iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-073798

UUCD1 version

UUC-OrC-00055

Ensembl Protein ID

ENSOCUP00000001235.3

UniProt Accession

G1SFF4; G1SFF4_RABIT

Protein Name

Uncharacterized protein

Gene Name

KEAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000001435.3	ENSOCUT00000001434.3	ENSOCUP00000001235.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.10e-17	61.2	77	148
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.40e-09	34.8	181	211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv.....ggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+v        +f ahk+vLa+sS+vF+a+f+++l+e+   + v i+++ p+v++ l++F Yt ++++ 
   Q: 77   CDVTLQVkyedtPAAQFMAHKVVLASSSPVFKAMFTNGLREQG-MEVVSIEGIHPQVMERLIEFAYTASISMG 148
           89*****66653399**************************98.***********************998875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c +L+++a+++i  hF
   Q: 181  PSNAIGIANFAEQIGCAELHQRAREYIYMHF 211
           89****************************9 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MQPEAEPSGA EACSRFLPQQ SQRPEGAGDA MMFASTECKA EVTPSQHGNR TFSYTLEDHT 60
KQAFGIMNEL RLSQQLCDVT LQVKYEDTPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCTGAGT GTCCGTGGCG GCGTGATCCC TTGTCACTTG GAACCTCATG CAGCCGGAAG 60
CCGAGCCTAG CGGGGCGGAG GCCTGCAGCC GATTCCTGCC CCAGCAGTCA CAGCGCCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005884--C:actin filament
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0005654--C:nucleoplasm
GO:0071353--P:cellular response to interleukin-4
GO:0001701--P:in utero embryonic development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0045604--P:regulation of epidermal cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

ocu:100346935

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	96.31	0.00e+00	1271.00
IUUC-Aca-005389	Anolis carolinensis	86.51	0.00e+00	1089.00
IUUC-Ame-010749	Astyanax mexicanus	78.49	0.00e+00	965.00
IUUC-Bta-013505	Bos taurus	96.15	0.00e+00	1269.00
IUUC-Cja-018823	Callithrix jacchus	95.67	0.00e+00	1261.00
IUUC-Cfa-021202	Canis familiaris	96.63	0.00e+00	1273.00
IUUC-Cpo-021830	Cavia porcellus	95.39	0.00e+00	840.00
IUUC-Csa-023728	Chlorocebus sabaeus	95.67	0.00e+00	1259.00
IUUC-Cin-025195	Ciona intestinalis	55.69	0.00e+00	681.00
IUUC-Csv-026155	Ciona savignyi	54.29	0.00e+00	630.00
IUUC-Dre-027388	Danio rerio	77.29	0.00e+00	947.00
IUUC-Dno-029066	Dasypus novemcinctus	84.80	0.00e+00	1083.00
IUUC-Dor-030674	Dipodomys ordii	94.40	0.00e+00	833.00
IUUC-Dme-032165	Drosophila melanogaster	49.91	7.00e-162	564.00
IUUC-Ete-032255	Echinops telfairi	92.31	4.00e-98	351.00
IUUC-Eca-034381	Equus caballus	93.10	0.00e+00	1207.00
IUUC-Eeu-034791	Erinaceus europaeus	96.05	0.00e+00	814.00
IUUC-Fca-036067	Felis catus	96.15	0.00e+00	1267.00
IUUC-Gmo-039691	Gadus morhua	76.70	0.00e+00	944.00
IUUC-Gga-040266	Gallus gallus	79.70	0.00e+00	1001.00
IUUC-Gac-041866	Gasterosteus aculeatus	76.95	0.00e+00	951.00
IUUC-Ggo-044719	Gorilla gorilla	96.15	0.00e+00	1267.00
IUUC-Hsa-046255	Homo sapiens	96.15	0.00e+00	1267.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	96.47	0.00e+00	1264.00
IUUC-Lch-049646	Latimeria chalumnae	83.30	0.00e+00	1045.00
IUUC-Loc-052296	Lepisosteus oculatus	58.01	0.00e+00	652.00
IUUC-Laf-054579	Loxodonta africana	95.67	0.00e+00	1259.00
IUUC-Mcc-055315	Macaca mulatta	95.67	0.00e+00	1259.00
IUUC-Meu-056288	Macropus eugenii	88.30	0.00e+00	1133.00
IUUC-Mmr-061639	Microcebus murinus	95.51	0.00e+00	1261.00
IUUC-Mdo-062072	Monodelphis domestica	93.59	0.00e+00	1225.00
IUUC-Mmu-063622	Mus musculus	93.27	0.00e+00	1233.00
IUUC-Mpu-066737	Mustela putorius furo	93.59	0.00e+00	1226.00
IUUC-Mlu-068173	Myotis lucifugus	95.51	0.00e+00	1260.00
IUUC-Nle-069336	Nomascus leucogenys	60.48	0.00e+00	687.00
IUUC-Opr-070432	Ochotona princeps	97.50	0.00e+00	1231.00
IUUC-Ont-072160	Oreochromis niloticus	77.14	0.00e+00	946.00
IUUC-Oan-072691	Ornithorhynchus anatinus	80.57	0.00e+00	982.00
IUUC-Ola-086367	Oryzias latipes	74.20	0.00e+00	912.00
IUUC-Oga-088231	Otolemur garnettii	95.51	0.00e+00	1257.00
IUUC-Oar-089227	Ovis aries	94.71	0.00e+00	1242.00
IUUC-Ptr-091460	Pan troglodytes	96.15	0.00e+00	1267.00
IUUC-Pan-092713	Papio anubis	95.67	0.00e+00	1259.00
IUUC-Pfo-096468	Poecilia formosa	77.76	0.00e+00	950.00
IUUC-Pab-098357	Pongo abelii	96.15	0.00e+00	1268.00
IUUC-Pca-100837	Procavia capensis	94.55	0.00e+00	1238.00
IUUC-Pva-103249	Pteropus vampyrus	93.43	0.00e+00	1201.00
IUUC-Rno-106086	Rattus norvegicus	92.79	0.00e+00	1221.00
IUUC-Sha-107245	Sarcophilus harrisii	93.11	0.00e+00	1220.00
IUUC-Sar-112985	Sorex araneus	94.39	0.00e+00	1248.00
IUUC-Ssc-115756	Sus scrofa	96.63	0.00e+00	1273.00
IUUC-Tgu-116838	Taeniopygia guttata	53.66	5.00e-118	417.00
IUUC-Tru-117644	Takifugu rubripes	76.45	0.00e+00	971.00
IUUC-Tni-120245	Tetraodon nigroviridis	77.34	0.00e+00	956.00
IUUC-Tbe-127472	Tupaia belangeri	96.33	7.00e-148	517.00
IUUC-Ttr-128953	Tursiops truncatus	94.97	0.00e+00	702.00
IUUC-Vpa-130683	Vicugna pacos	93.67	0.00e+00	1102.00
IUUC-Xtr-132827	Xenopus tropicalis	76.33	0.00e+00	953.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence