iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011919

Ensembl Protein ID

ENSAMXP00000018123.1

UniProt Accession

W5LE61; W5LE61_ASTMX

Genbank Protein ID

ENSAMXP00000018123

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01016929

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000017521.1	ENSAMXT00000018123.1	ENSAMXP00000018123.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	56.20	2.00e-122	437.00	IUUC-Cel-018674
E3 activity/RING/RING	64.91	0.00e+00	1050.00	IUUC-Hsa-046306
UBD/Alpha-Helix/UBA	64.91	0.00e+00	1050.00	IUUC-Hsa-046306
UBD/Alpha-Helix/UBA	64.01	0.00e+00	1016.00	IUUC-Mmu-063114

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MATALSGRGL GGRTQNQRKG RILGFIDAIQ DVVGPPKQAA ADRRTVEKTW KLMDKVVRLC 60
QNPRLQLKNS PPYILDILPD TYQHLRMILC KYEENQKLVQ LSENDYFKVY IDSLMKKSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGTGTCTG TGGGCGGGGC GGGACGCAGC CCCGGTCTCT GTGCTGCGCT GAGCTCTGCT 60
CTCCTCCACG GCTTTTAAAC GCGTACTGAT TTAGAAACGA GCCAACGAGC TGCAGATCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR024162--Adaptor_Cbl
IPR014741--Adaptor_Cbl_EF_hand-like
IPR003153--Adaptor_Cbl_N_hlx
IPR014742--Adaptor_Cbl_SH2-like
IPR024159--Cbl_PTB
IPR011992--EF-hand-dom_pair
IPR000980--SH2
IPR015940--UBA
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51506--CBL_PTB
PS50030--UBA
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02262--Cbl_N
PF02761--Cbl_N2
PF02762--Cbl_N3

SMART

SM00184--RING
SM00165--UBA

Gene Ontology

GO:0005634--C:nucleus
GO:0005509--F:calcium ion binding
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007166--P:cell surface receptor signaling pathway
GO:0023051--P:regulation of signaling

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001412	Ailuropoda melanoleuca	64.89	0.00e+00	1015.00
IUUC-Apl-004148	Anas platyrhynchos	64.54	0.00e+00	1043.00
IUUC-Aca-005204	Anolis carolinensis	63.87	0.00e+00	991.00
IUUC-Bta-013044	Bos taurus	63.96	0.00e+00	1006.00
IUUC-Cel-018674	Caenorhabditis elegans	56.20	9.00e-124	437.00
IUUC-Cja-018813	Callithrix jacchus	79.01	0.00e+00	828.00
IUUC-Cfa-021054	Canis familiaris	64.99	0.00e+00	1055.00
IUUC-Cpo-022514	Cavia porcellus	63.57	0.00e+00	1023.00
IUUC-Csa-024110	Chlorocebus sabaeus	64.85	0.00e+00	1039.00
IUUC-Cho-024886	Choloepus hoffmanni	51.41	5.00e-180	624.00
IUUC-Cin-025574	Ciona intestinalis	65.70	8.00e-166	576.00
IUUC-Csv-025938	Ciona savignyi	68.27	5.00e-158	550.00
IUUC-Dre-027480	Danio rerio	74.19	0.00e+00	1246.00
IUUC-Dno-028923	Dasypus novemcinctus	64.78	0.00e+00	1005.00
IUUC-Dor-031040	Dipodomys ordii	92.56	0.00e+00	665.00
IUUC-Dme-032213	Drosophila melanogaster	67.42	1.00e-168	587.00
IUUC-Ete-032406	Echinops telfairi	62.45	0.00e+00	928.00
IUUC-Eca-033849	Equus caballus	64.58	0.00e+00	1034.00
IUUC-Eeu-035142	Erinaceus europaeus	70.95	9.00e-150	523.00
IUUC-Fca-036224	Felis catus	64.62	0.00e+00	1033.00
IUUC-Fal-036860	Ficedula albicollis	79.74	0.00e+00	848.00
IUUC-Gmo-038698	Gadus morhua	84.38	0.00e+00	666.00
IUUC-Gga-040159	Gallus gallus	64.18	0.00e+00	1030.00
IUUC-Gac-042312	Gasterosteus aculeatus	77.43	0.00e+00	804.00
IUUC-Ggo-045175	Gorilla gorilla	61.48	0.00e+00	989.00
IUUC-Hsa-046306	Homo sapiens	64.98	0.00e+00	1037.00
IUUC-Loc-052524	Lepisosteus oculatus	71.54	0.00e+00	1136.00
IUUC-Laf-053635	Loxodonta africana	61.03	0.00e+00	949.00
IUUC-Mcc-055536	Macaca mulatta	64.75	0.00e+00	1038.00
IUUC-Meu-056045	Macropus eugenii	55.68	0.00e+00	707.00
IUUC-Mga-060177	Meleagris gallopavo	72.18	0.00e+00	810.00
IUUC-Mmr-061088	Microcebus murinus	64.72	0.00e+00	1035.00
IUUC-Mdo-062020	Monodelphis domestica	64.50	0.00e+00	1014.00
IUUC-Mmu-063114	Mus musculus	64.16	0.00e+00	1007.00
IUUC-Mpu-066632	Mustela putorius furo	64.78	0.00e+00	1049.00
IUUC-Mlu-067145	Myotis lucifugus	64.74	0.00e+00	1029.00
IUUC-Nle-069285	Nomascus leucogenys	83.47	0.00e+00	674.00
IUUC-Ont-072323	Oreochromis niloticus	66.89	0.00e+00	905.00
IUUC-Oan-073165	Ornithorhynchus anatinus	64.33	0.00e+00	1042.00
IUUC-Ocu-074723	Oryctolagus cuniculus	64.89	0.00e+00	1040.00
IUUC-Oga-088021	Otolemur garnettii	63.93	0.00e+00	1021.00
IUUC-Oar-089809	Ovis aries	64.58	0.00e+00	1012.00
IUUC-Ptr-090834	Pan troglodytes	64.98	0.00e+00	1037.00
IUUC-Pan-092225	Papio anubis	64.75	0.00e+00	1038.00
IUUC-Psi-093317	Pelodiscus sinensis	64.91	0.00e+00	1057.00
IUUC-Pma-094249	Petromyzon marinus	75.00	3.00e-124	437.00
IUUC-Pfo-096049	Poecilia formosa	82.13	0.00e+00	665.00
IUUC-Pab-097595	Pongo abelii	64.85	0.00e+00	1039.00
IUUC-Pca-100844	Procavia capensis	54.43	0.00e+00	703.00
IUUC-Pva-103216	Pteropus vampyrus	60.74	0.00e+00	1005.00
IUUC-Rno-105381	Rattus norvegicus	64.10	0.00e+00	1033.00
IUUC-Sha-107574	Sarcophilus harrisii	64.10	0.00e+00	1011.00
IUUC-Sar-113500	Sorex araneus	55.50	0.00e+00	789.00
IUUC-Ssc-115856	Sus scrofa	61.18	0.00e+00	817.00
IUUC-Tgu-116866	Taeniopygia guttata	64.54	0.00e+00	1039.00
IUUC-Tru-118579	Takifugu rubripes	78.02	0.00e+00	805.00
IUUC-Tsy-119167	Tarsius syrichta	63.41	0.00e+00	705.00
IUUC-Tni-120788	Tetraodon nigroviridis	62.23	0.00e+00	998.00
IUUC-Tbe-127830	Tupaia belangeri	68.60	0.00e+00	785.00
IUUC-Ttr-128631	Tursiops truncatus	64.78	0.00e+00	1037.00
IUUC-Vpa-130713	Vicugna pacos	65.24	0.00e+00	902.00
IUUC-Xtr-131926	Xenopus tropicalis	78.68	0.00e+00	831.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence