iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028136

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 35

Genbank Nucleotide ID

CU469093

Gene Name

klhl35; si:ch73-211p17.3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000063577.6	ENSDART00000093028.5	ENSDARP00000087460.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-18	68.1	41	108
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-08	33.6	109	134

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+l v+g ef++h+++L+asS +F+ +f +++ es+ +  v+++dv+  +++ ll+F+Y g+l+++e
   Q: 41   TDVVLLVDGCEFPCHRATLCASSGFFRTMFGSHFTESR-QAAVTLQDVSRAAMEKLLDFMYEGRLTLDE 108
           7*************************************.**************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfi 27
           eN+ +++++Ad++d p L++a++ f+
   Q: 109  ENVQSVFQAADRLDVPVLYKACVQFL 134
           8***********************97 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MGFGSSGELM DRSNVSFCSG SCHAEHILQV LNSYRRSGTF TDVVLLVDGC EFPCHRATLC 60
ASSGFFRTMF GSHFTESRQA AVTLQDVSRA AMEKLLDFMY EGRLTLDEEN VQSVFQAADR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGATTGAC ACAATCAAAT ATAAGAGAAC TCGGGAGACA GGGAAGCGGA GTTCATGCGA 60
ACAGAGGAGA TGACGCGCTG GAGCCCCGCC CACATTACAC TGAAGCCCCG CCTCCTACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030601--KLHL35
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

dre:570873

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008230	Aspergillus clavatus	29.41	2.00e-09	56.20
IUUC-Ani-009467	Aspergillus nidulans	28.05	2.00e-08	53.50
IUUC-Ame-010747	Astyanax mexicanus	63.25	0.00e+00	637.00
IUUC-Fso-038419	Fusarium solani	36.78	2.00e-07	50.10
IUUC-Loc-052921	Lepisosteus oculatus	56.22	0.00e+00	636.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence