00e+00	874.00
IUUC-Cme-027219	Cyanidioschyzon merolae	47.92	0.00e+00	824.00
IUUC-Dre-027846	Danio rerio	93.41	0.00e+00	1645.00
IUUC-Dor-030462	Dipodomys ordii	91.82	0.00e+00	1205.00
IUUC-Dse-031268	Dothistroma septosporum	54.79	0.00e+00	909.00
IUUC-Dme-031791	Drosophila melanogaster	70.90	0.00e+00	1222.00
IUUC-Ete-033166	Echinops telfairi	87.15	0.00e+00	946.00
IUUC-Eca-034180	Equus caballus	92.93	0.00e+00	1615.00
IUUC-Eeu-035086	Erinaceus europaeus	81.24	0.00e+00	843.00
IUUC-Fca-036265	Felis catus	92.99	0.00e+00	1682.00
IUUC-Fox-037711	Fusarium oxysporum	56.67	0.00e+00	848.00
IUUC-Fso-038268	Fusarium solani	56.19	0.00e+00	847.00
IUUC-Gmo-039046	Gadus morhua	93.87	0.00e+00	1618.00
IUUC-Ggr-039863	Gaeumannomyces graminis	55.26	0.00e+00	864.00
IUUC-Gga-041112	Gallus gallus	98.01	0.00e+00	1748.00
IUUC-Gac-041733	Gasterosteus aculeatus	93.89	0.00e+00	1581.00
IUUC-Gma-044333	Glycine max	61.86	0.00e+00	1068.00
IUUC-Ggo-044984	Gorilla gorilla	92.65	0.00e+00	1676.00
IUUC-Hsa-046698	Homo sapiens	92.65	0.00e+00	1676.00
IUUC-Hvu-047669	Hordeum vulgare	69.94	3.00e-154	537.00
IUUC-Itr-048212	Ictidomys tridecemlineatus	93.10	0.00e+00	1672.00
IUUC-Kpa-049265	Komagataella pastoris	48.58	0.00e+00	819.00
IUUC-Lch-050473	Latimeria chalumnae	91.91	0.00e+00	1684.00
IUUC-Lpe-051579	Leersia perrieri	60.66	0.00e+00	1066.00
IUUC-Loc-052675	Lepisosteus oculatus	94.35	0.00e+00	1657.00
IUUC-Lma-053218	Leptosphaeria maculans	54.43	0.00e+00	888.00
IUUC-Laf-053757	Loxodonta africana	92.78	0.00e+00	1674.00
IUUC-Mcc-054859	Macaca mulatta	93.10	0.00e+00	1681.00
IUUC-Meu-056174	Macropus eugenii	95.29	0.00e+00	751.00
IUUC-Mor-057264	Magnaporthe oryzae	55.57	0.00e+00	847.00
IUUC-Mpo-057538	Magnaporthe poae	55.64	0.00e+00	879.00
IUUC-Mtr-058310	Medicago truncatula	61.86	0.00e+00	1078.00
IUUC-Mla-058937	Melampsora laricipopulina	53.65	0.00e+00	872.00
IUUC-Mga-059875	Meleagris gallopavo	97.78	0.00e+00	1742.00
IUUC-Mvi-060240	Microbotryum violaceum	50.26	0.00e+00	865.00
IUUC-Mmr-061261	Microcebus murinus	93.55	0.00e+00	1689.00
IUUC-Mdo-062076	Monodelphis domestica	94.61	0.00e+00	1691.00
IUUC-Mmu-063324	Mus musculus	93.10	0.00e+00	1683.00
IUUC-Mac-064636	Musa acuminata	59.27	0.00e+00	1035.00
IUUC-Mpu-065961	Mustela putorius furo	93.44	0.00e+00	1682.00
IUUC-Mlu-067059	Myotis lucifugus	95.08	0.00e+00	1616.00
IUUC-Nfi-068277	Neosartorya fischeri	54.27	0.00e+00	892.00
IUUC-Ncr-068659	Neurospora crassa	52.10	0.00e+00	867.00
IUUC-Nle-069034	Nomascus leucogenys	92.99	0.00e+00	1681.00
IUUC-Opr-070334	Ochotona princeps	97.60	0.00e+00	1451.00
IUUC-Ont-071563	Oreochromis niloticus	94.25	0.00e+00	1631.00
IUUC-Oan-073416	Ornithorhynchus anatinus	97.32	0.00e+00	1658.00
IUUC-Ocu-074522	Oryctolagus cuniculus	93.21	0.00e+00	1680.00
IUUC-Oba-075760	Oryza barthii	60.15	0.00e+00	1066.00
IUUC-Obr-076201	Oryza brachyantha	60.37	0.00e+00	1055.00
IUUC-Ogl-077450	Oryza glaberrima	60.15	0.00e+00	1060.00
IUUC-Ogu-078994	Oryza glumaepatula	60.98	0.00e+00	1064.00
IUUC-Oin-079211	Oryza indica	60.15	0.00e+00	1063.00
IUUC-Olo-080731	Oryza longistaminata	60.15	0.00e+00	1063.00
IUUC-Ome-081762	Oryza meridionalis	57.58	0.00e+00	999.00
IUUC-Oni-082324	Oryza nivara	60.15	0.00e+00	1064.00
IUUC-Opu-083400	Oryza punctata	58.33	0.00e+00	1037.00
IUUC-Oru-084829	Oryza rufipogon	60.15	0.00e+00	1064.00
IUUC-Osa-086026	Oryza sativa	60.98	0.00e+00	1063.00
IUUC-Ola-087245	Oryzias latipes	92.79	0.00e+00	1630.00
IUUC-Olu-087655	Ostreococcus lucimarinus	59.38	0.00e+00	1006.00
IUUC-Oga-088163	Otolemur garnettii	89.84	0.00e+00	1611.00
IUUC-Oar-089842	Ovis aries	95.56	0.00e+00	1670.00
IUUC-Ptr-090501	Pan troglodytes	92.87	0.00e+00	1679.00
IUUC-Pan-092011	Papio anubis	93.10	0.00e+00	1682.00
IUUC-Psi-093308	Pelodiscus sinensis	95.67	0.00e+00	1689.00
IUUC-Pma-094695	Petromyzon marinus	80.84	0.00e+00	1394.00
IUUC-Pno-094785	Phaeosphaeria nodorum	62.07	2.00e-112	399.00
IUUC-Ppa-095911	Physcomitrella patens	61.29	0.00e+00	1082.00
IUUC-Pfo-096587	Poecilia formosa	92.11	0.00e+00	1633.00
IUUC-Pab-097926	Pongo abelii	90.34	0.00e+00	1585.00
IUUC-Pop-099634	Populus trichocarpa	61.10	0.00e+00	1055.00
IUUC-Pca-100965	Procavia capensis	91.63	0.00e+00	1637.00
IUUC-Ppe-101470	Prunus persica	61.73	0.00e+00	1068.00
IUUC-Pva-102451	Pteropus vampyrus	90.88	0.00e+00	1196.00
IUUC-Pgr-103590	Puccinia graminis	53.15	0.00e+00	885.00
IUUC-Ptt-103868	Puccinia triticina	53.15	0.00e+00	884.00
IUUC-Pte-104274	Pyrenophora teres	54.85	0.00e+00	910.00
IUUC-Pyt-104794	Pyrenophora triticirepentis	54.83	0.00e+00	905.00
IUUC-Rno-105979	Rattus norvegicus	83.22	0.00e+00	1198.00
IUUC-Sce-106269	Saccharomyces cerevisiae	46.88	0.00e+00	742.00
IUUC-Sha-106905	Sarcophilus harrisii	96.52	0.00e+00	1688.00
IUUC-Sja-107838	Schizosaccharomyces japonicus	46.79	0.00e+00	791.00
IUUC-Spo-108299	Schizosaccharomyces pombe	46.73	0.00e+00	791.00
IUUC-Smo-108695	Selaginella moellendorffii	61.49	0.00e+00	1045.00
IUUC-Sit-110340	Setaria italica	59.24	0.00e+00	1071.00
IUUC-Sly-111775	Solanum lycopersicum	57.73	0.00e+00	1049.00
IUUC-Stu-112906	Solanum tuberosum	60.30	0.00e+00	997.00
IUUC-Sar-113472	Sorex araneus	90.13	0.00e+00	1148.00
IUUC-Sbi-114052	Sorghum bicolor	62.61	0.00e+00	1069.00
IUUC-Sre-115040	Sporisorium reilianum	51.89	0.00e+00	873.00
IUUC-Ssc-115593	Sus scrofa	93.55	0.00e+00	1687.00
IUUC-Tgu-117239	Taeniopygia guttata	99.53	0.00e+00	1773.00
IUUC-Tru-118025	Takifugu rubripes	94.26	0.00e+00	1625.00
IUUC-Tsy-118824	Tarsius syrichta	89.32	0.00e+00	1099.00
IUUC-Tni-120142	Tetraodon nigroviridis	92.22	0.00e+00	1626.00
IUUC-Tca-121613	Theobroma cacao	60.85	0.00e+00	1057.00
IUUC-Tre-122072	Trichoderma reesei	55.20	0.00e+00	893.00
IUUC-Tvi-122546	Trichoderma virens	54.69	0.00e+00	879.00
IUUC-Tae-125292	Triticum aestivum	60.73	0.00e+00	1053.00
IUUC-Tur-126283	Triticum urartu	55.18	0.00e+00	909.00
IUUC-Tme-127041	Tuber melanosporum	56.44	0.00e+00	936.00
IUUC-Tbe-127770	Tupaia belangeri	91.04	0.00e+00	1204.00
IUUC-Ttr-129294	Tursiops truncatus	93.11	0.00e+00	1681.00
IUUC-Uma-129351	Ustilago maydis	50.25	0.00e+00	861.00
IUUC-Vda-129716	Verticillium dahliae	55.33	0.00e+00	914.00
IUUC-Vpa-130037	Vicugna pacos	82.40	0.00e+00	872.00
IUUC-Vvi-131689	Vitis vinifera	60.17	0.00e+00	1066.00
IUUC-Xtr-132633	Xenopus tropicalis	92.35	0.00e+00	1637.00
IUUC-Xma-133347	Xiphophorus maculatus	94.01	0.00e+00	1634.00
IUUC-Yli-134455	Yarrowia lipolytica	50.20	0.00e+00	803.00
IUUC-Zma-135706	Zea mays	59.88	0.00e+00	1077.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence