iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000004378.11	ENSDART00000136695.2	ENSDARP00000122444.1
ENSDARG00000004378.11	ENSDART00000148287.2	ENSDARP00000121344.1
ENSDARG00000004378.11	ENSDART00000151433.1	ENSDARP00000125669.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.00e-16	59.1	77	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++++ly+y+a ++d+L+++kG++ ++i  ++++++W+++ + ++gk+G +P+n+v+ ++
   Q: 77   LFIALYEYDARTEDDLSFQKGEKFHII--NNTEGDWWEARSLDTGKSGYIPSNYVAPVD 133
           5789***********************..8999**********************9987 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MGCACCKQRK ASKAVSNQNS CDAFNGTQAS EPSRYIPDPT FNSGIPNFND FSNPLTPPTS 60
IINPARPPGL TGGGVTLFIA LYEYDARTED DLSFQKGEKF HIINNTEGDW WEARSLDTGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCTGAAG CAGCGCATCG CGGCCGGTTG ATCGCCGCTC GGACACTCAA GCTCCGCCAC 60
CCTGCCTCCT CCAGCGACAT TAACTAAGGT AAGTTATTTC TGACTTTCTT TTATTTAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0045087--P:innate immune response
GO:0007229--P:integrin-mediated signaling pathway
GO:0048246--P:macrophage chemotaxis
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011816	Astyanax mexicanus	88.91	0.00e+00	976.00
IUUC-Cel-018594	Caenorhabditis elegans	56.14	9.00e-148	517.00
IUUC-Fal-036786	Ficedula albicollis	85.80	0.00e+00	887.00
IUUC-Gga-040762	Gallus gallus	81.30	0.00e+00	895.00
IUUC-Gac-041918	Gasterosteus aculeatus	89.92	0.00e+00	920.00
IUUC-Loc-052620	Lepisosteus oculatus	84.59	0.00e+00	934.00
IUUC-Ont-072409	Oreochromis niloticus	85.39	0.00e+00	880.00
IUUC-Ogl-077331	Oryza glaberrima	34.65	2.00e-23	104.00
IUUC-Ogu-078962	Oryza glumaepatula	34.65	2.00e-23	104.00
IUUC-Oin-079172	Oryza indica	34.65	1.00e-23	105.00
IUUC-Olo-080286	Oryza longistaminata	34.65	2.00e-23	105.00
IUUC-Ome-081400	Oryza meridionalis	34.65	1.00e-23	105.00
IUUC-Oru-084741	Oryza rufipogon	34.65	1.00e-23	105.00
IUUC-Osa-085779	Oryza sativa	34.62	1.00e-23	105.00
IUUC-Ola-086657	Oryzias latipes	90.22	0.00e+00	932.00
IUUC-Tru-117916	Takifugu rubripes	87.65	0.00e+00	905.00
IUUC-Tni-120886	Tetraodon nigroviridis	84.55	0.00e+00	939.00
IUUC-Tae-123192	Triticum aestivum	30.16	3.00e-21	97.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence