iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089288

Ensembl Protein ID

ENSOARP00000005595.1

UniProt Accession

W5P592; W5P592_SHEEP

Genbank Protein ID

ENSOARP00000005595

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01025852

Gene Name

EFCAB8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005212.1	ENSOART00000005682.1	ENSOARP00000005595.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-20	72.9	407	432
UBD/Beta-Prp	2.20e-44	152.0	407	627

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf.sd.tllvsGsdDgtikvWD 29
           + c+++ +d + lv+G++D  i++W+
   Q: 407  ILCFDYcPDkNVLVTGGYDPLIRLWN 432
           889999*999***************9 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl.lrslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkgheds... 96
           i c ++ pdk++l+tg++d  i++w+ +   + ++ ++gh+  vt v  +++g+ il ++s+D++i+vwd+++++c++++ g+ +    
   Q: 407  ILCFDYCPDKNVLVTGGYDPLIRLWNPFFSRKpVWLMKGHQTSVTHVVVNSKGSsILFSVSKDKNIRVWDMQDYQCLQSFCGKHFAlgh 495
           44577889999999999999999998665444377779999999999998888889999999999999999999999999987775222 PP
   S: 97   ..vlslsfspsg.dklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtl..tgg 178
             ++s+ f++++ + + s+ +  +++ + let+   ++  ++ ++++  c+v+ ++  + +vsG+l ++v +W   tg+ l ++  tg+
   Q: 496  cpITSIYFHKEDnSLICSTYSIGILKGY-LETQGPGRAeEKTTTHSTPLCAVLYSKVfKQVVSGCLSGMVSVWEAVTGRKLMEFsvTGD 583
           2266788888553777777788888888.44444333347888888888988888888**************************99998 PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
           ++   + +s+d++  +l++g +dgt+k+w+++ gec+ t+   +
   Q: 584  QQVELTAMSLDESEGCLLTGLRDGTIKMWNYSVGECLLTFPSAD 627
           999999999****************************9997665 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSQPRRKLNT NKPPLNTASS LNWGEQIGSG SRPVSSEDLR DKPLPRKVSF AGGPGKNKEV 60
LSSPTPSISV SQTSDFQYES QLFTEANLAE MEKTFQSEVN STGALDMKTF IKAVRKILSN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTCTG ATGTTCCATT TTGTGTTCTG CGTGTGGAAT TCTGTCTCAT TTTCCTGGTT 60
CTAAGTGTGG CCAACTGGCC CTGCAGTCTG TGGAGGCCCT CGGAGCTCCA TAGCGACCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005509--F:calcium ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-020006	Callithrix jacchus	70.65	0.00e+00	1120.00
IUUC-Cfa-020765	Canis familiaris	67.56	0.00e+00	1681.00
IUUC-Cre-022835	Chlamydomonas reinhardtii	21.55	1.00e-13	73.20
IUUC-Cin-025265	Ciona intestinalis	27.47	4.00e-72	266.00
IUUC-Dno-029238	Dasypus novemcinctus	59.15	0.00e+00	1441.00
IUUC-Dme-031984	Drosophila melanogaster	24.42	8.00e-48	186.00
IUUC-Gac-041482	Gasterosteus aculeatus	32.34	2.00e-38	153.00
IUUC-Ggo-044932	Gorilla gorilla	67.45	0.00e+00	1657.00
IUUC-Hsa-046963	Homo sapiens	67.37	0.00e+00	1660.00
IUUC-Lch-050281	Latimeria chalumnae	40.75	5.00e-158	551.00
IUUC-Loc-052029	Lepisosteus oculatus	41.35	6.00e-156	544.00
IUUC-Laf-054508	Loxodonta africana	76.02	0.00e+00	711.00
IUUC-Mcc-054635	Macaca mulatta	67.62	0.00e+00	1665.00
IUUC-Mmr-061370	Microcebus murinus	62.74	0.00e+00	1382.00
IUUC-Mdo-061862	Monodelphis domestica	47.55	0.00e+00	1049.00
IUUC-Mmu-063271	Mus musculus	71.39	6.00e-155	540.00
IUUC-Mpu-066224	Mustela putorius furo	66.03	0.00e+00	1639.00
IUUC-Ocu-074664	Oryctolagus cuniculus	68.27	0.00e+00	1332.00
IUUC-Psi-093985	Pelodiscus sinensis	41.53	1.00e-127	449.00
IUUC-Pfo-097353	Poecilia formosa	25.90	2.00e-51	197.00
IUUC-Ssc-115233	Sus scrofa	84.36	3.00e-89	320.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence