iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089227

Ensembl Protein ID

ENSOARP00000017538.1

UniProt Accession

W5Q498; W5Q498_SHEEP

Genbank Protein ID

ENSOARP00000017538

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01091328

Gene Name

KEAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000016335.1	ENSOART00000017786.1	ENSOARP00000017538.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.60e-10	39.9	77	139
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.20e-10	39.6	172	202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv....g.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+v    +   +f ahk+vLa+sS+vF+a++          + v i+++ p+v++ l++F Yt ++++ 
   Q: 77   CDVTLQVkyqdApAAQFMAHKVVLASSSPVFKAMM----------EVVSIEGIHPKVMERLIEFAYTASISMG 139
           8******77552699*******************9..........5799999***************998875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c++L+++a+++i  hF
   Q: 172  PSNAIGIANFAEQIGCTELHQRAREYIYMHF 202
           89****************************9 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MQPEPRPSGA GAHTQFLPLR SQRPEGAGDT VMYASTECKA EVTPSQHGNR TFSYTLEDHT 60
KQAFGIMNEL RLSQQLCDVT LQVKYQDAPA AQFMAHKVVL ASSSPVFKAM MEVVSIEGIH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCCGG AACCCAGGCC TAGCGGGGCC GGGGCCCATA CCCAATTCCT ACCCCTGAGA 60
TCACAGCGCC CCGAGGGGGC AGGGGACACG GTGATGTACG CCTCCACCGA GTGCAAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005884--C:actin filament
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0005654--C:nucleoplasm
GO:0071353--P:cellular response to interleukin-4
GO:0001701--P:in utero embryonic development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0045604--P:regulation of epidermal cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	96.79	0.00e+00	1262.00
IUUC-Aca-005389	Anolis carolinensis	84.82	0.00e+00	1061.00
IUUC-Ame-010749	Astyanax mexicanus	77.21	0.00e+00	946.00
IUUC-Bta-013505	Bos taurus	98.40	0.00e+00	1284.00
IUUC-Cja-018823	Callithrix jacchus	95.67	0.00e+00	1246.00
IUUC-Cfa-021202	Canis familiaris	97.12	0.00e+00	1265.00
IUUC-Cpo-021830	Cavia porcellus	96.60	0.00e+00	844.00
IUUC-Csa-023728	Chlorocebus sabaeus	95.83	0.00e+00	1246.00
IUUC-Cin-025195	Ciona intestinalis	54.48	0.00e+00	664.00
IUUC-Csv-026155	Ciona savignyi	53.06	1.00e-176	612.00
IUUC-Dre-027388	Danio rerio	75.89	0.00e+00	926.00
IUUC-Dno-029066	Dasypus novemcinctus	84.00	0.00e+00	1065.00
IUUC-Dor-030674	Dipodomys ordii	94.89	0.00e+00	832.00
IUUC-Dme-032165	Drosophila melanogaster	48.48	2.00e-154	539.00
IUUC-Ete-032255	Echinops telfairi	93.96	8.00e-99	353.00
IUUC-Eca-034381	Equus caballus	92.61	0.00e+00	1187.00
IUUC-Eeu-034791	Erinaceus europaeus	89.81	0.00e+00	790.00
IUUC-Fca-036067	Felis catus	96.47	0.00e+00	1258.00
IUUC-Gmo-039691	Gadus morhua	75.68	0.00e+00	924.00
IUUC-Gga-040266	Gallus gallus	78.86	0.00e+00	984.00
IUUC-Gac-041866	Gasterosteus aculeatus	75.59	0.00e+00	926.00
IUUC-Ggo-044719	Gorilla gorilla	96.31	0.00e+00	1252.00
IUUC-Hsa-046255	Homo sapiens	96.31	0.00e+00	1252.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	95.35	0.00e+00	1239.00
IUUC-Lch-049646	Latimeria chalumnae	82.03	0.00e+00	1022.00
IUUC-Loc-052296	Lepisosteus oculatus	56.45	0.00e+00	631.00
IUUC-Laf-054579	Loxodonta africana	95.35	0.00e+00	1246.00
IUUC-Mcc-055315	Macaca mulatta	95.83	0.00e+00	1246.00
IUUC-Meu-056288	Macropus eugenii	88.32	0.00e+00	1098.00
IUUC-Mmr-061639	Microcebus murinus	95.67	0.00e+00	1252.00
IUUC-Mdo-062072	Monodelphis domestica	92.47	0.00e+00	1196.00
IUUC-Mmu-063622	Mus musculus	93.27	0.00e+00	1219.00
IUUC-Mpu-066737	Mustela putorius furo	94.23	0.00e+00	1220.00
IUUC-Mlu-068173	Myotis lucifugus	96.47	0.00e+00	1257.00
IUUC-Nle-069336	Nomascus leucogenys	55.80	2.00e-172	598.00
IUUC-Opr-070432	Ochotona princeps	95.49	0.00e+00	1200.00
IUUC-Ont-072160	Oreochromis niloticus	76.13	0.00e+00	925.00
IUUC-Oan-072691	Ornithorhynchus anatinus	79.66	0.00e+00	961.00
IUUC-Ocu-073798	Oryctolagus cuniculus	94.71	0.00e+00	1242.00
IUUC-Ola-086367	Oryzias latipes	73.36	0.00e+00	889.00
IUUC-Oga-088231	Otolemur garnettii	96.31	0.00e+00	1255.00
IUUC-Ptr-091460	Pan troglodytes	96.31	0.00e+00	1252.00
IUUC-Pan-092713	Papio anubis	95.83	0.00e+00	1246.00
IUUC-Pfo-096468	Poecilia formosa	76.74	0.00e+00	929.00
IUUC-Pab-098357	Pongo abelii	96.47	0.00e+00	1255.00
IUUC-Pca-100837	Procavia capensis	94.07	0.00e+00	1224.00
IUUC-Pva-103249	Pteropus vampyrus	94.07	0.00e+00	1195.00
IUUC-Rno-106086	Rattus norvegicus	92.79	0.00e+00	1207.00
IUUC-Sha-107245	Sarcophilus harrisii	92.15	0.00e+00	1192.00
IUUC-Sar-112985	Sorex araneus	94.39	0.00e+00	1233.00
IUUC-Ssc-115756	Sus scrofa	97.76	0.00e+00	1275.00
IUUC-Tgu-116838	Taeniopygia guttata	51.83	2.00e-111	395.00
IUUC-Tru-117644	Takifugu rubripes	75.79	0.00e+00	951.00
IUUC-Tni-120245	Tetraodon nigroviridis	76.66	0.00e+00	936.00
IUUC-Tbe-127472	Tupaia belangeri	98.37	7.00e-149	520.00
IUUC-Ttr-128953	Tursiops truncatus	96.09	0.00e+00	702.00
IUUC-Vpa-130683	Vicugna pacos	93.85	0.00e+00	1095.00
IUUC-Xtr-132827	Xenopus tropicalis	74.57	0.00e+00	926.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence