iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065867

Ensembl Protein ID

ENSMPUP00000004706.1

UniProt Accession

M3Y055; M3Y055_MUSPF

Genbank Protein ID

ENSMPUP00000004706

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01049412

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000004744.1	ENSMPUT00000004788.1	ENSMPUP00000004706.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	9.60e-13	47.9	448	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            +lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 448  VALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--LCRGRYGLFPANYVE 497
           69***********************..9*********..9************97 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MWKASAGHAV SITQDDVGSD DWETDPDFVN DVSEKEQRWG AKTVKGSGHQ EHINIHKLRE 60
NVFQEHQTLK EKELETGPKA SHGYGGKFGV EQDRMDKSAV GHEYQSKLSK HCSQVDSVRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGAGTCAC TCCCAAATGC TGGAAGTTCC TCGCAGGAGC ACTGGCTTTC CACAGGGACC 60
CCTGAGCAGC CTTTTGTCGC CAGCTGGAAA GAAAGGTTTG TGCCCCGTGA GCGTCTCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	84.97	0.00e+00	860.00
IUUC-Apl-003745	Anas platyrhynchos	72.10	0.00e+00	691.00
IUUC-Aca-004438	Anolis carolinensis	65.89	0.00e+00	704.00
IUUC-Ame-011504	Astyanax mexicanus	50.93	2.00e-120	425.00
IUUC-Bta-013563	Bos taurus	77.51	0.00e+00	782.00
IUUC-Bci-013690	Botrytis cinerea	57.14	2.00e-11	64.70
IUUC-Cel-018639	Caenorhabditis elegans	39.47	5.00e-19	89.40
IUUC-Cfa-020718	Canis familiaris	84.84	0.00e+00	863.00
IUUC-Cpo-022303	Cavia porcellus	79.42	0.00e+00	870.00
IUUC-Csa-023431	Chlorocebus sabaeus	82.15	0.00e+00	836.00
IUUC-Cin-025677	Ciona intestinalis	54.14	7.00e-100	357.00
IUUC-Csv-026140	Ciona savignyi	60.07	9.00e-95	340.00
IUUC-Dre-028012	Danio rerio	69.34	0.00e+00	634.00
IUUC-Dno-029332	Dasypus novemcinctus	85.96	0.00e+00	781.00
IUUC-Dme-031931	Drosophila melanogaster	47.37	2.00e-81	296.00
IUUC-Eca-033801	Equus caballus	83.33	0.00e+00	817.00
IUUC-Fca-035633	Felis catus	78.56	0.00e+00	682.00
IUUC-Fal-036775	Ficedula albicollis	74.86	0.00e+00	691.00
IUUC-Fox-037778	Fusarium oxysporum	61.82	5.00e-14	73.60
IUUC-Gmo-038507	Gadus morhua	58.23	1.00e-20	94.00
IUUC-Gga-040568	Gallus gallus	74.68	0.00e+00	712.00
IUUC-Gac-042253	Gasterosteus aculeatus	57.43	1.00e-113	403.00
IUUC-Hsa-046818	Homo sapiens	82.51	0.00e+00	837.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	76.14	0.00e+00	779.00
IUUC-Lch-050199	Latimeria chalumnae	61.11	5.00e-119	421.00
IUUC-Loc-052855	Lepisosteus oculatus	83.44	1.00e-158	552.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	4.00e-12	67.00
IUUC-Laf-053866	Loxodonta africana	78.73	0.00e+00	851.00
IUUC-Mcc-055515	Macaca mulatta	77.41	0.00e+00	814.00
IUUC-Mga-059791	Meleagris gallopavo	71.48	0.00e+00	709.00
IUUC-Mmr-061147	Microcebus murinus	82.03	0.00e+00	762.00
IUUC-Mdo-062660	Monodelphis domestica	64.63	3.00e-176	612.00
IUUC-Mmu-064023	Mus musculus	81.47	0.00e+00	822.00
IUUC-Mlu-067704	Myotis lucifugus	76.46	0.00e+00	742.00
IUUC-Ont-071873	Oreochromis niloticus	72.83	1.00e-145	509.00
IUUC-Oan-073528	Ornithorhynchus anatinus	68.33	4.00e-138	484.00
IUUC-Oga-088028	Otolemur garnettii	80.69	0.00e+00	812.00
IUUC-Oar-090203	Ovis aries	76.60	0.00e+00	715.00
IUUC-Pan-092594	Papio anubis	75.27	0.00e+00	781.00
IUUC-Psi-093389	Pelodiscus sinensis	73.94	0.00e+00	709.00
IUUC-Pma-094161	Petromyzon marinus	46.67	2.00e-84	306.00
IUUC-Pfo-096269	Poecilia formosa	66.16	2.00e-112	399.00
IUUC-Pab-097913	Pongo abelii	82.42	0.00e+00	813.00
IUUC-Rno-105489	Rattus norvegicus	76.70	0.00e+00	780.00
IUUC-Sha-107308	Sarcophilus harrisii	72.39	0.00e+00	675.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	55.17	1.00e-14	75.10
IUUC-Tgu-117049	Taeniopygia guttata	80.35	0.00e+00	725.00
IUUC-Tru-118718	Takifugu rubripes	70.67	4.00e-146	511.00
IUUC-Tni-120535	Tetraodon nigroviridis	58.96	2.00e-172	598.00
IUUC-Tre-122167	Trichoderma reesei	59.18	2.00e-11	64.70
IUUC-Tvi-122614	Trichoderma virens	59.18	1.00e-11	65.10
IUUC-Vda-129766	Verticillium dahliae	58.18	2.00e-13	71.20
IUUC-Xtr-131797	Xenopus tropicalis	60.70	6.00e-170	590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence