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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064101
Ensembl Protein ID ENSMUSP00000113309.1
UniProt Accession E9Q743; Q8BMR0; Q9D3X6; CF251_MOUSE
Genbank Protein ID BAC26877.1; BAB30526.1
Protein Name Cilia- and flagella-associated protein 251; WD repeat-containing protein 66
Genbank Nucleotide ID AC113504; AK016965
Gene Name Wdr66
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000029442.18 ENSMUST00000121964.7 ENSMUSP00000113309.1
ENSMUSG00000029442.18 ENSMUST00000150155.7 ENSMUSP00000118944.1
ENSMUSG00000029442.18 ENSMUST00000069311.4 ENSMUSP00000069782.4
ENSMUSG00000029442.18 ENSMUST00000163092.7 ENSMUSP00000126995.1
ENSMUSG00000029442.18 ENSMUST00000170536.1 ENSMUSP00000129769.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRAID2
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.10e-06 28.1 757 785
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDl 30
           d v++++  +  +l+++Gs  g ikvWD+
   Q: 757  DAVYAVSChPYqPLIAVGSVCGMIKVWDF 785
           5677777775669***************6 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May regulate cilium motility through its role in the assembly of the axonemal radialsQ7Z4T9spokes.
 May regulate cilium motility through its role in the assembly of the axonemal radialsQ7Z4T9spokes.
Protein Sequence
(Fasta)
MSDTEENPLE ESRESGEMEE EKEEKKEEEE EEEEGEKEKE EEEEEEKGKE EEKEEEKEEG 60
KEEEKKEEEE EKGKKEEEEE EEEEGKGKEE EKEEEKEEEE KEEEKEKEEE EEEEGKGKEE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064101|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGAGCTTGGT TGGCAACCGT CACTAGGGAG TATGGACAGG AGCCCCTGGA GGTCTCTTGG 60
GATTTCCCGA GGCTGGACGA CCCAAGGCTT TTGAGAAAAG AAGTGGGAGC GTCCCTGTAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064101|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR011992--EF-hand-dom_pair
IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
Pfam

PF00400--WD40
SMART

SM00320--WD40
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002305 Ailuropoda melanoleuca 78.69 0.00e+00 1611.00
IUUC-Apl-003833 Anas platyrhynchos 54.69 0.00e+00 977.00
IUUC-Ame-011318 Astyanax mexicanus 48.98 0.00e+00 879.00
IUUC-Bta-013319 Bos taurus 80.04 0.00e+00 1565.00
IUUC-Cja-019874 Callithrix jacchus 77.16 0.00e+00 1608.00
IUUC-Cfa-021224 Canis familiaris 78.12 0.00e+00 1615.00
IUUC-Cpo-022038 Cavia porcellus 68.08 0.00e+00 1321.00
IUUC-Cre-022950 Chlamydomonas reinhardtii 28.29 1.00e-60 228.00
IUUC-Csa-024266 Chlorocebus sabaeus 78.60 0.00e+00 1533.00
IUUC-Cin-025361 Ciona intestinalis 43.86 0.00e+00 821.00
IUUC-Csv-026051 Ciona savignyi 42.87 0.00e+00 785.00
IUUC-Dre-028130 Danio rerio 45.87 0.00e+00 880.00
IUUC-Dno-029069 Dasypus novemcinctus 76.72 0.00e+00 1099.00
IUUC-Ete-032698 Echinops telfairi 66.53 0.00e+00 702.00
IUUC-Eca-033728 Equus caballus 80.37 0.00e+00 1589.00
IUUC-Eeu-034707 Erinaceus europaeus 81.23 3.00e-137 483.00
IUUC-Fca-035974 Felis catus 78.59 0.00e+00 1568.00
IUUC-Fal-037073 Ficedula albicollis 51.23 0.00e+00 963.00
IUUC-Gmo-039607 Gadus morhua 47.89 3.00e-147 515.00
IUUC-Gga-040440 Gallus gallus 53.23 0.00e+00 981.00
IUUC-Gac-042234 Gasterosteus aculeatus 44.19 0.00e+00 773.00
IUUC-Ggo-044473 Gorilla gorilla 84.56 0.00e+00 1040.00
IUUC-Hsa-046770 Homo sapiens 78.94 0.00e+00 1630.00
IUUC-Itr-049034 Ictidomys tridecemlineatus 76.39 0.00e+00 1501.00
IUUC-Lch-049489 Latimeria chalumnae 47.16 0.00e+00 880.00
IUUC-Loc-052793 Lepisosteus oculatus 53.13 0.00e+00 1009.00
IUUC-Laf-054246 Loxodonta africana 78.88 0.00e+00 744.00
IUUC-Mcc-054827 Macaca mulatta 77.37 0.00e+00 1563.00
IUUC-Meu-056344 Macropus eugenii 61.48 0.00e+00 882.00
IUUC-Mga-059830 Meleagris gallopavo 52.95 0.00e+00 965.00
IUUC-Mmr-061157 Microcebus murinus 76.93 0.00e+00 1570.00
IUUC-Mdo-062870 Monodelphis domestica 66.27 0.00e+00 1318.00
IUUC-Mpu-066432 Mustela putorius furo 80.10 0.00e+00 1588.00
IUUC-Mlu-068011 Myotis lucifugus 73.72 0.00e+00 1429.00
IUUC-Nle-069572 Nomascus leucogenys 71.46 0.00e+00 1467.00
IUUC-Opr-070235 Ochotona princeps 78.71 0.00e+00 1456.00
IUUC-Oan-073735 Ornithorhynchus anatinus 65.35 0.00e+00 1254.00
IUUC-Ocu-074669 Oryctolagus cuniculus 76.83 0.00e+00 1481.00
IUUC-Oga-089007 Otolemur garnettii 79.52 0.00e+00 1616.00
IUUC-Ptr-091286 Pan troglodytes 78.74 0.00e+00 1630.00
IUUC-Pan-091905 Papio anubis 78.88 0.00e+00 1609.00
IUUC-Psi-093555 Pelodiscus sinensis 56.26 0.00e+00 1047.00
IUUC-Pma-094736 Petromyzon marinus 36.62 0.00e+00 647.00
IUUC-Pfo-097081 Poecilia formosa 41.82 0.00e+00 751.00
IUUC-Pab-097893 Pongo abelii 77.51 0.00e+00 1591.00
IUUC-Rno-105786 Rattus norvegicus 85.53 0.00e+00 1760.00
IUUC-Sha-107399 Sarcophilus harrisii 65.00 0.00e+00 1287.00
IUUC-Tgu-116796 Taeniopygia guttata 53.49 0.00e+00 1004.00
IUUC-Tru-118592 Takifugu rubripes 43.48 0.00e+00 729.00
IUUC-Tni-120456 Tetraodon nigroviridis 40.47 0.00e+00 676.00
IUUC-Tbe-127411 Tupaia belangeri 74.19 1.00e-91 331.00
IUUC-Xtr-131990 Xenopus tropicalis 51.90 0.00e+00 986.00
Created Date 25-Jun-2017

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